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    Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture von Forgetta, Vincenzo, Estrada, Karol, Leo, Paul J., Dahia, Chitra L., Liu, Ching‐Ti, Uggla, Charlotta, Evans, Daniel S., Walter, Klaudia, Pettersson‐Kymmer, Ulrika, McCarthy, Shane, Kwan, Tony, Jhamai, Mila, Trajanoska, Katerina, Huang, Jie, Danecek, Petr, Wilmot, Beth, Li, Rui, Moayyeri, Alireza, Claussnitzer, Melina, Cheng, Chia‐Ho, Cheung, Warren, Ge, Bing, Chen, Shu‐Huang, Choi, Kwangbom, Oei, Ling, Fraser, James, Hibbs, Matthew A., Gregson, Celia L., Paquette, Denis, Wibom, Carl, Tranah, Gregory J., Marshall, Mhairi, Gardiner, Brooke B., Cremin, Katie, Auer, Paul, Hsu, Li, Thorleifsson, Gudmar, Enneman, Anke W., de Groot, Lisette C. P. G. M., Melin, Beatrice, Christiansen, Claus, Sayers, Adrian, Zhou, Yanhua, Calderari, Sophie, van Rooij, Jeroen, Carlson, Chris, Peters, Ulrike, Uitterlinden, Andre G., Williams, Stephen R., Farber, Charles, Grinberg, Daniel, Chasman, Daniel I., Giulianini, Franco, Ridker, Paul M., Eisman, John A., Nguyen, Tuan V., Center, Jacqueline R., Garcia‐Giralt, Natalia, Mellström, Dan, Vandenput, Liesbeth, Amin, Najaf, van Duijn, Cornelia M., Karlsson, Magnus K., Svensson, Olle, Rousseau, François, Bussière, Johanne, Koromani, Fjorda, Langdahl, Bente L., Jensen, Jens‐Erik B., Kaptoge, Stephen, Khaw, Kay‐Tee, Reeve, Jonathan, Xuereb‐Anastasi, Angela, Åkesson, Kristina, Olmos, Jose M., Zarrabeitia, Maria T., Riancho, Jose A., Alonso, Nerea, Jiang, Xi, Goltzman, David, Grundberg, Elin, Gauguier, Dominique, Orwoll, Eric S., Karasik, David, Davey‐Smith, George, Smith, Albert V., Harris, Tamara B., Carola Zillikens, M., Thorsteinsdottir, Unnur, Soranzo, Nicole, Durbin, Richard, Brown, Matthew A., Spector, Tim, Adrienne Cupples, L., Greenwood, Celia M. T., Jackson, Rebecca D., Rowe, David W., Loomis, Cynthia A., Ackert‐Bicknell, Cheryl L., Kiel, Douglas P.

    Veröffentlicht in Nature (London)

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    Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture von Estrada, Karol, Styrkarsdottir, Unnur, Evangelou, Evangelos, Hsu, Yi-Hsiang, Ntzani, Evangelia E, Albagha, Omar M E, Koller, Daniel L, Minster, Ryan L, Moayyeri, Alireza, Vandenput, Liesbeth, Willner, Dana, Xiao, Su-Mei, Zheng, Hou-Feng, Alonso, Nerea, Kammerer, Candace M, Kaptoge, Stephen K, Leo, Paul J, Wilson, James F, Alen, Markku, Aspelund, Thor, Center, Jacqueline R, Dailiana, Zoe, Duggan, David J, Garcia, Melissa, Husted, Lise Bjerre, Jameson, Karen A, Kim, Ghi Su, Kooperberg, Charles, Kruk, Marcin, Laaksonen, Marika, Leung, Ping C, Lewis, Joshua R, Nogues, Xavier, Prezelj, Janez, Scollen, Serena, Svensson, Olle, Trompet, Stella, Woo, Jean, Zhu, Kun, Cheng, Sulin, Dedoussis, George, Frost, Morten, Goltzman, David, Kähönen, Mika, Karlsson, Magnus, Langdahl, Bente Lomholt, Lips, Paul, Lorenc, Roman S, Mellström, Dan, Olmos, José M, Pettersson-Kymmer, Ulrika, Riancho, José A, Ridker, Paul M, Rousseau, François, lagboom, P Eline S, Urreizti, Roser, Zarrabeitia, María T, Castano-Betancourt, Martha, Kwan, Tony, Li, Rui, Luben, Robert, Medina-Gómez, Carolina, Th Palsson, Stefan, Rotter, Jerome I, Sigurdsson, Gunnar, van Meurs, Joyce B J, Williams, Frances M K, Zhou, Yanhua, Pastinen, Tomi, Cauley, Jane A, Chasman, Daniel I, Clark, Graeme R, Cummings, Steven R, Eastell, Richard, Eisman, John A, Hofman, Albert, Jukema, J Wouter, Khaw, Kay-Tee, Lehtimäki, Terho, Liu, Yongmei, Oostra, Ben A, Pols, Huibert A P, Reid, Ian R, Robbins, John, Sambrook, Philip N, Sham, Pak Chung, Shuldiner, Alan R, van Duijn, Cornelia M, Wareham, Nick J, Econs, Michael J, Harris, Tamara B, Kung, Annie Wai Chee, Streeten, Elizabeth A, Thorsteinsdottir, Unnur, Karasik, David, Richards, J Brent, Brown, Matthew A, Ralston, Stuart H, Ioannidis, John P A, Kiel, Douglas P

    Veröffentlicht in Nature genetics

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    Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies von Sarwar, Nadeem, Butterworth, Adam S, Freitag, Daniel F, Gregson, John, Willeit, Peter, Gorman, Donal N, Gao, Pei, Saleheen, Danish, Rendon, Augusto, Nelson, Christopher P, Braund, Peter S, Hall, Alistair S, Chasman, Daniel I, Tybjærg-Hansen, Anne, Chambers, John C, Benjamin, Emelia J, Franks, Paul W, Clarke, Robert, Wilde, Arthur A M, Trip, Mieke D, Steri, Maristella, Witteman, Jacqueline C M, Qi, Lu, van der Schoot, C Ellen, de Faire, Ulf, Erdmann, Jeanette, Stringham, Heather M, Koenig, Wolfgang, Rader, Daniel J, Melzer, David, Reich, David, Psaty, Bruce M, Kleber, Marcus E, Panagiotakos, Demosthenes B, Willeit, Johann, Wennberg, Patrik, Woodward, Mark, Adamovic, Svetlana, Rimm, Eric B, Meade, Tom W, Gillum, Richard F, Shaffer, Jonathan A, Hofman, Albert, Onat, Altan, Sundström, Johan, Wassertheil-Smoller, Sylvia, Mellström, Dan, Gallacher, John, Cushman, Mary, Tracy, Russell P, Kauhanen, Jussi, Karlsson, Magnus, Salonen, Jukka T, Wilhelmsen, Lars, Amouyel, Philippe, Cantin, Bernard, Best, Lyle G, Ben-Shlomo, Yoav, Manson, JoAnn E, Davey-Smith, George, de Bakker, Paul I W, O'Donnell, Christopher J, Wilson, James F, Wilson, Anthony G, Assimes, Themistocles L, Jansson, John-Olov, Ohlsson, Claes, Tivesten, Åsa, Ljunggren, Östen, Reilly, Muredach P, Hamsten, Anders, Ingelsson, Erik, Cambien, Francois, Hung, Joseph, Thomas, G Neil, Boehnke, Michael, Schunkert, Heribert, Asselbergs, Folkert W, Kastelein, John J P, Gudnason, Vilmundur, Salomaa, Veikko, Harris, Tamara B, Kooner, Jaspal S, Allin, Kristine H, Nordestgaard, Børge G, Hopewell, Jemma C, Goodall, Alison H, Ridker, Paul M, Hólm, Hilma, Watkins, Hugh, Ouwehand, Willem H, Samani, Nilesh J, Kaptoge, Stephen, Di Angelantonio, Emanuele, Harari, Olivier, Danesh, John

    Veröffentlicht in The Lancet (British edition)

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    Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile von Kilpeläinen, Tuomas O, Zillikens, M Carola, Stančákova, Alena, Finucane, Francis M, Ried, Janina S, Langenberg, Claudia, Zhang, Weihua, Beckmann, Jacques S, Luan, Jian'an, Vandenput, Liesbeth, Styrkarsdottir, Unnur, Zhou, Yanhua, Smith, Albert Vernon, Zhao, Jing-Hua, Amin, Najaf, Vedantam, Sailaja, Shin, So-Youn, Haritunians, Talin, Fu, Mao, Feitosa, Mary F, Kumari, Meena, Halldorsson, Bjarni V, Tikkanen, Emmi, Mangino, Massimo, Hayward, Caroline, Song, Ci, Aulchenko, Yurii S, Oostra, Ben A, Campbell, Harry, Cupples, L Adrienne, Davis, Kathryn E, Döring, Angela, Eiriksdottir, Gudny, Estrada, Karol, Garcia, Melissa, Gieger, Christian, Glazer, Nicole L, Guiducci, Candace, Hofman, Albert, Humphries, Steve E, Isomaa, Bo, Jula, Antti, Karasik, David, Karlsson, Magnus K, Khaw, Kay-Tee, Kim, Lauren J, Kühnel, Brigitte, Kuusisto, Johanna, Liu, Yongmei, Ljunggren, Östen, Lorentzon, Mattias, McKnight, Barbara, Mellström, Dan, Mitchell, Braxton D, Moreno, José Maria, Männistö, Satu, O'Connell, Jeffery R, Pascoe, Laura, Peltonen, Leena, Perola, Markus, Psaty, Bruce M, Savage, David B, Semple, Robert K, Skaric-Juric, Tatjana, Song, Kijoung S, Spector, Timothy D, Syvänen, Ann-Christine, Talmud, Philippa J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Uitterlinden, André G, van Duijn, Cornelia M, Vidal-Puig, Antonio, Wild, Sarah H, Wright, Alan F, Clegg, Deborah J, Schadt, Eric, Rudan, Igor, Ripatti, Samuli, Borecki, Ingrid B, Shuldiner, Alan R, Ingelsson, Erik, Jansson, John-Olov, Kaplan, Robert C, Kiel, Douglas P, Rivadeneira, Fernando, Walker, Mark, Barroso, Inês, Vollenweider, Peter, Waeber, Gérard, Chambers, John C, Kooner, Jaspal S, Soranzo, Nicole, Hirschhorn, Joel N, O'Rahilly, Stephen, Wareham, Nicholas J, Speliotes, Elizabeth K, Fox, Caroline S, Laakso, Markku, Loos, Ruth J F

    Veröffentlicht in Nature genetics

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    A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation von Coviello, Andrea D, Haring, Robin, Wellons, Melissa, Vaidya, Dhananjay, Lehtimäki, Terho, Keildson, Sarah, Lunetta, Kathryn L, He, Chunyan, Fornage, Myriam, Lagou, Vasiliki, Mangino, Massimo, Onland-Moret, N Charlotte, Chen, Brian, Eriksson, Joel, Garcia, Melissa, Liu, Yong Mei, Koster, Annemarie, Lohman, Kurt, Lyytikäinen, Leo-Pekka, Petersen, Ann-Kristin, Prescott, Jennifer, Stolk, Lisette, Vandenput, Liesbeth, Wood, Andrew R, Zhuang, Wei Vivian, Ruokonen, Aimo, Hartikainen, Anna-Liisa, Pouta, Anneli, Bandinelli, Stefania, Biffar, Reiner, Brabant, Georg, Cox, David G, Chen, Yuhui, Cummings, Steven, Ferrucci, Luigi, Gunter, Marc J, Hankinson, Susan E, Martikainen, Hannu, Hofman, Albert, Homuth, Georg, Illig, Thomas, Jansson, John-Olov, Johnson, Andrew D, Karasik, David, Karlsson, Magnus, Kettunen, Johannes, Kiel, Douglas P, Kraft, Peter, Liu, Jingmin, Ljunggren, Östen, Lorentzon, Mattias, Maggio, Marcello, Markus, Marcello R P, Mellström, Dan, Miljkovic, Iva, Mirel, Daniel, Nelson, Sarah, Morin Papunen, Laure, Peeters, Petra H M, Prokopenko, Inga, Raffel, Leslie, Reincke, Martin, Reiner, Alex P, Rexrode, Kathryn, Rivadeneira, Fernando, Schwartz, Stephen M, Siscovick, David, Soranzo, Nicole, Stöckl, Doris, Tworoger, Shelley, Uitterlinden, André G, van Gils, Carla H, Vasan, Ramachandran S, Wichmann, H-Erich, Zhai, Guangju, Bhasin, Shalender, Bidlingmaier, Martin, Chanock, Stephen J, De Vivo, Immaculata, Harris, Tamara B, Hunter, David J, Kähönen, Mika, Liu, Simin, Ouyang, Pamela, Spector, Tim D, van der Schouw, Yvonne T, Viikari, Jorma, Wallaschofski, Henri, McCarthy, Mark I, Frayling, Timothy M, Murray, Anna, Franks, Steve, Järvelin, Marjo-Riitta, de Jong, Frank H, Raitakari, Olli, Teumer, Alexander, Ohlsson, Claes, Murabito, Joanne M, Perry, John R B

    Veröffentlicht in PLoS genetics

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    Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium von Moayyeri, Alireza, Hsu, Yi-Hsiang, Karasik, David, Xiao, Su-Mei, Nielson, Carrie, Srikanth, Priya, Giroux, Sylvie, Wilson, Scott G., Zheng, Hou-Feng, Smith, Albert V., Pye, Stephen R., Teumer, Alexander, Hwang, Joo-Yeon, McGuigan, Fiona, Minster, Ryan L., Lyytikäinen, Leo-Pekka, Swart, Karin M.A., Masi, Laura, Oldmeadow, Chris, Cheng, Sulin, Harvey, Nicholas C., Kruk, Marcin, del Greco M, Fabiola, Igl, Wilmar, Luben, Robert, Liu, Ching-Ti, Oei, Ling, Medina-Gomez, Carolina, Zmuda, Joseph, Tranah, Greg, Brown, Suzanne J., Williams, Frances M., Soranzo, Nicole, Siggeirsdottir, Kristin, Hannemann, Anke, Go, Min Jin, Garcia, Melissa, Polasek, Ozren, Laaksonen, Marika, Zhu, Kun, Enneman, Anke W., McEvoy, Mark, Peel, Roseanne, Sham, Pak Chung, Jaworski, Maciej, Johansson, Åsa, Pludowski, Pawel, Scott, Rodney, Kähönen, Mika, Viikari, Jorma S., Sievänen, Harri, Raitakari, Olli T., Hernández, Jose L., Ljunggren, Östen, Völker, Uwe, Nauck, Matthias, Homuth, Georg, Haring, Robin, McCloskey, Eugene, Eastell, Richard, Jones, Graeme, Reid, Ian R., Dennison, Elaine M., Wark, John, Vanderschueren, Dirk, Aspelund, Thor, Richards, J. Brent, Bauer, Doug, Hofman, Albert, Khaw, Kay-Tee, Dedoussis, George, Obermayer-Pietsch, Barbara, Gyllensten, Ulf, Pramstaller, Peter P., Lorenc, Roman S., Cooper, Cyrus, Kung, Annie Wai Chee, Lips, Paul, Alen, Markku, Attia, John, Brandi, Maria Luisa, de Groot, Lisette C.P.G.M., Lehtimäki, Terho, Riancho, José A., Harris, Tamara B., Akesson, Kristina, Karlsson, Magnus, Lee, Jong-Young, Duncan, Emma L., O'Neill, Terence W., Gudnason, Vilmundur, Spector, Timothy D., Orwoll, Eric, Wareham, Nick J., Rivadeneira, Fernando, Uitterlinden, Andre G., Prince, Richard L., Kiel, Douglas P., Reeve, Jonathan, Kaptoge, Stephen K.

    Veröffentlicht in Human molecular genetics

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