Immunologic Strategies in Pancreatic Cancer: Making Cold Tumors Hot von Ullman, Nicholas A, Burchard, Paul R, Dunne, Richard F, Linehan, David C

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Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-... von Nywening, Timothy M, MD, Wang-Gillam, Andrea, MD, Sanford, Dominic E, MD, Belt, Brian A, MA, Panni, Roheena Z, MD, Cusworth, Brian M, BA, Toriola, Adetunji T, MD, Nieman, Rebecca K, MS, Worley, Lori A, BS, Yano, Motoyo, MD, Fowler, Kathryn J, MD, Lockhart, A Craig, MD, Suresh, Rama, MD, Tan, Benjamin R, MD, Lim, Kian-Huat, MD, Fields, Ryan C, MD, Strasberg, Steven M, Prof, Hawkins, William G, Prof, DeNardo, David G, PhD, Goedegebuure, S Peter, PhD, Linehan, David C, Dr Prof

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CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models von Zhu, Yu, Knolhoff, Brett L, Meyer, Melissa A, Nywening, Timothy M, West, Brian L, Luo, Jingqin, Wang-Gillam, Andrea, Goedegebuure, S Peter, Linehan, David C, DeNardo, David G

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Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses von MITCHEM, Jonathan B, BRENNAN, Donal J, HEWITT, Stephen, MALLYA UDUPI, Girish, GALLAGHER, William M, WEGNER, Craig, WEST, Brian L, WANG-GILLAM, Andrea, GOEDEGEBUURE, Peter, LINEHAN, David C, DENARDO, David G, KNOLHOFF, Brett L, BELT, Brian A, YU ZHU, SANFORD, Dominic E, BELAYGOROD, Larisa, CARPENTER, Danielle, COLLINS, Lynne, PIWNICA-WORMS, David

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The Accordion Severity Grading System of Surgical Complications von STRASBERG, Steven M, LINEHAN, David C, HAWKINS, William G

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Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance von Meyer, Melissa A., Baer, John M., Knolhoff, Brett L., Nywening, Timothy M., Panni, Roheena Z., Su, Xinming, Weilbaecher, Katherine N., Hawkins, William G., Ma, Cynthia, Fields, Ryan C., Linehan, David C., Challen, Grant A., Faccio, Roberta, Aft, Rebecca L., DeNardo, David G.

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Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma von Nywening, Timothy M, Belt, Brian A, Cullinan, Darren R, Panni, Roheena Z, Han, Booyeon J, Sanford, Dominic E, Jacobs, Ryan C, Ye, Jian, Patel, Ankit A, Gillanders, William E, Fields, Ryan C, DeNardo, David G, Hawkins, William G, Goedegebuure, Peter, Linehan, David C

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Purity Independent Subtyping of Tumors (PurIST), A Clinically Robust, Single-sample Classifier for Tumor Subtyping in Pancreatic Cancer von Rashid, Naim U, Peng, Xianlu L, Jin, Chong, Moffitt, Richard A, Volmar, Keith E, Belt, Brian A, Panni, Roheena Z, Nywening, Timothy M, Herrera, Silvia G, Moore, Kristin J, Hennessey, Sarah G, Morrison, Ashley B, Kawalerski, Ryan, Nayyar, Apoorve, Chang, Audrey E, Schmidt, Benjamin, Kim, Hong Jin, Linehan, David C, Yeh, Jen Jen

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Regional Lymphadenectomy Is Indicated in the Surgical Treatment of Pancreatic Neuroendocrine Tumors (PNETs) von Hashim, Yassar M, Trinkaus, Kathryn M, Linehan, David C, Strasberg, Steven S, Fields, Ryan C, Cao, Dengfeng, Hawkins, William G

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Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis von SANFORD, Dominic E, BELT, Brian A, WANG-GILLAM, Andrea, EBERLEIN, Timothy J, DENARDO, David G, GOEDEGEBUURE, Simon Peter, LINEHAN, David C, PANNI, Roheena Z, MAYER, Allese, DESHPANDE, Anjali D, CARPENTER, Danielle, MITCHEM, Jonathan B, PLAMBECK-SUESS, Stacey M, WORLEY, Lori A, GOETZ, Brian D

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Pretreatment Assessment of Resectable and Borderline Resectable Pancreatic Cancer: Expert Consensus Statement von Callery, Mark P., Chang, Kenneth J., Fishman, Elliot K., Talamonti, Mark S., William Traverso, L., Linehan, David C.

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Composition, Spatial Characteristics, and Prognostic Significance of Myeloid Cell Infiltration in Pancreatic Cancer von Väyrynen, Sara A, Zhang, Jinming, Yuan, Chen, Väyrynen, Juha P, Dias Costa, Andressa, Williams, Hannah, Morales-Oyarvide, Vicente, Lau, Mai Chan, Rubinson, Douglas A, Dunne, Richard F, Kozak, Margaret M, Wang, Wenjia, Agostini-Vulaj, Diana, Drage, Michael G, Brais, Lauren, Reilly, Emma, Rahma, Osama, Clancy, Thomas, Wang, Jiping, Linehan, David C, Aguirre, Andrew J, Fuchs, Charles S, Coussens, Lisa M, Chang, Daniel T, Koong, Albert C, Hezel, Aram F, Ogino, Shuji, Nowak, Jonathan A, Wolpin, Brian M

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Supporting Surgeon-Scientists to Prosper as Researchers von Harman, Jennifer E. B, Linehan, David C, Naganathan, Anusha

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Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth von Porembka, Matthew R., Mitchem, Jonathan B., Belt, Brian A., Hsieh, Chyi-Song, Lee, Hyang-Mi, Herndon, John, Gillanders, William E., Linehan, David C., Goedegebuure, Peter

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Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer von Panni, Roheena Z., Sanford, Dominic E., Belt, Brian A., Mitchem, Jonathan B., Worley, Lori A., Goetz, Brian D., Mukherjee, Pinku, Wang-Gillam, Andrea, Link, Daniel C., DeNardo, David G., Goedegebuure, S. Peter, Linehan, David C.

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Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients von Sausen, Mark, Phallen, Jillian, Adleff, Vilmos, Jones, Siân, Leary, Rebecca J., Barrett, Michael T., Anagnostou, Valsamo, Parpart-Li, Sonya, Murphy, Derek, Kay Li, Qing, Hruban, Carolyn A., Scharpf, Rob, White, James R., O’Dwyer, Peter J., Allen, Peter J., Eshleman, James R., Thompson, Craig B., Klimstra, David S., Linehan, David C., Maitra, Anirban, Hruban, Ralph H., Diaz, Luis A., Von Hoff, Daniel D., Johansen, Julia S., Drebin, Jeffrey A., Velculescu, Victor E.

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Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of meta... von Noel, Marcus, O’Reilly, Eileen M., Wolpin, Brian M., Ryan, David P., Bullock, Andrea J., Britten, Carolyn D., Linehan, David C., Belt, Brian A., Gamelin, Eric C., Ganguly, Bishu, Yin, Donghua, Joh, Tenshang, Jacobs, Ira A., Taylor, Carrie T., Lowery, Maeve A.

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Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer von Grossman, Julie G, Nywening, Timothy M, Belt, Brian A, Panni, Roheena Z, Krasnick, Bradley A, DeNardo, David G, Hawkins, William G, Goedegebuure, S Peter, Linehan, David C, Fields, Ryan C

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Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm von Ruffolo, Luis I., Jackson, Katherine M., Juviler, Peter, Kaur, Roma, Chennell, Todd, Glover, Danielle M., Linehan, David C., Moalem, Jacob

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Lymph node metastases in resected pancreatic ductal adenocarcinoma: predictors of disease recurrence and survival von Morales-Oyarvide, Vicente, Rubinson, Douglas A, Dunne, Richard F, Kozak, Margaret M, Bui, Justin L, Yuan, Chen, Qian, Zhi Rong, Babic, Ana, Da Silva, Annacarolina, Nowak, Jonathan A, Khalaf, Natalia, Brais, Lauren K, Welch, Marisa W, Zellers, Caitlin L, Ng, Kimmie, Chang, Daniel T, Miksad, Rebecca A, Bullock, Andrea J, Tseng, Jennifer F, Swanson, Richard S, Clancy, Thomas E, Linehan, David C, Findeis-Hosey, Jennifer J, Doyle, Leona A, Hornick, Jason L, Ogino, Shuji, Fuchs, Charles S, Hezel, Aram F, Koong, Albert C, Wolpin, Brian M

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