IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure–response relationships and points of departure (PoDs) von MacGregor, James T., Frötschl, Roland, White, Paul A., Crump, Kenny S., Eastmond, David A., Fukushima, Shoji, Guérard, Melanie, Hayashi, Makoto, Soeteman-Hernández, Lya G., Kasamatsu, Toshio, Levy, Dan D., Morita, Takeshi, Müller, Lutz, Schoeny, Rita, Schuler, Maik J., Thybaud, Véronique, Johnson, George E.

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A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals von Kirkland, David, Levy, Dan D., LeBaron, Matthew J., Aardema, Marilyn J., Beevers, Carol, Bhalli, Javed, Douglas, George R., Escobar, Patricia A., Farabaugh, Christopher S., Guerard, Melanie, Johnson, George E., Kulkarni, Rohan, Le Curieux, Frank, Long, Alexandra S., Lott, Jasmin, Lovell, David P., Luijten, Mirjam, Marchetti, Francesco, Nicolette, John J., Pfuhler, Stefan, Roberts, Daniel J., Stankowski, Leon F., Thybaud, Veronique, Weiner, Sandy K., Williams, Andrew, Witt, Kristine L., Young, Robert

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Main issues addressed in the 2014–2015 revisions to the OECD Genetic Toxicology Test Guidelines von Thybaud, Veronique, Lorge, Elisabeth, Levy, Dan D., Benthem, Jan, Douglas, George R., Marchetti, Francesco, Moore, Martha M., Schoeny, Rita, Gibbons, Catherine

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Microarray Analysis of Microbial Virulence Factors von CHIZHIKOV, Vladimir, RASOOLY, Avraham, CHUMAKOV, Konstantin, LEVY, Dan D

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Methyleugenol genotoxicity in the Fischer 344 rat using the comet assay and pathway-focused gene expression profiling von Ding, Wei, Levy, Dan D, Bishop, Michelle E, Lyn-Cook Lascelles, E, Kulkarni, Rohan, Chang, Ching-We, Aidoo, Anane, Manjanatha, Mugimane G

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Carcinogenicity of aspartame, methyleugenol, and isoeugenol von Riboli, Elio, Beland, Frederick A, Lachenmeier, Dirk W, Marques, M Matilde, Phillips, David H, Schernhammer, Eva, Afghan, Abdul, Assunção, Ricardo, Caderni, Giovanna, Corton, J Christopher, de Aragão Umbuzeiro, Gisela, de Jong, Daphne, Deschasaux-Tanguy, Melanie, Hodge, Allison, Ishihara, Junko, Levy, Dan D, Mandrioli, Daniele, McCullough, Marjorie L, McNaughton, Sarah A, Morita, Takeshi, Nugent, Anne P, Ogawa, Kumiko, Pandiri, Arun R, Sergi, Consolato M, Touvier, Mathilde, Zhang, Luoping, Benbrahim-Tallaa, Lamia, Chittiboyina, Shirisha, Cuomo, Danila, DeBono, Nathan L, Debras, Charlotte, de Conti, Aline, El Ghissassi, Fatiha, Fontvieille, Emma, Harewood, Rhea, Kaldor, John, Mattock, Heidi, Pasqual, Elisa, Rigutto, Gabrielle, Simba, Hannah, Suonio, Eero, Viegas, Susana, Wedekind, Roland, Schubauer-Berigan, Mary K, Madia, Federica

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Recommended criteria for the evaluation of bacterial mutagenicity data (Ames test) von Levy, Dan D., Zeiger, Errol, Escobar, Patricia A., Hakura, Atsushi, van der Leede, Bas-jan M., Kato, Masayuki, Moore, Martha M., Sugiyama, Kei-ichi

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Current and Future Application of Genetic Toxicity Assays: The Role and Value of In Vitro Mammalian Assays von Elespuru, Rosalie K., Agarwal, Rajiv, Atrakchi, Aisar H., Bigger, C. Anita H., Heflich, Robert H., Jagannath, Devaraya R., Levy, Dan D., Moore, Martha M., Ouyang, Yanli, Robison, Timothy W., Sotomayor, Rene E., Cimino, Michael C., Dearfield, Kerry L.

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The science and regulations of probiotic food and supplement product labeling von Sanders, Mary Ellen, Levy, Dan D.

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Demonstrating laboratory proficiency in bacterial mutagenicity assays for regulatory submission von Levy, Dan D., Hakura, Atsushi, Elespuru, Rosalie K., Escobar, Patricia A., Kato, Masayuki, Lott, Jasmin, Moore, Martha M., Sugiyama, Kei-ichi

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Single-Nucleotide Polymorphism Mutation Spectra and Resistance to Quinolones in Salmonella enterica Serovar Enteritidis with a Mutator Phenotype von LEVY, Dan D, SHARMA, Bhavana, CEBULA, Thomas A

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Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT) von Speit, Günter, Kojima, Hajime, Burlinson, Brian, Collins, Andrew R., Kasper, Peter, Plappert-Helbig, Ulla, Uno, Yoshifumi, Vasquez, Marie, Beevers, Carol, De Boeck, Marlies, Escobar, Patricia A., Kitamoto, Sachiko, Pant, Kamala, Pfuhler, Stefan, Tanaka, Jin, Levy, Dan D.

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William Gary Flamm (1935–2017) von Green, Sidney, Levy, Dan D., Lorentzen, Ronald J., Zeiger, Errol, Gollapudi, B.

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Revisiting the bacterial mutagenicity assays: Report by a workgroup of the International Workshops on Genotoxicity Testing (IWGT) von Schoeny, Rita, Cross, Kevin P., DeMarini, David M., Elespuru, Rosalie, Hakura, Atsushi, Levy, Dan D., Williams, Richard V., Zeiger, Errol, Escobar, Patricia A., Howe, Jonathan R., Kato, Masayuki, Lott, Jasmin, Moore, Martha M., Simon, Stephanie, Stankowski, Leon F., Sugiyama, Kei-ichi, van der Leede, Bas-jan M.

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Workshop summary: Top concentration for in vitro mammalian cell genotoxicity assays; and report from working group on toxicity measures and top concentration for in vitro cytogenet... von Galloway, Sheila, Lorge, Elisabeth, Aardema, Marilyn J., Eastmond, David, Fellows, Mick, Heflich, Robert, Kirkland, David, Levy, Dan D., Lynch, Anthony M., Marzin, Daniel, Morita, Takeshi, Schuler, Maik, Speit, Günter

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Evaluation of the highest concentrations used in the in vitro chromosome aberrations assay von Brookmire, Lauren, Chen, James J., Levy, Dan D.

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IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk von MacGregor, James T., Frötschl, Roland, White, Paul A., Crump, Kenny S., Eastmond, David A., Fukushima, Shoji, Guérard, Melanie, Hayashi, Makoto, Soeteman-Hernández, Lya G., Johnson, George E., Kasamatsu, Toshio, Levy, Dan D., Morita, Takeshi, Müller, Lutz, Schoeny, Rita, Schuler, Maik J., Thybaud, Véronique

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Safety assessment of probiotics for human use von Sanders, Mary Ellen, Akkermans, Louis M.A., Haller, Dirk, Hammerman, Cathy, Heimbach, James T., Hörmannsperger, Gabriele, Huys, Geert

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In vivo genotoxicity of estragole in male F344 rats von Ding, Wei, Levy, Dan D., Bishop, Michelle E., Pearce, Mason G., Davis, Kelly J., Jeffrey, Alan M., Duan, Jian-Dong, Williams, Gary M., White, Gene A., Lyn-Cook, Lascelles E., Manjanatha, Mugimane G.

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Follow-up actions from positive results of in vitro genetic toxicity testing von Dearfield, Kerry L, Thybaud, Véronique, Cimino, Michael C, Custer, Laura, Czich, Andreas, Harvey, James S, Hester, Susan, Kim, James H, Kirkland, David, Levy, Dan D, Lorge, Elisabeth, Moore, Martha M, Ouédraogo-Arras, Gladys, Schuler, Maik, Suter, Willi, Sweder, Kevin, Tarlo, Kirk, van Benthem, Jan, van Goethem, Freddy, Witt, Kristine L

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