The effect of pathophysiology on pharmacokinetics in the critically ill patient — Concepts appraised by the example of antimicrobial agents von Blot, Stijn I., Pea, Federico, Lipman, Jeffrey

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Pharmacokinetic issues for antibiotics in the critically ill patient von Roberts, Jason A, Lipman, Jeffrey

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A meta-analysis of ventriculostomy-associated cerebrospinal fluid infections von Ramanan, Mahesh, Lipman, Jeffrey, Shorr, Andrew, Shankar, Aparna

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Initial antimicrobial management of sepsis von Niederman, Michael S, Baron, Rebecca M, Bouadma, Lila, Calandra, Thierry, Daneman, Nick, DeWaele, Jan, Kollef, Marin H, Lipman, Jeffrey, Nair, Girish B

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Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgery von Alli, Ahmad, Paruk, Fathima, Roger, Claire, Lipman, Jeffrey, Calleemalay, Daren, Wallis, Steven C., Scribante, Juan, Richards, Guy A., Roberts, Jason A.

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Protein Binding of β-Lactam Antibiotics in Critically Ill Patients: Can We Successfully Predict Unbound Concentrations? von Wong, Gloria, Briscoe, Scott, Adnan, Syamhanin, McWhinney, Brett, Ungerer, Jacobus, Lipman, Jeffrey, Roberts, Jason A

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Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care von Myburgh, John A, Finfer, Simon, Bellomo, Rinaldo, Billot, Laurent, Cass, Alan, Gattas, David, Glass, Parisa, Lipman, Jeffrey, Liu, Bette, McArthur, Colin, McGuinness, Shay, Rajbhandari, Dorrilyn, Taylor, Colman B, Webb, Steven A.R

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Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit von Sakr, Yasser, Jaschinski, Ulrich, Wittebole, Xavier, Szakmany, Tamas, Lipman, Jeffrey, Ñamendys-Silva, Silvio A, Martin-Loeches, Ignacio, Leone, Marc, Lupu, Mary-Nicoleta, Vincent, Jean-Louis

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Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions von Roberts, Jason A, Prof, Abdul-Aziz, Mohd H, BPharm, Lipman, Jeffrey, Prof, Mouton, Johan W, Prof, Vinks, Alexander A, Prof, Felton, Timothy W, Dr, Hope, William W, Prof, Farkas, Andras, Dr, Neely, Michael N, MD, Schentag, Jerome J, Dr, Drusano, George, Prof, Frey, Otto R, Dr, Theuretzbacher, Ursula, Dr, Kuti, Joseph L, Dr

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The Effects of Hypoalbuminaemia on Optimizing Antibacterial Dosing in Critically Ill Patients von Ulldemolins, Marta, Roberts, Jason A., Rello, Jordi, Paterson, David L., Lipman, Jeffrey

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A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care Unit von Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-François, Leone, Marc, Zahar, Jean Ralph, De Waele, Jan J.

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Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: A structured review von Alobaid, Abdulaziz S, Hites, Maya, Lipman, Jeffrey, Taccone, Fabio Silvio, Roberts, Jason A

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Toward Improved Surveillance: The Impact of Ventilator-Associated Complications on Length of Stay and Antibiotic Use in Patients in Intensive Care Units von Hayashi, Yoshiro, Morisawa, Kenichiro, Klompas, Michael, Jones, Mark, Bandeshe, Hiran, Boots, Robert, Lipman, Jeffrey, Paterson, David L.

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A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Coho... von McHugh, Leo, Seldon, Therese A, Brandon, Roslyn A, Kirk, James T, Rapisarda, Antony, Sutherland, Allison J, Presneill, Jeffrey J, Venter, Deon J, Lipman, Jeffrey, Thomas, Mervyn R, Klein Klouwenberg, Peter M C, van Vught, Lonneke, Scicluna, Brendon, Bonten, Marc, Cremer, Olaf L, Schultz, Marcus J, van der Poll, Tom, Yager, Thomas D, Brandon, Richard B

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Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended... von Carlier, Mieke, Carrette, Sofie, Roberts, Jason A, Stove, Veronique, Verstraete, Alain, Hoste, Eric, Depuydt, Pieter, Decruyenaere, Johan, Lipman, Jeffrey, Wallis, Steven C, De Waele, Jan J

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Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit von Vincent, Jean-Louis, Prof, Marshall, John C, Prof, Ñamendys-Silva, Silvio A, MD, François, Bruno, Prof, Martin-Loeches, Ignacio, MD, Lipman, Jeffrey, Prof, Reinhart, Konrad, Prof, Antonelli, Massimo, Prof, Pickkers, Peter, MD, Njimi, Hassane, PhD, Jimenez, Edgar, MD, Sakr, Yasser, MD

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A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics von Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo

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The importance of airway and lung microbiome in the critically ill von Martin-Loeches, Ignacio, Dickson, Robert, Torres, Antoni, Hanberger, Håkan, Lipman, Jeffrey, Antonelli, Massimo, de Pascale, Gennaro, Bozza, Fernando, Vincent, Jean Louis, Murthy, Srinivas, Bauer, Michael, Marshall, John, Cilloniz, Catia, Bos, Lieuwe D

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Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study von Tabah, Alexis, Koulenti, Despoina, Laupland, Kevin, Misset, Benoit, Valles, Jordi, Bruzzi de Carvalho, Frederico, Paiva, José Artur, Çakar, Nahit, Ma, Xiaochun, Eggimann, Philippe, Antonelli, Massimo, Bonten, Marc J. M., Csomos, Akos, Krueger, Wolfgang A., Mikstacki, Adam, Lipman, Jeffrey, Depuydt, Pieter, Vesin, Aurélien, Garrouste-Orgeas, Maité, Zahar, Jean-Ralph, Blot, Stijn, Carlet, Jean, Brun-Buisson, Christian, Martin, Claude, Rello, Jordi, Dimopoulos, Georges, Timsit, Jean-François

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A review of -multidrug-resistant Enterobacteriaceae in a neonatal unit in Johannesburg, South Africa von Ballot, Daynia E, Bandini, Rosella, Nana, Trusha, Bosman, Noma, Thomas, Teena, Davies, Victor A, Cooper, Peter A, Mer, Mervyn, Lipman, Jeffrey

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