The Response of Autologous T Cells to a Human Melanoma is Dominated by Mutated Neoantigens von Volker Lennerz, Martina Fatho, Chiara Gentilini, Frye, Roy A., Alexander Lifke, Dorothea Ferel, Wölfel, Catherine, Huber, Christoph, Wölfel, Thomas, Old, Lloyd J.

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Targeting the melanoma-associated antigen CSPG4 with HLA-C07:01-restricted T-cell receptors von Kropp, Korbinian N., Fatho, Martina, Huduti, Enes, Faust, Marilena, Lübcke, Silke, Lennerz, Volker, Paschen, Annette, Theobald, Matthias, Wölfel, Thomas, Wölfel, Catherine

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How Soluble GARP Enhances TGFβ Activation von Fridrich, Sven, Hahn, Susanne A, Linzmaier, Marion, Felten, Matthias, Zwarg, Jenny, Lennerz, Volker, Tuettenberg, Andrea, Stöcker, Walter

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A key role of GARP in the immune suppressive tumor microenvironment von Hahn, Susanne A, Neuhoff, Annemarie, Landsberg, Jenny, Schupp, Jonathan, Eberts, Daniela, Leukel, Petra, Bros, Matthias, Weilbaecher, Martin, Schuppan, Detlef, Grabbe, Stephan, Tueting, Thomas, Lennerz, Volker, Sommer, Clemens, Jonuleit, Helmut, Tuettenberg, Andrea

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Evolution of melanoma cross-resistance to CD8+ T cells and MAPK inhibition in the course of BRAFi treatment von Pieper, Natalia, Zaremba, Anne, Leonardelli, Sonia, Harbers, Franziska Noelle, Schwamborn, Marion, Lübcke, Silke, Schrörs, Barbara, Baingo, Jolanthe, Schramm, Alexander, Haferkamp, Sebastian, Seifert, Ulrike, Sucker, Antje, Lennerz, Volker, Wölfel, Thomas, Schadendorf, Dirk, Schilling, Bastian, Paschen, Annette, Zhao, Fang

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Exome Sequencing to Predict Neoantigens in Melanoma von Pritchard, Antonia L, Burel, Julie G, Neller, Michelle A, Hayward, Nicholas K, Lopez, J Alejandro, Fatho, Martina, Lennerz, Volker, Wölfel, Thomas, Schmidt, Christopher W

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NPM-ALK-reactive T-cell responses in children and adolescents with NPM-ALK positive anaplastic large cell lymphoma von Singh, Vijay Kumar, Werner, Sebastian, Schwalm, Simone, Lennerz, Volker, Ruf, Stephanie, Stadler, Serena, Hackstein, Holger, Reiter, Alfred, Wölfel, Thomas, Damm-Welk, Christine, Woessmann, Wilhelm

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Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation von Landsberg, Jennifer, Kohlmeyer, Judith, Renn, Marcel, Bald, Tobias, Rogava, Meri, Cron, Mira, Fatho, Martina, Lennerz, Volker, Wölfel, Thomas, Hölzel, Michael, Tüting, Thomas

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Genetic evolution of T-cell resistance in the course of melanoma progression von Sucker, Antje, Zhao, Fang, Real, Birgit, Heeke, Christina, Bielefeld, Nicola, Maβen, Stefan, Horn, Susanne, Moll, Iris, Maltaner, Raffaela, Horn, Peter A, Schilling, Bastian, Sabbatino, Francesco, Lennerz, Volker, Kloor, Matthias, Ferrone, Soldano, Schadendorf, Dirk, Falk, Christine S, Griewank, Klaus, Paschen, Annette

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Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency von Zhao, Fang, Sucker, Antje, Horn, Susanne, Heeke, Christina, Bielefeld, Nicola, Schrörs, Barbara, Bicker, Anne, Lindemann, Monika, Roesch, Alexander, Gaudernack, Gustav, Stiller, Mathias, Becker, Jürgen C, Lennerz, Volker, Wölfel, Thomas, Schadendorf, Dirk, Griewank, Klaus, Paschen, Annette

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Immunologic response to the survivin-derived multi-epitope vaccine EMD640744 in patients with advanced solid tumors von Lennerz, Volker, Gross, Stefanie, Gallerani, Elisa, Sessa, Cristiana, Mach, Nicolas, Boehm, Steffen, Hess, Dagmar, von Boehmer, Lotta, Knuth, Alexander, Ochsenbein, Adrian F., Gnad-Vogt, Ulrike, Zieschang, Juergen, Forssmann, Ulf, Woelfel, Thomas, Kaempgen, Eckhart

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Generation of CD8+ T cells expressing two additional T-cell receptors (TETARs) for personalised melanoma therapy von Höfflin, Sandra, Prommersberger, Sabrina, Uslu, Ugur, Schuler, Gerold, Schmidt, Christopher W, Lennerz, Volker, Dörrie, Jan, Schaft, Niels

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HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model von Schrörs, Barbara, Lübcke, Silke, Lennerz, Volker, Fatho, Martina, Bicker, Anne, Wölfel, Catherine, Derigs, Patrick, Hankeln, Thomas, Schadendorf, Dirk, Paschen, Annette, Wölfel, Thomas

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Gamma Irradiation Triggers Immune Escape in Glioma-Propagating Cells von Hoppmann, Nicola, Heinig, Nora, Distler, Ute, Kim, Ella, Lennerz, Volker, Krauß, Yvonne, Schumann, Ulrike, Giese, Alf, Tenzer, Stefan, Bitar, Lynn, Schmidt, Mirko H H

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How Soluble GARP Enhances TGF[beta] Activation von Fridrich, Sven, Hahn, Susanne A, Linzmaier, Marion, Felten, Matthias, Zwarg, Jenny, Lennerz, Volker, Tuettenberg, Andrea, Stöcker, Walter

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Short Peptide Vaccine Induces CD4+ T Helper Cells in Patients with Different Solid Cancers von Gross, Stefanie, Lennerz, Volker, Gallerani, Elisa, Mach, Nicolas, Böhm, Steffen, Hess, Dagmar, von Boehmer, Lotta, Knuth, Alexander, Ochsenbein, Adrian, Gnad-Vogt, Ulrike, Forssmann, Ulf, Woelfel, Thomas, Kaempgen, Eckhart

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Allorestricted T lymphocytes with a high avidity T‐cell receptor towards NY‐ESO‐1 have potent anti‐tumor activity von Krönig, Holger, Hofer, Kathrin, Conrad, Heinke, Guilaume, Philippe, Müller, Julia, Schiemann, Matthias, Lennerz, Volker, Cosma, Antonio, Peschel, Christian, Busch, Dirk H., Romero, Pedro, Bernhard, Helga

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A key role of GARP in the immune suppressive tumor microenvironment von Hahn, Susanne A, Neuhoff, Annemarie, Landsberg, Jenny, Schupp, Jonathan, Eberts, Daniela, Leukel, Petra, Bros, Matthias, Weilbaecher, Martin, Schuppan, Detlef, Grabbe, Stephan, Tueting, Thomas, Lennerz, Volker, Sommer, Clemens, Jonuleit, Helmut, Tuettenberg, Andrea

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Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation von Beckhove, Philipp, Warta, Rolf, Lemke, Britt, Stoycheva, Diana, Momburg, Frank, Schnölzer, Martina, Warnken, Uwe, Schmitz-Winnenthal, Hubertus, Ahmadi, Rezvan, Dyckhoff, Gerhard, Bucur, Mariana, Jünger, Simone, Schueler, Thomas, Lennerz, Volker, Woelfel, Thomas, Unterberg, Andreas, Herold-Mende, Christel

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Abstract 5516: Therapeutic vaccination with the survivin-derived multi-epitope vaccine EMD640744 in patients with advanced solid tumors von Lennerz, Volker, Gross, Stefanie, Gallerani, Elisa, Sessa, Cristiana, Mach, Nicolas, Boehm, Steffen, Hess, Dagmar, von Boehmer, Lotta, Knuth, Alexander, Ochsenbein, Adrian, Gnad-Vogt, Ulrike, Zieschang, Juergen, Forssmann, Ulf, Wölfel, Thomas, Kaempgen, Eckhart

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