Safety and pharmacokinetics of anti‐TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial von Chowdary, P., Lethagen, S., Friedrich, U., Brand, B., Hay, C., Abdul Karim, F., Klamroth, R., Knoebl, P., Laffan, M., Mahlangu, J., Miesbach, W., Dalsgaard Nielsen, J., Martín‐Salces, M., Angchaisuksiri, P.

Volltext

A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM‐1 VWD) von TOSETTO, A., RODEGHIERO, F., CASTAMAN, G., GOODEVE, A., FEDERICI, A. B., BATLLE, J., MEYER, D., FRESSINAUD, E., MAZURIER, C., GOUDEMAND, J., EIKENBOOM, J., SCHNEPPENHEIM, R., BUDDE, U., INGERSLEV, J., VORLOVA, Z., HABART, D., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.

Volltext

The discriminant power of bleeding history for the diagnosis of type 1 von Willebrand disease: an international, multicenter study von RODEGHIERO, F., CASTAMAN, G., TOSETTO, A., BATLLE, J., BAUDO, F., CAPPELLETTI, A., CASANA, P., DE BOSCH, N., EIKENBOOM, J. C. J., FEDERICI, A. B., LETHAGEN, S., LINARI, S., SRIVASTAVA, A.

Volltext

von Willebrand factor-factor VIII concentrate (Haemate super( registered ) P) dosing based on pharmacokinetics: a prospective multicenter trial in elective surgery von Lethagen, S, Kyrle, P A, Castaman, G, Haertel, S, Mannucci, P M

Volltext

European retrospective study of real‐life haemophilia treatment von Berntorp, E., Dolan, G., Hay, C., Linari, S., Santagostino, E., Tosetto, A., Castaman, G., Álvarez‐Román, MT, Parra Lopez, R., Oldenburg, J., Albert, T., Scholz, U., Holmström, M., Schved, J.‐F., Trossaërt, M., Hermans, C., Boban, A., Ludlam, C., Lethagen, S.

Volltext

Indirect comparisons of efficacy and weekly factor consumption during continuous prophylaxis with recombinant factor VIII Fc fusion protein and conventional recombinant factor VIII... von Iorio, A., Krishnan, S., Myrén, K.J., Lethagen, S., McCormick, N., Yermakov, S., Karner, P.

Volltext

Dosing regimens, FVIII levels and estimated haemostatic protection with special focus on rFVIIIFc von Berntorp, E., Negrier, C., Gozzi, P., Blaas, P-M., Lethagen, S.

Volltext

Detailed von Willebrand factor multimer analysis in patients with von Willebrand disease in the European study, molecular and clinical markers for the diagnosis and management of t... von BUDDE, U., SCHNEPPENHEIM, R., EIKENBOOM, J., GOODEVE, A., WILL, K., DREWKE, E., CASTAMAN, G., RODEGHIERO, F., FEDERICI, A. B., BATLLE, J., PÉREZ, A., MEYER, D., MAZURIER, C., GOUDEMAND, J., INGERSLEV, J., HABART, D., VORLOVA, Z., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.

Volltext

von Willebrand factor/factor VIII concentrate (Haemate® P) dosing based on pharmacokinetics: a prospective multicenter trial in elective surgery von LETHAGEN, S., KYRLE, P. A., CASTAMAN, G., HAERTEL, S., MANNUCCI, P. M.

Volltext

Functional characteristics of N8, a new recombinant FVIII von CHRISTIANSEN, M. L. S., BALLING, K. W., PERSSON, E., HILDEN, I., BAGGER-SØRENSEN, A., SØRENSEN, B. B., VIUFF, D., SEGEL, S., KLAUSEN, N. K., EZBAN, M., LETHAGEN, S., STEENSTRUP, T. D., KJALKE, M.

Volltext

Long-standing prophylactic therapy vs. episodic treatment in young people with severe haemophilia: a comparison of age-matched Danish and Russian patients von Ingerslev, J., Lethagen, S., Hvitfeldt Poulsen, L., Sørensen, B., Lopatina, E., Tentsova, I., Yastrubinetskaya, O., Plyushch, O. P.

Volltext

A comparative in vitro evaluation of six von Willebrand factor concentrates von Lethagen, S., Carlson, M., Hillarp, A.

Volltext

Linkage analysis in families diagnosed with type 1 von Willebrand disease in the European study, molecular and clinical markers for the diagnosis and management of type 1 VWD von EIKENBOOM, J., VAN MARION, V., PUTTER, H., GOODEVE, A., RODEGHIERO, F., CASTAMAN, G., FEDERICI, A. B., BATLLE, J., MEYER, D., MAZURIER, C., GOUDEMAND, J., SCHNEPPENHEIM, R., BUDDE, U., INGERSLEV, J., VORLOVA, Z., HABART, D., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.

Volltext

Safety and pharmacokinetics of subcutaneously administered recombinant activated factor VII (rFVIIa) von TIEDE, A., FRIEDRICH, U., STENMO, C., ALLEN, G., GIANGRANDE, P., GOUDEMAND, J., HAY, C., HOLMSTRÖM, M., KLAMROTH, R., LETHAGEN, S., MCKENZIE, S., MIESBACH, W., NEGRIER, C., YUSTE, V. J., BERNTORP, E.

Volltext

Expression of 14 von Willebrand factor mutations identified in patients with type 1 von Willebrand disease from the MCMDM‐1VWD study von EIKENBOOM, J., HILBERT, L, RIBBA, A. S., HOMMAIS, A., HABART, D., MESSENGER, S., AL‐BUHAIRAN, A., GUILLIATT, A., LESTER, W., MAZURIER, C., MEYER, D., FRESSINAUD, E., BUDDE, U., WILL, K., SCHNEPPENHEIM, R., OBSER, T., MARGGRAF, O., ECKERT, E., CASTAMAN, G., RODEGHIERO, F., FEDERICI, A. B., BATLLE, J., GOUDEMAND, J., INGERSLEV, J., LETHAGEN, S., HILL, F., PEAKE, I., GOODEVE, A.

Volltext

Presurgical pharmacokinetic analysis of a von Willebrand factor/factor VIII (VWF/FVIII) concentrate in patients with von Willebrand's disease (VWD) has limited value in dosing for... von DI PAOLA, J., LETHAGEN, S., GILL, J., MANNUCCI, P., MANCO-JOHNSON, M., BERNSTEIN, J., NICHOLS, W. L., BERGMAN, G. E.

Volltext

No Increased Risk of Venous Thrombosis in Women Taking Tranexamic Acid von Berntorp, Erik, Follrud, Christina, Lethagen, Stefan

Volltext

Hemorrhagic symptoms and bleeding risk in obligatory carriers of type 3 von Willebrand disease: an international, multicenter study von CASTAMAN, G., RODEGHIERO, F., TOSETTO, A., CAPPELLETTI, A., BAUDO, F., EIKENBOOM, J. C. J., FEDERICI, A. B., LETHAGEN, S., LINARI, S., LUSHER, J., NISHINO, M., PETRINI, P., SRIVASTAVA, A., UNGERSTEDT, J. S.

Volltext

Desmopressin - a haemostatic drug: state-of-the-art review von Lethagen, S

Volltext

Impact of plasma von Willebrand factor levels in the diagnosis of type 1 von Willebrand disease: results from a multicenter European study (MCMDM‐1VWD) von TOSETTO, A., RODEGHIERO, F., CASTAMAN, G., BERNARDI, M., BERTONCELLO, K., GOODEVE, A., FEDERICI, A. B., BATLLE, J., MEYER, D., MAZURIER, C., GOUDEMAND, J., EIKENBOOM, J., SCHNEPPENHEIM, R., BUDDE, U., INGERSLEV, J., VORLOVA, Z., HABART, D., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.

Volltext