Discovery of Affinity‐Based Probes for Btk Occupancy Assays von Qiu, Hui, Caldwell, Richard, Liu‐Bujalski, Lesley, Goutopoulos, Andreas, Jones, Reinaldo, Potnick, Justin, Sherer, Brian, Bender, Andrew, Grenningloh, Roland, Xu, Daigen, Gardberg, Anna, Mochalkin, Igor, Johnson, Theresa, Viacava Follis, Ariele, Head, Jared, Morandi, Federica

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Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases von Caldwell, Richard D, Qiu, Hui, Askew, Ben C, Bender, Andrew T, Brugger, Nadia, Camps, Montserrat, Dhanabal, Mohanraj, Dutt, Vikram, Eichhorn, Thomas, Gardberg, Anna S, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Healey, Brian, Hodous, Brian L, Huck, Bayard R, Johnson, Theresa L, Jones, Christopher, Jones, Reinaldo C, Mochalkin, Igor, Morandi, Federica, Nguyen, Ngan, Meyring, Michael, Potnick, Justin R, Santos, Dusica Cvetinovic, Schmidt, Ralf, Sherer, Brian, Shutes, Adam, Urbahns, Klaus, Follis, Ariele Viacava, Wegener, Ansgar A, Zimmerli, Simone C, Liu-Bujalski, Lesley

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Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models von Haselmayer, Philipp, Camps, Montserrat, Liu-Bujalski, Lesley, Nguyen, Ngan, Morandi, Federica, Head, Jared, O'Mahony, Alison, Zimmerli, Simone C, Bruns, Lisa, Bender, Andrew T, Schroeder, Patricia, Grenningloh, Roland

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Ability of Bruton’s Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling von Bender, Andrew T., Gardberg, Anna, Pereira, Albertina, Johnson, Theresa, Wu, Yin, Grenningloh, Roland, Head, Jared, Morandi, Federica, Haselmayer, Philipp, Liu-Bujalski, Lesley

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Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit von Qiu, Hui, Liu-Bujalski, Lesley, Caldwell, Richard D, Follis, Ariele Viacava, Gardberg, Anna, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Johnson, Theresa, Jones, Reinaldo, Mochalkin, Igor, Morandi, Federica, Neagu, Constantin, Sherer, Brian

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Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk von Caldwell, Richard, Liu-Bujalski, Lesley, Qiu, Hui, Mochalkin, Igor, Jones, Reinaldo, Neagu, Constantin, Goutopoulos, Andreas, Grenningloh, Roland, Johnson, Theresa, Sherer, Brian, Gardberg, Anna, Follis, Ariele Viacava, Morandi, Federica, Head, Jared

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Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors von Qiu, Hui, Liu-Bujalski, Lesley, Caldwell, Richard D., Viacava Follis, Ariele, Gardberg, Anna, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Johnson, Theresa, Jones, Christopher C.V., Jones, Reinaldo, Mochalkin, Igor, Morandi, Federica, Neagu, Constantin, Potnick, Justin, Sherer, Brian

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SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors von Karra, Srinivasa, Xiao, Yufang, Chen, Xiaoling, Liu-Bujalski, Lesley, Huck, Bayard, Sutton, Amanda, Goutopoulos, Andreas, Askew, Ben, Josephson, Kristopher, Jiang, Xuliang, Shutes, Adam, Shankar, Vikram, Noonan, Tom, Garcia-Berrios, Gaianne, Dong, Rong, Dhanabal, Mohanraj, Tian, Hui, Wang, Zhenxiong, Clark, A., Goodstal, Samantha

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Selective Wee1 Inhibitors Led to Antitumor Activity In Vitro and Correlated with Myelosuppression von Guler, Satenig, DiPoto, Maria C., Crespo, Alejandro, Caldwell, Richard, Doerfel, Benjamin, Grossmann, Nina, Ho, Kevin, Huck, Bayard, Jones, Christopher CV, Lan, Ruoxi, Musil, Djordje, Potnick, Justin, Schilke, Heike, Sherer, Brian, Simon, Stephanie, Sirrenberg, Christian, Zhang, Zhuo, Liu-Bujalski, Lesley

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Btk inhibition treats TLR7/IFN driven murine lupus von Bender, Andrew T, Pereira, Albertina, Fu, Kai, Samy, Eileen, Wu, Yin, Liu-Bujalski, Lesley, Caldwell, Richard, Chen, Yi-Ying, Tian, Hui, Morandi, Federica, Head, Jared, Koehler, Ursula, Genest, Melinda, Okitsu, Shinji L, Xu, Daigen, Grenningloh, Roland

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THIAZOLE AND OXAZOLE COMPOUNDS AS GLYCOSIDASE INHIBITORS von LIU-BUJALSKI, LESLEY, YU, HENRY, JOHNSON, THERESA L

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Pyrimidine derivatives as BTK inhibitors and uses thereof von CALDWELL, Richard D, QIU, Hui, LIU-BUJALSKI, Lesley

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Pyrimidine derivatives as BTK inhibitors and uses thereof von CALDWELL, Richard D, QIU, Hui, LIU-BUJALSKI, Lesley

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Pyrimidine derivatives, their preparation and pharmaceutical compositions containing them von CALDWELL Richard D, LIU-BUJALSKI Lesley, QIU Hui

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FUSED IMIDAZOPYRIDINES AS REVERSIBLE INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) von CALDWELL, Richard D, NEAGU, Constantin, KULKARNI, Shashank, JONES, Reinaldo, POTNICK, Justin, QIU, Hui, LIU-BUJALSKI, Lesley

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PYRIMIDINE DERIVATIVES AS BTK INHIBITORS AND USES THEREOF von CALDWELL, Richard D, QIU, Hui, LIU-BUJALSKI, Lesley

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Pharmaceutical compositions comprising glycosidase inhibitors and their preparation von YU HENRY, LIU-BUJALSKI LESLEY, JOHNSON THERESA L

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PYRIDINES, PYRIMIDINES, AND PYRAZINES, AS BTK INHIBITORS AND USES THEREOF von LIU-BUJALSKI, LESLEY, NGUYEN, NGAN, JONES, REINALDO, MOCHALKIN, IGOR, CALDWELL, RICHARD D, QIU, HUI

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PYRIMIDINE DERIVATIVES AS BTK INHIBITORS AND USES THEREOF von LESLEY LIU-BUJALSKI, HUI QIU, RICHARD D CALDWELL

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Heteroaryl compounds as BTK inhibitors and uses thereof von Liu-Bujalski, Lesley, Caldwell, Richard D, Qiu, Hui

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