The Generation, Detection, and Effects of Reactive Drug Metabolites von Stachulski, Andrew V., Baillie, Thomas A., Kevin Park, B., Scott Obach, R., Dalvie, Deepak K., Williams, Dominic P., Srivastava, Abhishek, Regan, Sophie L., Antoine, Daniel J., Goldring, Christopher E. P., Chia, Alvin J. L., Kitteringham, Neil R., Randle, Laura E., Callan, Hayley, Castrejon, J. Luis, Farrell, John, Naisbitt, Dean J., Lennard, Martin S.

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CYP2D6 is Primarily Responsible for the Metabolism of Clomiphene von Ghobadi, Cyrus, Gregory, Anne, Kim Crewe, H., Rostami-Hodjegan, Amin, Lennard, Martin S.

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PRN prescribing in psychiatric inpatients – potential for pharmacokinetic drug interactions von Davies, Simon J. C., Lennard, Martin S., Ghahramani, Parviz, Pratt, Peter, Robertson, Andrea, Potokar, John

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Evaluation of the relationship between plasma concentrations of en- and zuclomiphene and induction of ovulation in anovulatory women being treated with clomiphene citrate von Ghobadi, Cyrus, M.B.Ch.B, Amer, Saad, M.D, Lashen, Hany, M.D, Lennard, Martin S., Ph.D, Ledger, William L., D.Phil, Rostami-Hodjegan, Amin, Ph.D

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Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: A predictive model and nomograms to aid clozapine dose adjustment and to... von ROSTAMI-HODJEGAN, Amin, AMIN, Ajmal M, SPENCER, Edgar P, LENNARD, Martin S, TUCKER, Geoffrey T, FLANAGAN, Robert J

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Contribution of the activities of CYP3A, CYP2D6, CYP1A2 and other potential covariates to the disposition of methadone in patients undergoing methadone maintenance treatment von Shiran, Mohammad‐Reza, Lennard, Martin S., Iqbal, Mohammad‐Zafar, Lagundoye, Oldwale, Seivewright, Nicholas, Tucker, Geoffrey T., Rostami‐Hodjegan, Amin

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Single-Dose Pharmacokinetic Study of Clomiphene Citrate Isomers in Anovular Patients With Polycystic Ovary Disease von Ghobadi, Cyrus, Mirhosseini, Nahid, Shiran, Mohammad Reza, Moghadamnia, Ali, Lennard, Martin S., Ledger, William L., Rostami-Hodjegan, Amin

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Pharmacokinetic-Pharmacodynamic Modeling of Mood and Withdrawal Symptoms in Relation to Plasma Concentrations of Methadone in Patients Undergoing Methadone Maintenance Treatment von SHIRAN, Mohammad-Reza, LENNARD, Martin S, IQBAL, Mohammad-Zafar, LAGUNDOYE, Olawale, SEIVEWRIGHT, Nicholas, TUCKER, Geoffrey T, ROSTAMI-HODJEGAN, Amin

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Incorporating In Vitro Information on Drug Metabolism Into Clinical Trial Simulations to Assess the Effect of CYP2D6 Polymorphism on Pharmacokinetics and Pharmacodynamics: Dextrome... von Dickinson, Gemma L., Rezaee, Saeed, Proctor, Nicholas J., Lennard, Martin S., Tucker, Geoffrey T., Rostami-Hodjegan, Amin

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The impact of experimental design on assessing mechanism-based inactivation of CYP2D6 by MDMA (Ecstasy) von Van, Linh M., Heydari, Amir, Yang, Jiansong, Hargreaves, Judith, Rowland-Yeo, Karen, Lennard, Martin S., Tucker, Geoffrey T., Rostami-Hodjegan, Amin

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Metabolism of ethylbenzene by human liver microsomes and recombinant human cytochrome P450s (CYP) von Sams, Craig, Loizou, George D, Cocker, John, Lennard, Martin S

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Influence of phenylalanine-481 substitutions on the catalytic activity of cytochrome P450 2D6 von Hayhurst, G P, Harlow, J, Chowdry, J, Gross, E, Hilton, E, Lennard, M S, Tucker, G T, Ellis, S W

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Oxidation Phenotype — A Major Determinant of Metoprolol Metabolism and Response von Lennard, Martin S, Silas, Joseph H, Freestone, Stephen, Ramsay, Lawrence E, Tucker, Geoffrey T, Woods, Hubert F

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Editors’ Report 2005 von Aronson, Jeffrey K., Lennard, Martin S., Ritter, James M., Baber, Nigel S., Begg, Evan J., Lewis, Lionel D.

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Today's science, tomorrow's medicines von Aronson, Jeffrey K., Lennard, Martin S., Ritter, James M., Baber, Nigel S., Begg, Evan J., Lewis, Lionel D.

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Editors’ Report 2004 von Aronson, Jeffrey K., Lennard, Martin S., Ritter, Janes M., Begg, Evan J., Baber, Nigel S.

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Does previous response to clomifene citrate influence the selection of gonadotropin dosage given in subsequent superovulation treatment cycles? von Nguyen, Tien Huu, Lennard, Martin S, Ghobadi, Cyrus, Rostami-Hodjegan, Amin, Ledger, William L

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Influence of amino acid residue 374 of cytochrome P-450 2D6 (CYP2D6) on the regio- and enantio-selective metabolism of metoprolol von Ellis, S W, Rowland, K, Ackland, M J, Rekka, E, Simula, A P, Lennard, M S, Wolf, C R, Tucker, G T

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The British Journal of Clinical Pharmacology Editors’ Report for 2003 von Aronson, Jeffrey K., Lennard, Martin S., Ritter, James M., Baber, Nigel S., Begg, Evan J.

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Drug Metabolism: The Body's Defense against Chemical Attack von Lennard, Martin S, Stachulski, Andrew V

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