Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity von Liu, Yiliu, Olagnier, David, Lin, Rongtuan

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Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production von Wang, Shuai, Wang, Kezhen, Lin, Rongtuan, Zheng, Chunfu

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Nlrp6 regulates intestinal antiviral innate immunity von Wang, Penghua, Zhu, Shu, Yang, Long, Cui, Shuang, Pan, Wen, Jackson, Ruaidhri, Zheng, Yunjiang, Rongvaux, Anthony, Sun, Qiangming, Yang, Guang, Gao, Shandian, Lin, Rongtuan, You, Fuping, Flavell, Richard, Fikrig, Erol

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Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming von Olagnier, David, Brandtoft, Aske M., Gunderstofte, Camilla, Villadsen, Nikolaj L., Krapp, Christian, Thielke, Anne L., Laustsen, Anders, Peri, Suraj, Hansen, Anne Louise, Bonefeld, Lene, Thyrsted, Jacob, Bruun, Victor, Iversen, Marie B., Lin, Lin, Artegoitia, Virginia M., Su, Chenhe, Yang, Long, Lin, Rongtuan, Balachandran, Siddharth, Luo, Yonglun, Nyegaard, Mette, Marrero, Bernadette, Goldbach-Mansky, Raphaela, Motwani, Mona, Ryan, Dylan G., Fitzgerald, Katherine A., O’Neill, Luke A., Hollensen, Anne K., Damgaard, Christian K., de Paoli, Frank v., Bertram, Hanne C., Jakobsen, Martin R., Poulsen, Thomas B., Holm, Christian K.

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Herpes Simplex Virus 1-Encoded Tegument Protein VP16 Abrogates the Production of Beta Interferon (IFN) by Inhibiting NF-κB Activation and Blocking IFN Regulatory Factor 3 To Recrui... von Xing, Junji, Ni, Liwen, Wang, Shuai, Wang, Kezhen, Lin, Rongtuan, Zheng, Chunfu

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STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer von Totten, Stephanie P., Im, Young Kyuen, Cepeda Cañedo, Eduardo, Najyb, Ouafa, Nguyen, Alice, Hébert, Steven, Ahn, Ryuhjin, Lewis, Kyle, Lebeau, Benjamin, La Selva, Rachel, Sabourin, Valérie, Martínez, Constanza, Savage, Paul, Kuasne, Hellen, Avizonis, Daina, Santos Martínez, Nancy, Chabot, Catherine, Aguilar-Mahecha, Adriana, Goulet, Marie-Line, Dankner, Matthew, Witcher, Michael, Petrecca, Kevin, Basik, Mark, Pollak, Michael, Topisirovic, Ivan, Lin, Rongtuan, Siegel, Peter M., Kleinman, Claudia L., Park, Morag, St-Pierre, Julie, Ursini-Siegel, Josie

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A cell-based assay to discover inhibitors of SARS-CoV-2 RNA dependent RNA polymerase von Zhao, Jianyuan, Guo, SaiSai, Yi, Dongrong, Li, Quanjie, Ma, Ling, Zhang, Yongxin, Wang, Jing, Li, Xiaoyu, Guo, Fei, Lin, Rongtuan, Liang, Chen, Liu, Zhenlong, Cen, Shan

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Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells von Olagnier, David, Peri, Suraj, Steel, Courtney, van Montfoort, Nadine, Chiang, Cindy, Beljanski, Vladimir, Slifker, Michael, He, Zhong, Nichols, Carmen N, Lin, Rongtuan, Balachandran, Siddharth, Hiscott, John

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Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling von Hansen, Anne Louise, Buchan, Gregory J., Rühl, Michael, Mukai, Kojiro, Salvatore, Sonia R., Ogawa, Emari, Andersen, Sidsel D., Iversen, Marie B., Thielke, Anne L., Gunderstofte, Camilla, Motwani, Mona, Møller, Charlotte T., Jakobsen, Andreas S., Fitzgerald, Katherine A., Roos, Jessica, Lin, Rongtuan, Maier, Thorsten J., Goldbach-Mansky, Raphaela, Miner, Cathrine A., Qian, Wei, Miner, Jonathan J., Rigby, Rachel E., Rehwinkel, Jan, Jakobsen, Martin R., Arai, Hiroyuki, Taguchi, Tomohiko, Schopfer, Francisco J., Olagnier, David, Holm, Christian K.

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Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5 von Xing, Junji, Wang, Shuai, Lin, Rongtuan, Mossman, Karen L, Zheng, Chunfu

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Editorial: Sensing DNA in Antiviral Innate Immunity von Lin, Rongtuan, Xing, Junji, Zheng, Chunfu

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UBXN3B positively regulates STING-mediated antiviral immune responses von Yang, Long, Wang, Leilei, Ketkar, Harshada, Ma, Jinzhu, Yang, Guang, Cui, Shuang, Geng, Tingting, Mordue, Dana G., Fujimoto, Toyoshi, Cheng, Gong, You, Fuping, Lin, Rongtuan, Fikrig, Erol, Wang, Penghua

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RIG-I-Mediated STING Upregulation Restricts Herpes Simplex Virus 1 Infection von Liu, Yiliu, Goulet, Marie-Line, Sze, Alexandre, Hadj, Samar Bel, Belgnaoui, Sidi Mehdi, Lababidi, Rassin R, Zheng, Chunfu, Fritz, Jörg Hermann, Olagnier, David, Lin, Rongtuan

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A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response von Paz, Suzanne, Vilasco, Myriam, Werden, Steven J, Arguello, Meztli, Joseph-Pillai, Deshanthe, Zhao, Tiejun, Nguyen, Thi Lien-Anh, Sun, Qiang, Meurs, Eliane F, Lin, Rongtuan, Hiscott, John

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Varicella-Zoster Virus Immediate-Early Protein ORF61 Abrogates the IRF3-Mediated Innate Immune Response through Degradation of Activated IRF3 von Zhu, Huifang, Zheng, Chunfu, Xing, Junji, Wang, Shuai, Li, Shuping, Lin, Rongtuan, Mossman, Karen L

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Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity von Olagnier, David, Lababidi, Rassin R., Hadj, Samar Bel, Sze, Alexandre, Liu, Yiliu, Naidu, Sharadha Dayalan, Ferrari, Matteo, Jiang, Yuan, Chiang, Cindy, Beljanski, Vladimir, Goulet, Marie-Line, Knatko, Elena V., Dinkova-Kostova, Albena T., Hiscott, John, Lin, Rongtuan

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Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists von Chiang, Cindy, Beljanski, Vladimir, Yin, Kevin, Olagnier, David, Ben Yebdri, Fethia, Steel, Courtney, Goulet, Marie-Line, DeFilippis, Victor R, Streblow, Daniel N, Haddad, Elias K, Trautmann, Lydie, Ross, Ted, Lin, Rongtuan, Hiscott, John

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ELF4 is critical for induction of type I interferon and the host antiviral response von You, Fuping, Wang, Penghua, Yang, Long, Yang, Guang, Zhao, Yang O, Qian, Feng, Walker, Wendy, Sutton, Richard, Montgomery, Ruth, Lin, Rongtuan, Iwasaki, Akiko, Fikrig, Erol

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Triggering the Interferon Antiviral Response through an IKK-Related Pathway von Sharma, Sonia, tenOever, Benjamin R., Grandvaux, Nathalie, Zhou, Guo-Ping, Lin, Rongtuan, Hiscott, John

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Anthracyclines inhibit SARS-CoV-2 infection von Wang, Zhen, Pan, Qinghua, Ma, Ling, Zhao, Jianyuan, McIntosh, Fiona, Liu, Zhenlong, Ding, Shilei, Lin, Rongtuan, Cen, Shan, Finzi, Andrés, Liang, Chen

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