Clonal diversity of recurrently mutated genes in myelodysplastic syndromes von Walter, M J, Shen, D, Shao, J, Ding, L, White, B S, Kandoth, C, Miller, C A, Niu, B, McLellan, M D, Dees, N D, Fulton, R, Elliot, K, Heath, S, Grillot, M, Westervelt, P, Link, D C, DiPersio, J F, Mardis, E, Ley, T J, Wilson, R K, Graubert, T A

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Recurrent DNMT3A mutations in patients with myelodysplastic syndromes von Walter, M J, Ding, L, Shen, D, Shao, J, Grillot, M, McLellan, M, Fulton, R, Schmidt, H, Kalicki-Veizer, J, O'Laughlin, M, Kandoth, C, Baty, J, Westervelt, P, DiPersio, J F, Mardis, E R, Wilson, R K, Ley, T J, Graubert, T A

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Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy von Uy, G L, Duncavage, E J, Chang, G S, Jacoby, M A, Miller, C A, Shao, J, Heath, S, Elliott, K, Reineck, T, Fulton, R S, Fronick, C C, O'Laughlin, M, Ganel, L, Abboud, C N, Cashen, A F, DiPersio, J F, Wilson, R K, Link, D C, Welch, J S, Ley, T J, Graubert, T A, Westervelt, P, Walter, M J

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POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature von Fortier, J M, Payton, J E, Cahan, P, Ley, T J, Walter, M J, Graubert, T A

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Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages von SHAPIRO, S. D, KOBAYASHI, D. K, LEY, T. J

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U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing von Okeyo-Owuor, T, White, B S, Chatrikhi, R, Mohan, D R, Kim, S, Griffith, M, Ding, L, Ketkar-Kulkarni, S, Hundal, J, Laird, K M, Kielkopf, C L, Ley, T J, Walter, M J, Graubert, T A

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Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells von Spencer, D H, Young, M A, Lamprecht, T L, Helton, N M, Fulton, R, O'Laughlin, M, Fronick, C, Magrini, V, Demeter, R T, Miller, C A, Klco, J M, Wilson, R K, Ley, T J

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Metalloelastase is Required for Macrophage-Mediated Proteolysis and Matrix Invasion in Mice von Shipley, J. Michael, Wesselschmidt, Robin L., Kobayashi, Dale K., Ley, Timothy J., Shapiro, Steven D.

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Altered myeloid development and acute leukemia in transgenic mice expressing PML-RARα under control of cathepsin G regulatory sequences von GRISOLANO, J. L, WESSELSCHMIDT, R. L, PELICCI, P. G, LEY, T. J

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Primary acute myeloid leukemia cells with IDH1 or IDH2 mutations respond to a DOT1L inhibitor in vitro von Sarkaria, S M, Christopher, M J, Klco, J M, Ley, T J

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Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death von Grossman, William J., Verbsky, James W., Barchet, Winfried, Colonna, Marco, Atkinson, John P., Ley, Timothy J.

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Clonal evolution revealed by whole genome sequencing in a case of primary myelofibrosis transformed to secondary acute myeloid leukemia von Engle, E K, Fisher, D A C, Miller, C A, McLellan, M D, Fulton, R S, Moore, D M, Wilson, R K, Ley, T J, Oh, S T

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LYMPHOCYTE-MEDIATED CYTOTOXICITY von Russell, John H, Ley, Timothy J

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Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation von Graubert, T A, DiPersio, J F, Russell, J H, Ley, T J

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Development of Leukemia in Mice Transgenic for the tax Gene of Human T-Cell Leukemia Virus Type I von Grossman, William J., Kimata, Jason T., Wong, Fen-Hwa, Zutter, Mary, Ley, Timothy J., Ratner, Lee

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The Role of Granzyme B in Murine Models of Acute Graft-Versus-Host Disease and Graft Rejection von Graubert, Timothy A., Russell, John H., Ley, Timothy J.

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Notch signaling in acute promyelocytic leukemia von Grieselhuber, N R, Klco, J M, Verdoni, A M, Lamprecht, T, Sarkaria, S M, Wartman, L D, Ley, T J

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Natural Killer and Lymphokine-Activated Killer Cells Require Granzyme B for the Rapid Induction of Apoptosis in Susceptible Target Cells von Shresta, Sujan, MacIvor, Debra M., Heusel, Jonathan W., Russell, John H., Ley, Timothy J.

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Targeted sequencing informs the evaluation of normal karyotype cytopenic patients for low-grade myelodysplastic syndrome von Duncavage, E J, O'Brien, J, Vij, K, Miller, C A, Chang, G S, Shao, J, Jacoby, M A, Heath, S, Janke, M R, Elliott, K, Fulton, R S, Fronick, C, O'Laughlin, M, Westervelt, P, Ley, T J, Wilson, R K, Walter, M J

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Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3 von Hug, Bruce A., Wesselschmidt, Robin L., Fiering, Steven, Bender, M. A., Epner, Elliot, Groudine, Mark, Ley, Timothy J.

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