The Epidermal Growth Factor Receptor Antibody Cetuximab Induces Autophagy in Cancer Cells by Downregulating HIF-1α and Bcl-2 and Activating the Beclin 1/hVps34 Complex von Li, Xinqun, Fan, Zhen

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The association between Parkinson's disease and melanoma von Pan, Tianhong, Li, Xinqun, Jankovic, Joseph

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Cetuximab reverses the Warburg effect by inhibiting HIF-1-regulated LDH-A von Lu, Haiquan, Li, Xinqun, Luo, Zhongguang, Liu, Jie, Fan, Zhen

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Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson’s Disease von Wu, Yuncheng, Li, Xinqun, Zhu, Julie Xiaohong, Xie, Wenjie, Le, Weidong, Fan, Zhen, Jankovic, Joseph, Pan, Tianhong

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Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis von Kim, Michael P, Li, Xinqun, Deng, Jenying, Zhang, Yun, Dai, Bingbing, Allton, Kendra L, Hughes, Tara G, Siangco, Christian, Augustine, Jithesh J, Kang, Ya'an, McDaniel, Joy M, Xiong, Shunbin, Koay, Eugene J, McAllister, Florencia, Bristow, Christopher A, Heffernan, Timothy P, Maitra, Anirban, Liu, Bin, Barton, Michelle C, Wasylishen, Amanda R, Fleming, Jason B, Lozano, Guillermina

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Roles of autophagy in cetuximab-mediated cancer therapy against EGFR von Li, Xinqun, Lu, Yang, Pan, Tianhong, Fan, Zhen

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Neutrophil-lymphocyte ratio predict outcome of upper gastrointestinal bleeding in emergency von Chen, Xinyi, Li, Xinqun, Zhao, Guangju, Xu, Wen

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DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis von Deng, Jenying, Kang, Yaan, Cheng, Chien-Chia, Li, Xinqun, Dai, Bingbing, Katz, Matthew H, Men, Taoyan, Kim, Michael P, Koay, Eugene A, Huang, Huocong, Brekken, Rolf A, Fleming, Jason B

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3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma von Kang, Ya'an, Deng, Jenying, Ling, Jianhua, Li, Xinqun, Chiang, Yi-Ju, Koay, Eugene J, Wang, Huamin, Burks, Jared K, Chiao, Paul J, Hurd, Mark W, Bhutani, Manoop S, Lee, Jeffrey H, Weston, Brian R, Maitra, Anirban, Ikoma, Naruhiko, Tzeng, Ching-Wei D, Lee, Jeffrey E, DePinho, Ronald A, Wolff, Robert A, Pant, Shubham, McAllister, Florencia, Katz, Matthew Hg, Fleming, Jason B, Kim, Michael P

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Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway von Dai, Bingbing, Augustine, Jithesh J., Kang, Ya’an, Roife, David, Li, Xinqun, Deng, Jenying, Tan, Lin, Rusling, Leona A., Weinstein, John N., Lorenzi, Philip L., Kim, Michael P., Fleming, Jason B.

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Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1α and induction of autophagy in SH-SY5Y cells von Wu, Yuncheng, Li, Xinqun, Xie, Wenjie, Jankovic, Joseph, Le, Weidong, Pan, Tianhong

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Recombinant Human Erythropoietin Antagonizes Trastuzumab Treatment of Breast Cancer Cells via Jak2-Mediated Src Activation and PTEN Inactivation von Liang, Ke, Esteva, Francisco J., Albarracin, Constance, Stemke-Hale, Katherine, Lu, Yang, Bianchini, Giampaolo, Yang, Ching-Yi, Li, Yong, Li, Xinqun, Chen, Chun-Te, Mills, Gordon B., Hortobagyi, Gabriel N., Mendelsohn, John, Hung, Mien-Chie, Fan, Zhen

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AMPK-mediated energy homeostasis and associated metabolic effects on cancer cell response and resistance to cetuximab von Li, Xinqun, Lu, Yang, Lu, Haiquan, Luo, Jingtao, Hong, Yun, Fan, Zhen

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Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma von Dai, Bingbing, Roife, David, Kang, Ya'an, Gumin, Joy, Rios Perez, Mayrim V, Li, Xinqun, Pratt, Michael, Brekken, Rolf A, Fueyo-Margareto, Juan, Lang, Frederick F, Fleming, Jason B

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The antiepidermal growth factor receptor monoclonal antibody cetuximab C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial... von Luwor, Rodney B, Lu, Yang, Li, Xinqun, Mendelsohn, John, Fan, Zhen

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Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab von YANG LU, XINQUN LI, KE LIANG, LUWOR, Rodney, SIDDIK, Zahid H, MILLS, Gordon B, MENDELSOHN, John, ZHEN FAN

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Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-... von Lu, Yang, Liang, Ke, Li, Xinqun, Fan, Zhen

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Requirement of hypoxia-inducible factor-1α down-regulation in mediating the antitumor activity of the anti–epidermal growth factor receptor monoclonal antibody cetuximab von Li, Xinqun, Lu, Yang, Liang, Ke, Pan, Tianhong, Mendelsohn, John, Fan, Zhen

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1, 9-Pyrazoloanthrones downregulate HIF-1α and sensitize cancer cells to cetuximab-mediated anti-EGFR therapy von Lu, Yang, Li, Xinqun, Lu, Haiquan, Fan, Zhen

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Antineoplastic effects of auranofin in human pancreatic adenocarcinoma preclinical models von Rios Perez, Mayrim V., Roife, David, Dai, Bingbing, Pratt, Michael, Dobrowolski, Ryszard, Kang, Ya'an, Li, Xinqun, Augustine, Jithesh J., Zielinski, Rafal, Priebe, Waldemar, Fleming, Jason B.

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