Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo von Sebolt-Leopold, Judith S, Dudley, David T, Herrera, Roman, Becelaere, Keri Van, Wiland, Amy, Gowan, Richard C, Tecle, Haile, Barrett, Stephen D, Bridges, Alexander, Przybranowski, Sally, Leopold, W.R, Saltiel, Alan R

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A Specific Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase von Fry, David W., Kraker, Alan J., McMichael, Amy, Ambroso, Linda A., Nelson, James M., Leopold, Wilbur R., Conners, Richard W., Bridges, Alexander J.

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Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[d]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Gr... von Smaill, Jeff B, Palmer, Brian D, Rewcastle, Gordon W, Denny, William A, McNamara, Dennis J, Dobrusin, Ellen M, Bridges, Alexander J, Zhou, Hairong, Showalter, H. D. Hollis, Winters, R. Thomas, Leopold, Wilbur R, Fry, David W, Nelson, James M, Slintak, Veronika, Elliot, William L, Roberts, Billy J, Vincent, Patrick W, Patmore, Sandra J

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Radiosensitization of p53 mutant cells by PD0166285, a novel G(2) checkpoint abrogator von Wang, Y, Li, J, Booher, R N, Kraker, A, Lawrence, T, Leopold, W R, Sun, Y

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3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and Related 2-Urea Derivatives Are Potent and Selective Inhibitors of the FGF Receptor-1 Tyrosine Kinase von Thompson, Andrew M, Connolly, Cleo J. C, Hamby, James M, Boushelle, Stacey, Hartl, Brian G, Amar, Aneesa M, Kraker, Alan J, Driscoll, Denise L, Steinkampf, Randall W, Patmore, Sandra J, Vincent, Patrick W, Roberts, Bill J, Elliott, William L, Klohs, Wayne, Leopold, Wilbur R, Showalter, H. D. Hollis, Denny, William A

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Specific, Irreversible Inactivation of the Epidermal Growth Factor Receptor and erbB2, by a New Class of Tyrosine Kinase Inhibitor von Fry, David W., Bridges, Alexander J., Denny, William A., Doherty, Annette, Greis, Kenneth D., Hicks, James L., Hook, Kenneth E., Keller, Paul R., Leopold, Wilbur R., Loo, Joseph A., McNamara, Dennis J., Nelson, James M., Sherwood, Veronika, Smaill, Jeff B., Trumpp-Kallmeyer, Susanne, Dobrusin, Ellen M.

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Cell cycle and biochemical effects of PD 0183812. A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6 von Fry, D W, Bedford, D C, Harvey, P H, Fritsch, A, Keller, P R, Wu, Z, Dobrusin, E, Leopold, W R, Fattaey, A, Garrett, M D

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Anticancer efficacy of the irreversible EGFr tyrosine kinase inhibitor PD 0169414 against human tumor xenografts von VINCENT, P. W, BRIDGES, A. J, ELLIOTT, W. L, DYKES, D. J, FRY, D. W, LEOPOLD, W. R, PATMORE, S. J, ROBERTS, B. J, ROSE, S, SHERWOOD, V, HAIRONG ZHOU

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Inhibition of the epidermal growth factor receptor tyrosine kinase by PD153035 in human A431 tumors in athymic nude mice von KUNKEL, M. W, HOOK, K. E, HOWARD, C. T, PRZYBANOWSKI, S, ROBERTS, B. J, ELLIOTT, W. L, LEOPOLD, W. R

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Chemotherapy with [SP-4-3-(R)]-[1,1-cyclobutanedicarboxylato(2)](2-methyl-1,4-butanediamine-N,N')platinum (CI-973, NK121) in combination with standard agents against murine tumors... von ELLIOTT, W. L, ROBERTS, B. J, HOWARD, C. T, LEOPOLD, W. R

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Differential Utilization and Localization of ErbB Receptor Tyrosine Kinases in Skin Compared to Normal and Malignant Keratinocytes von Stoll, Stefan W., Kansra, Sanjay, Peshick, Scott, Fry, David W., Leopold, Wilbur R., Wiesen, Jane F., Sibilia, Maria, Zhang, Tong, Werb, Zena, Derynck, Rik, Wagner, Erwin F., Elder, James T.

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Induction and chemotherapeutic response of two transplantable ductal adenocarcinomas of the pancreas in C57BL/6 mice von CORBETT, T. H, ROBERTS, B. J, LEOPOLD, W. R, PECKHAM, J. C, WILKOFF, L. J, GRISWOLD, D. P. JR, SCHABEL, F. M. JR

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Preclinical antitumor activity of CI-994 von MUCCI LORUSSO, P, DEMCHIK, L, FOSTER, B, KNIGHT, J, BISSERY, M.-C, POLIN, L. M, LEOPOLD, W. R, CORBETT, T. H

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Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts von Fry, David W, Harvey, Patricia J, Keller, Paul R, Elliott, William L, Meade, Maryanne, Trachet, Erin, Albassam, Mudher, Zheng, XianXian, Leopold, Wilbur R, Pryer, Nancy K, Toogood, Peter L

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In vivo and in vitro evaluation of the alkylating agent carmethizole von ELLIOTT, W. L, FRY, D. W, ANDERSON, W. K, NELSON, J. M, HOOK, K. E, HAWKINS, P. A, LEOPOLD, W. R

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Inhibition of 5-phosphoribosyl-1-pyrophosphate synthetase by the monophosphate metabolite of 4-amino-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine: a novel mechanism for a... von FRY, D. W, BORITZKI, T. J, JACKSON, R. C, COOK, P. D, LEOPOLD, W. R

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Comparative molecular field analysis of in vitro growth inhibition of L1210 and HCT-8 cells by some pyrazoloacridines von Horwitz, Jerome P, Massova, Irina, Wiese, Thomas E, Wozniak, Antoinette J, Corbett, Thomas H, Sebolt-Leopold, Judith S, Capps, David B, Leopold, Wilbur R

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Anthrapyrazoles, a new class of intercalating agents with high-level, broad spectrum activity against murine tumors von LEOPOLD, W. R, NELSON, J. M, PLOWMAN, J, JACKSON, R. C

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Cellular transport of CI-980 von HOOK, K. E, PRZYBRANOWSKI, S. A, LEOPOLD, W. R

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Antitumor efficacy of PD115934 (NSC 366140) against solid tumors of mice von LORUSSO, P, WOZNIAK, A. J, POLIN, L, CAPPS, D, LEOPOLD W. R, WERBEL, L. M, BIERNAT, L, DAN, M. E, CORBETT, T. H

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