Molecular engineering and design of therapeutic antibodies von Presta, Leonard G

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Engineering of therapeutic antibodies to minimize immunogenicity and optimize function von Presta, Leonard G.

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TCR mimic compounds for pHLA targeting with high potency modalities in oncology von Gerber, Hans-Peter, Presta, Leonard G.

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Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease von Petkova, Stefka B., Akilesh, Shreeram, Sproule, Thomas J., Christianson, Gregory J., Al Khabbaz, Hana, Brown, Aaron C., Presta, Leonard G., Meng, Y. Gloria, Roopenian, Derry C.

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Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets von Clynes, Raphael A., Towers, Terri L., Presta, Leonard G., Ravetch, Jeffrey V.

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Selection, design, and engineering of therapeutic antibodies von Presta, Leonard G.

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Anaphylaxis caused by repetitive doses of a GITR agonist monoclonal antibody in mice von Murphy, Judith T., Burey, Andre P., Beebe, Amy M., Gu, Danling, Presta, Leonard G., Merghoub, Taha, Wolchok, Jedd D.

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An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity von Weisser, Nina E., Sanches, Mario, Escobar-Cabrera, Eric, O’Toole, Jason, Whalen, Elizabeth, Chan, Peter W. Y., Wickman, Grant, Abraham, Libin, Choi, Kate, Harbourne, Bryant, Samiotakis, Antonios, Rojas, Andrea Hernández, Volkers, Gesa, Wong, Jodi, Atkinson, Claire E., Baardsnes, Jason, Worrall, Liam J., Browman, Duncan, Smith, Emma E., Baichoo, Priya, Cheng, Chi Wing, Guedia, Joy, Kang, Sohyeong, Mukhopadhyay, Abhishek, Newhook, Lisa, Ohrn, Anders, Raghunatha, Prajwal, Zago-Schmitt, Matteo, Schrag, Joseph D., Smith, Joel, Zwierzchowski, Patricia, Scurll, Joshua M., Fung, Vincent, Black, Sonia, Strynadka, Natalie C. J., Gold, Michael R., Presta, Leonard G., Ng, Gordon, Dixit, Surjit

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Isomerization of an Aspartic Acid Residue in the Complementarity-Determining Regions of a Recombinant Antibody to Human IgE:  Identification and Effect on Binding Affinity von Cacia, Jerry, Keck, Rodney, Presta, Leonard G, Frenz, John

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Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders von PRESTA, L. G, CHEN, H, O'CONNOR, S. J, CHISHOLM, V, MENG, Y. G, KRUMMEN, L, WINKLER, M, FERRARA, N

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Helix Signals in Proteins von Presta, Leonard G., Rose, George D.

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Mapping of the C1q Binding Site on Rituxan, a Chimeric Antibody with a Human IgG1 Fc von Idusogie, Esohe E, Presta, Leonard G, Gazzano-Santoro, Helene, Totpal, Klara, Wong, Pin Yee, Ultsch, Mark, Meng, Y. Gloria, Mulkerrin, Michael G

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Engineered Antibodies with Increased Activity to Recruit Complement von Idusogie, Esohe E, Wong, Pin Yee, Presta, Leonard G, Gazzano-Santoro, Helene, Totpal, Klara, Ultsch, Mark, Mulkerrin, Michael G

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Identification of IgG(1) variants with increased affinity to FcγRIIIa and unaltered affinity to FcγRI and FcRn: comparison of soluble receptor-based and cell-based binding assays von Lu, Yanmei, Vernes, Jean-Michel, Chiang, Nancy, Ou, Qinglin, Ding, Jiabing, Adams, Camellia, Hong, Kyu, Truong, Bao-Tran, Ng, Domingos, Shen, Amy, Nakamura, Gerald, Gong, Qian, Presta, Leonard G, Beresini, Maureen, Kelley, Bob, Lowman, Henry, Wong, Wai Lee, Meng, Y Gloria

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Identification of IgG1 variants with increased affinity to FcγRIIIa and unaltered affinity to FcγRI and FcRn: Comparison of soluble receptor-based and cell-based binding assays von Lu, Yanmei, Vernes, Jean-Michel, Chiang, Nancy, Ou, Qinglin, Ding, Jiabing, Adams, Camellia, Hong, Kyu, Truong, Bao-Tran, Ng, Domingos, Shen, Amy, Nakamura, Gerald, Gong, Qian, Presta, Leonard G., Beresini, Maureen, Kelley, Bob, Lowman, Henry, Wong, Wai Lee, Meng, Y. Gloria

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Comprehensive Functional Maps of the Antigen-binding Site of an Anti-ErbB2 Antibody Obtained with Shotgun Scanning Mutagenesis von Vajdos, Felix F, Adams, Camellia W, Breece, Timothy N, Presta, Leonard G, de Vos, Abraham M, Sidhu, Sachdev S

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Antibody Humanization Using Monovalent Phage Display von Baca, M, Presta, L G, O'Connor, S J, Wells, J A

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Lack of Fucose on Human IgG1 N-Linked Oligosaccharide Improves Binding to Human FcγRIII and Antibody-dependent Cellular Toxicity von Shields, Robert L., Lai, Jadine, Keck, Rodney, O'Connell, Lori Y., Hong, Kyu, Meng, Y. Gloria, Weikert, Stefanie H.A., Presta, Leonard G.

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Simple quantitative live cell and anti-idiotypic antibody based ELISA for humanized antibody directed to cell surface protein CD20 von Hong, Kyu, Presta, Leonard G., Lu, Yanmei, Penn, Ashley, Adams, Camellia, Chuntharapai, Anan, Yang, Jihong, Wong, Wai Lee, Meng, Y. Gloria

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Remodeling domain interfaces to enhance heterodimer formation von Zhu, Zhenping, Presta, Leonard G., Zapata, Gerardo, Carter, Paul

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