Convergent Synthesis of a 5HT7/5HT2 Dual Antagonist von Liang, Jimmy T, Deng, Xiaohu, Mani, Neelakandha S

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Practical Synthesis of a Cathepsin S Inhibitor: Route Identification, Purification Strategies, and Serendipitous Discovery of a Crystalline Salt Form von Deng, Xiaohu, Liang, Jimmy T, Peterson, Matthew, Rynberg, Raymond, Cheung, Eugene, Mani, Neelakandha S

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Design of Concise, Scalable Route to a Cholecystokinin 1 (CCK 1) Receptor Antagonist von Liang, Jimmy T, Mani, Neelakandha S, Jones, Todd K

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Regioselective assembly of fused pyrazole-azepine heterocycles: Synthesis of the 5-HT7 antagonist 1-benzy1-3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine von Dvorak, Curt A., Liang, Jimmy, Mani, Neelakandha S., Carruthers, Nicholas

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Identification of benzofuran central cores for the inhibition of leukotriene A4 hydrolase von Eccles, Wendy, Blevitt, Jonathan M., Booker, Jamila N., Chrovian, Christa C., Crawford, Shelby, de Leon, Aimee Rose, Deng, Xiaohu, Fourie, Anne M., Grice, Cheryl A., Herman, Krystal, Karlsson, Lars, Kearney, Aaron M., Lee-Dutra, Alice, Liang, Jimmy, Luna, Rosa, Pippel, Dan, Rao, Navin, Riley, Jason P., Santillán, Alejandro, Savall, Brad, Tanis, Virginia M., Xue, Xiaohua, Young, Arlene L.

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A Practical Synthesis of Regioisomeric 6- and 7-Methoxytetrahydro-3-benzazepines von Liang, Jimmy T, Liu, Jing, Shireman, Brock T, Tran, Vi, Deng, Xiaohu, Mani, Neelakandha S

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Regioselective assembly of fused pyrazole-azepine heterocycles: Synthesis of the 5-HT7 antagonist 1-benzyl-3-(4-chlorophenyl)-1,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepine von Dvorak, Curt A., Liang, Jimmy, Mani, Neelakandha S., Carruthers, Nicholas I.

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Selective Metalation of Functionalized Quinazolines to Enable Discovery and Advancement of Covalent KRAS Inhibitors von Allison, Brett D., Deng, Xiaohu, Li, Lian-Sheng, Liang, Jimmy, Mani, Neelakandha S., Ren, Pingda, Sales, Zachary S.

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Regioselective Synthesis of 4-Nitro- or 4-Chloro-Tetrasubstituted Pyrazoles from Hydrazones and β-Halo-β-nitrostyrenes von Deng, Xiaohu, Liang, Jimmy T., Mani, Neelakandha S.

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4‑Methyl-6,7-dihydro‑4H‑triazolo[4,5‑c]­pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate... von Letavic, Michael A, Savall, Brad M, Allison, Brett D, Aluisio, Leah, Andres, Jose Ignacio, De Angelis, Meri, Ao, Hong, Beauchamp, Derek A, Bonaventure, Pascal, Bryant, Stewart, Carruthers, Nicholas I, Ceusters, Marc, Coe, Kevin J, Dvorak, Curt A, Fraser, Ian C, Gelin, Christine F, Koudriakova, Tatiana, Liang, Jimmy, Lord, Brian, Lovenberg, Timothy W, Otieno, Monicah A, Schoetens, Freddy, Swanson, Devin M, Wang, Qi, Wickenden, Alan D, Bhattacharya, Anindya

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Allyl-Assisted, Cu(I)-Catalyzed Azide–Alkyne Cycloaddition/Allylation Reaction: Assembly of the [1,2,3]Triazolo-4,5,6,7-tetrahydropyridine Core Structure von Deng, Xiaohu, Liang, Jimmy, Allison, Brett B, Dvorak, Curt, McAllister, Heather, Savall, Brad M, Mani, Neelakandha S

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Regioselective Synthesis of 4-Nitro- or 4-Chloro-Tetrasubstituted Pyrazoles from Hydrazones and [beta]-Halo-[beta]-nitrostyrenes von Deng, Xiaohu, Liang, Jimmy T, Mani, Neelakandha S

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4-Methyl-6,7-dihydro-4 H -triazolo[4,5- c ]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidat... von Letavic, Michael A., Savall, Brad M., Allison, Brett D., Aluisio, Leah, Andres, Jose Ignacio, De Angelis, Meri, Ao, Hong, Beauchamp, Derek A., Bonaventure, Pascal, Bryant, Stewart, Carruthers, Nicholas I., Ceusters, Marc, Coe, Kevin J., Dvorak, Curt A., Fraser, Ian C., Gelin, Christine F., Koudriakova, Tatiana, Liang, Jimmy, Lord, Brian, Lovenberg, Timothy W., Otieno, Monicah A., Schoetens, Freddy, Swanson, Devin M., Wang, Qi, Wickenden, Alan D., Bhattacharya, Anindya

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Convergent Synthesis of a 5HT 7 /5HT 2 Dual Antagonist von Liang, Jimmy T., Deng, Xiaohu, Mani, Neelakandha S.

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A Practical Synthesis of Enantiopure 7-Alkoxy-4-aryl-tetrahydroisoquinoline, a Dual Serotonin Reuptake Inhibitor/Histamine H 3 Antagonist von Deng, Xiaohu, Liang, Jimmy T., Liu, Jing, McAllister, Heather, Schubert, Carsten, Mani, Neelakandha S.

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Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase von Eccles, Wendy, Blevitt, Jonathan M, Booker, Jamila N, Chrovian, Christa C, Crawford, Shelby, de Leon, Aimee Rose, Deng, Xiaohu, Fourie, Anne M, Grice, Cheryl A, Herman, Krystal, Karlsson, Lars, Kearney, Aaron M, Lee-Dutra, Alice, Liang, Jimmy, Luna, Rosa, Pippel, Dan, Rao, Navin, Riley, Jason P, Santillán, Alejandro, Savall, Brad, Tanis, Virginia M, Xue, Xiaohua, Young, Arlene L

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RADIOLABELLED MGL PET LIGANDS von Chen, Gang, Huang, Chaofeng, Liang, Jimmy T

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Radiolabelled MGL pet ligands von Chen, Gang, Huang, Chaofeng, Liang, Jimmy T

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Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist von Sircar, Ila, Gudmundsson, Kristjan S, Martin, Richard, Liang, Jimmy, Nomura, Sumihiro, Jayakumar, Honnappa, Teegarden, Bradley R, Nowlin, Dawn M, Cardarelli, Pina M, Mah, Jason R, Connell, Samuel, Griffith, Ronald C, Lazarides, Elias

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RADIOLABELLED MGL PET LIGANDS von HUANG, Chaofeng, LIANG, Jimmy T, CHEN, Gang

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