Pyrvinium Attenuates Hedgehog Signaling Downstream of Smoothened von BIN LI, LIANG FEI, Dennis, ORTON, Darren, LU HAN, BAOLIN WANG, CAPOBIANCO, Anthony J, ETHAN LEE, ROBBINS, David J, FLAVENY, Colin A, DAHMANE, Nadia, BAUBET, Valérie, ZHIQIANG WANG, FENG BAI, PEI, Xin-Hai, RODRIGUEZ-BIANCO, Jezabel, BRIAN HANG

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Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis von Li, Bin, Flaveny, Colin A, Giambelli, Camilla, Fei, Dennis Liang, Han, Lu, Hang, Brian I, Bai, Feng, Pei, Xin-Hai, Nose, Vania, Burlingame, Oname, Capobianco, Anthony J, Orton, Darren, Lee, Ethan, Robbins, David J

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The Hedgehog signal transduction network von Robbins, David J, Fei, Dennis Liang, Riobo, Natalia A

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The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation von Palangat, Murali, Anastasakis, Dimitrios G, Fei, Dennis Liang, Lindblad, Katherine E, Bradley, Robert, Hourigan, Christopher S, Hafner, Markus, Larson, Daniel R

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Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival von Fei, Dennis Liang, Motowski, Hayley, Chatrikhi, Rakesh, Prasad, Sameer, Yu, Jovian, Gao, Shaojian, Kielkopf, Clara L, Bradley, Robert K, Varmus, Harold

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Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer von Sverrisson, Einar F., M.D, Zens, Michael S., Ph.D, Liang Fei, Dennis, Ph.D, Andrews, Angeline, Ph.D, Schned, Alan, M.D, Robbins, David, Ph.D, Kelsey, Karl T., M.D, Li, Hua, Ph.D, DiRenzo, James, Ph.D, Karagas, Margaret R., Ph.D, Seigne, John D., M.B

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G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling von Ogden, Stacey K., Fei, Dennis Liang, Schilling, Neal S., Ahmed, Yashi F., Hwa, John, Robbins, David J.

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Regulation of GSK3 cellular location by FRAT modulates mTORC1-dependent cell growth and sensitivity to rapamycin von He, Long, Fei, Dennis Liang, Nagiec, Michal J., Mutvei, Anders P., Lamprakis, Andreas, Kim, Bo Yeon, Blenis, John

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Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma von Wang, Zhiqiang, Da Silva, Thiago G, Jin, Ke, Han, Xiaoqing, Ranganathan, Prathibha, Zhu, Xiaoxia, Sanchez-Mejias, Avencia, Bai, Feng, Li, Bin, Fei, Dennis Liang, Weaver, Kelly, Carpio, Rodrigo Vasquez-Del, Moscowitz, Anna E, Koshenkov, Vadim P, Sanchez, Lilly, Sparling, Lynne, Pei, Xin-Hai, Franceschi, Dido, Ribeiro, Afonso, Robbins, David J, Livingstone, Alan S, Capobianco, Anthony J

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The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression von Winterbottom, Emily F, Koestler, Devin C, Fei, Dennis Liang, Wika, Eric, Capobianco, Anthony J, Marsit, Carmen J, Karagas, Margaret R, Robbins, David J

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Hedgehog Signaling Regulates Bladder Cancer Growth and Tumorigenicity von LIANG FEI, Dennis, SANCHEZ-MEJIAS, Avencia, SCHULZ, Wolfgang A, JAY GANDOLFI, A, KARAGAS, Margaret, ZIMMERS, Teresa A, JORDA, Merce, BEJARANO, Pablo, CAPOBIANCO, Anthony J, ROBBINS, David J, ZHIQIANG WANG, FLAVENY, Colin, JUN LONG, SINGH, Samer, RODRIGUEZ-BLANCO, Jezabel, TOKHUNTS, Robert, GIAMBELLI, Camilla, BRIEGEL, Karoline J

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Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity von SINGH, Samer, ZHIQIANG WANG, BRIEGEL, Karoline J, BEJARANO, Pablo A, DMITROVSKY, Ethan, CAPOBIANCO, Anthony J, ROBBINS, David J, LIANG FEI, Dennis, BLACK, Kendall E, GOETZ, John A, TOKHUNTS, Robert, GIAMBELLI, Camilla, RODRIGUEZ-BLANCO, Jezabel, JUN LONG, LEE, Ethan

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Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene U2af1 von Fei, Dennis Liang, Zhen, Tao, Durham, Benjamin, Ferrarone, John, Zhang, Tuo, Garrett, Lisa, Yoshimi, Akihide, Abdel-Wahab, Omar, Bradley, Robert K., Liu, Paul, Varmus, Harold

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In utero arsenic exposure and fetal immune repertoire in a US pregnancy cohort von Nadeau, Kari C, Li, Zhigang, Farzan, Shohreh, Koestler, Devin, Robbins, David, Fei, Dennis Liang, Malipatlolla, Meena, Maecker, Holden, Enelow, Richard, Korrick, Susan, Karagas, Margaret R

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Runx1 Deficiency and MDS-Associated U2af1 Mutation Cooperate for Leukemia Development in a New Mouse Model von Zhen, Tao, Liang Fei, Dennis, Zhao, Ling, Lopez, Guadalupe, Varmus, Harold, Liu, Pu Paul

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Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study von Fei, Dennis Liang, Koestler, Devin C, Li, Zhigang, Giambelli, Camilla, Sanchez-Mejias, Avencia, Gosse, Julie A, Marsit, Carmen J, Karagas, Margaret R, Robbins, David J

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The Hedgehog processing pathway is required for NSCLC growth and survival von Rodriguez-Blanco, J, Schilling, N S, Tokhunts, R, Giambelli, C, Long, J, Liang Fei, D, Singh, S, Black, K E, Wang, Z, Galimberti, F, Bejarano, P A, Elliot, S, Glassberg, M K, Nguyen, D M, Lockwood, W W, Lam, W L, Dmitrovsky, E, Capobianco, A J, Robbins, D J

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Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors von Li, Bin, Orton, Darren, Neitzel, Leif R, Astudillo, Luisana, Shen, Chen, Long, Jun, Chen, Xi, Kirkbride, Kellye C, Doundoulakis, Thomas, Guerra, Marcy L, Zaias, Julia, Fei, Dennis Liang, Rodriguez-Blanco, Jezabel, Thorne, Curtis, Wang, Zhiqiang, Jin, Ke, Nguyen, Dao M, Sands, Laurence R, Marchetti, Floriano, Abreu, Maria T, Cobb, Melanie H, Capobianco, Anthony J, Lee, Ethan, Robbins, David J

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Arsenic Attenuates GLI Signaling, Increasing or Decreasing its Transcriptional Program in a Context-Dependent Manner von Li, Bin, Giambelli, Camilla, Tang, Bo, Winterbottom, Emily, Long, Jun, Jin, Ke, Wang, Zhiqiang, Fei, Dennis Liang, Nguyen, Dao M, Athar, Mohammad, Wang, Baolin, Subbarayan, Pochi R, Wang, Lily, Rai, Priyamvada, Ardalan, Bach, Capobianco, Anthony J, Robbins, David J

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Activation of Hedgehog Signaling by the Environmental Toxicant Arsenic May Contribute to the Etiology of Arsenic-Induced Tumors von FEI, Dennis Liang, HUA LI, KARAGAS, Margaret R, ROBBINS, David J, KOZUL, Courtney D, BLACK, Kendall E, SINGH, Samer, GOSSE, Julie A, DIRENZO, James, MARTIN, Kathleen A, BAOLIN WANG, HAMILTON, Joshua W

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