81: Oncogenomics of brain tumors: Integrated approaches reveal novel pathomechanisms von Lichter, P

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Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo von Hanna, B S, McClanahan, F, Yazdanparast, H, Zaborsky, N, Kalter, V, Rößner, P M, Benner, A, Dürr, C, Egle, A, Gribben, J G, Lichter, P, Seiffert, M

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Interim clinical outcomes in the collaborative initial glaucoma treatment study comparing initial treatment randomized to medications or surgery von Lichter, Paul R, Musch, David C, Gillespie, Brenda W, Guire, Kenneth E, Janz, Nancy K, Wren, Patricia A, Mills, M.P.H.Richard P

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De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures von Ernst, A, Campos, B, Meier, J, Devens, F, Liesenberg, F, Wolter, M, Reifenberger, G, Herold-Mende, C, Lichter, P, Radlwimmer, B

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Integrated molecular characterization of IDH‐mutant glioblastomas von Korshunov, A., Casalini, B., Chavez, L., Hielscher, T., Sill, M., Ryzhova, M., Sharma, T., Schrimpf, D., Stichel, D., Capper, D., Reuss, D. E., Sturm, D., Absalyamova, O., Golanov, A., Lambo, S., Bewerunge‐Hudler, M., Lichter, P., Herold‐Mende, C., Wick, W., Pfister, S. M., Kool, M., Jones, D. T. W., von Deimling, A., Sahm, F.

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Stem cell characteristics in glioblastoma are maintained by the ecto-nucleotidase E-NPP1 von Bageritz, J, Puccio, L, Piro, R M, Hovestadt, V, Phillips, E, Pankert, T, Lohr, J, Herold-Mende, C, Lichter, P, Goidts, V

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The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer von Thewes, V, Simon, R, Hlevnjak, M, Schlotter, M, Schroeter, P, Schmidt, K, Wu, Y, Anzeneder, T, Wang, W, Windisch, P, Kirchgäßner, M, Melling, N, Kneisel, N, Büttner, R, Deuschle, U, Sinn, H P, Schneeweiss, A, Heck, S, Kaulfuss, S, Hess-Stumpp, H, Okun, J G, Sauter, G, Lykkesfeldt, A E, Zapatka, M, Radlwimmer, B, Lichter, P, Tönjes, M

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Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells von Kawauchi, D, Ogg, R J, Liu, L, Shih, D J H, Finkelstein, D, Murphy, B L, Rehg, J E, Korshunov, A, Calabrese, C, Zindy, F, Phoenix, T, Kawaguchi, Y, Gronych, J, Gilbertson, R J, Lichter, P, Gajjar, A, Kool, M, Northcott, P A, Pfister, S M, Roussel, M F

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Genetics of chronic lymphocytic leukemia: genomic aberrations and VH gene mutation status in pathogenesis and clinical course von STILGENBAUER, S, BULLINGER, L, LICHTER, P, DÖHNER, H

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Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis von Ratnaparkhe, M, Hlevnjak, M, Kolb, T, Jauch, A, Maass, K K, Devens, F, Rode, A, Hovestadt, V, Korshunov, A, Pastorczak, A, Mlynarski, W, Sungalee, S, Korbel, J, Hoell, J, Fischer, U, Milde, T, Kramm, C, Nathrath, M, Chrzanowska, K, Tausch, E, Takagi, M, Taga, T, Constantini, S, Loeffen, J, Meijerink, J, Zielen, S, Gohring, G, Schlegelberger, B, Maass, E, Siebert, R, Kunz, J, Kulozik, A E, Worst, B, Jones, D T, Pfister, S M, Zapatka, M, Lichter, P, Ernst, A

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Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton von Knudsen, P B, Hanna, B, Ohl, S, Sellner, L, Zenz, T, Döhner, H, Stilgenbauer, S, Larsen, T O, Lichter, P, Seiffert, M

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Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain von Stange, D E, Engel, F, Longerich, T, Koo, B K, Koch, M, Delhomme, N, Aigner, M, Toedt, G, Schirmacher, P, Lichter, P, Weitz, J, Radlwimmer, B

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Subgrouping of Burkitt lymphoma variants by DNA methylation is driven by an EBV‐associated epigenotype von Glaser, S., Val, C., Wagener, R., Kretzmer, H., Klapper, W., Hummel, M., Ammerpohl, O., Lichter, P., Burkhardt, B., Trümper, L., Mbulaiteye, S.

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DNA microarray analysis identifies candidate regions and genes in unexplained mental retardation von ENGELS, H, BROCKSCHMIDT, A, WEBER, R. G, HOISCHEN, A, LANDWEHR, C, BOSSE, K, WALLDORF, C, TOEDT, G, RADLWIMMER, B, PROPPING, P, LICHTER, P

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Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components von Ehrbrecht, A, Müller, U, Wolter, M, Hoischen, A, Koch, A, Radlwimmer, B, Actor, B, Mincheva, A, Pietsch, T, Lichter, P, Reifenberger, G, Weber, RG

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Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation von Peterziel, Heike, Müller, Julia, Danner, Andreas, Barbus, Sebastian, Liu, Hai-Kun, Radlwimmer, Bernhard, Pietsch, Torsten, Lichter, Peter, Schütz, Günther, Hess, Jochen, Angel, Peter

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The collaborative initial glaucoma treatment study: Study design, methods, and baseline characteristics of enrolled patients von Musch, David C, Lichter, Paul R, Guire, Kenneth E, Standardi, Carol L

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Further delineation of chromosomal consensus regions in primary mediastinal B-cell lymphomas: an analysis of 37 tumor samples using high-resolution genomic profiling (array-CGH) von WESSENDORF, S, BARTH, T. F. E, SCHWAENEN, C, VIARDOT, A, MUELLER, A, KESTLER, H. A, KOHLHAMMER, H, LICHTER, P, BENTZ, M, DÖHNER, H, MÖLLER, P

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The onset of p53 loss of heterozygosity is differentially induced in various stem cell types and may involve the loss of either allele von Shetzer, Y, Kagan, S, Koifman, G, Sarig, R, Kogan-Sakin, I, Charni, M, Kaufman, T, Zapatka, M, Molchadsky, A, Rivlin, N, Dinowitz, N, Levin, S, Landan, G, Goldstein, I, Goldfinger, N, Pe'er, D, Radlwimmer, B, Lichter, P, Rotter, V, Aloni-Grinstein, R

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Altered miRNA and gene expression in acute myeloid leukemia with complex karyotype identify networks of prognostic relevance von Rücker, F G, Russ, A C, Cocciardi, S, Kett, H, Schlenk, R F, Botzenhardt, U, Langer, C, Krauter, J, Fröhling, S, Schlegelberger, B, Ganser, A, Lichter, P, Zenz, T, Döhner, H, Döhner, K, Bullinger, L

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