Effects of Different Container Types on (1→3)-β-D-glucan Recovery von Burgmaier, Luisa, Illes, Bernhard, Leiss, Michael, Avci-Adali, Meltem, Reich, Johannes

Volltext

Rapid characterization of biotherapeutic proteins by size-exclusion chromatography coupled to native mass spectrometry von Haberger, Markus, Leiss, Michael, Heidenreich, Anna-Katharina, Pester, Oxana, Hafenmair, Georg, Hook, Michaela, Bonnington, Lea, Wegele, Harald, Haindl, Markus, Reusch, Dietmar, Bulau, Patrick

Volltext

Fast HPLC-based affinity method to determine capsid titer and full/empty ratio of adeno-associated viral vectors von Heckel, Jakob, Martinez, Andres, Elger, Carsten, Haindl, Markus, Leiss, Michael, Ruppert, Raphael, Williams, Chris, Hubbuch, Jürgen, Graf, Tobias

Volltext

Detailed Analytical Characterization of a Bispecific IgG1 CrossMab Antibody of the Knob-into-Hole Format Applying Various Stress Conditions Revealed Pronounced Stability von Grunert, Ingrid, Heinrich, Katrin, Ernst, Juliane, Hingar, Michael, Briguet, Alexandre, Leiss, Michael, Wuhrer, Manfred, Reusch, Dietmar, Bulau, Patrick

Volltext

Formation and activation of fibroblast spheroids depend on fibronectin–integrin interaction von Salmenperä, Pertteli, Kankuri, Esko, Bizik, Jozef, Sirén, Vappu, Virtanen, Ismo, Takahashi, Seiichiro, Leiss, Michael, Fässler, Reinhard, Vaheri, Antti

Volltext

Recent advances in LC–MS based characterization of protein-based bio-therapeutics – mastering analytical challenges posed by the increasing format complexity von Graf, Tobias, Heinrich, Katrin, Grunert, Ingrid, Wegele, Harald, Haberger, Markus, Bulau, Patrick, Leiss, Michael

Volltext

From proof of concept to the routine use of an automated and robust multi-dimensional liquid chromatography mass spectrometry workflow applied for the charge variant characterizati... von Goyon, Alexandre, Dai, Lu, Chen, Tao, Wei, Bingchuan, Yang, Feng, Andersen, Nisana, Kopf, Robert, Leiss, Michael, Mølhøj, Michael, Guillarme, Davy, Stella, Cinzia

Volltext

Controlled polysorbate 20 hydrolysis – A new approach to assess the impact of polysorbate 20 degradation on biopharmaceutical product quality in shortened time von Graf, Tobias, Abstiens, Kathrin, Wedekind, Frank, Elger, Carsten, Haindl, Markus, Wurth, Christine, Leiss, Michael

Volltext

The role of integrin binding sites in fibronectin matrix assembly in vivo von Leiss, Michael, Beckmann, Karsten, Girós, Amparo, Costell, Mercedes, Fässler, Reinhard

Volltext

Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation von Graf, Tobias, Tomlinson, Anthony, Yuk, Inn H., Kufer, Regina, Spensberger, Bernhard, Falkenstein, Roberto, Shen, Amy, Li, Hong, Duan, Dana, Liu, Wenqiang, Wohlrab, Stefanie, Edelmann, Franziska, Leiss, Michael

Volltext

Fast analysis of antibody-derived therapeutics by automated multidimensional liquid chromatography – Mass spectrometry von Pot, Sanne, Gstöttner, Christoph, Heinrich, Katrin, Hoelterhoff, Sina, Grunert, Ingrid, Leiss, Michael, Bathke, Anja, Domínguez-Vega, Elena

Volltext

Industry Perspective on the use and Characterization of Polysorbates for Biopharmaceutical Products Part 1: Survey Report on Current State and Common Practices for Handling and Con... von Wuchner, Klaus, Yi, Linda, Chery, Cyrille, Nikels, Felix, Junge, Friederike, Crotts, George, Rinaldi, Gianluca, Starkey, Jason A., Bechtold-Peters, Karoline, Shuman, Melissa, Leiss, Michael, Jahn, Michael, Garidel, Patrick, de Ruiter, Rien, Richer, Sarah M, Cao, Shawn, Peuker, Sebastian, Huille, Sylvain, Wang, Tingting, Le Brun, Virginie

Volltext

Inter-laboratory study to evaluate the performance of automated online characterization of antibody charge variants by multi-dimensional LC-MS/MS von Camperi, Julien, Grunert, Ingrid, Heinrich, Katrin, Winter, Martin, Özipek, Saban, Hoelterhoff, Sina, Weindl, Thomas, Mayr, Kilian, Bulau, Patrick, Meier, Monika, Mølhøj, Michael, Leiss, Michael, Guillarme, Davy, Bathke, Anja, Stella, Cinzia

Volltext

Industry Perspective on the Use and Characterization of Polysorbates for Biopharmaceutical Products Part 2: Survey Report on Control Strategy Preparing for the Future von Wuchner, Klaus, Yi, Linda, Chery, Cyrille, Nikels, Felix, Junge, Friederike, Crotts, George, Rinaldi, Gianluca, Starkey, Jason A, Bechtold-Peters, Karoline, Shuman, Melissa, Leiss, Michael, Jahn, Michael, Garidel, Patrick, de Ruiter, Rien, Richer, Sarah M, Cao, Shawn, Peuker, Sebastian, Huille, Sylvain, Wang, Tingting, Brun, Virginie Le

Volltext

A fast and sensitive high-throughput assay to assess polysorbate-degrading hydrolytic activity in biopharmaceuticals von Gupta, Sanjay K., Graf, Tobias, Edelmann, Franziska T., Seelmann, Helen, Reintinger, Markus, Hillringhaus, Lars, Bergmann, Frank, Wiedmann, Michael, Falkenstein, Roberto, Wegele, Harald, Yuk, Inn H., Leiss, Michael

Volltext

Expediting online liquid chromatography for real-time monitoring of product attributes to advance process analytical technology in downstream processing of biopharmaceuticals von Graf, Tobias, Naumann, Lukas, Bonnington, Lea, Heckel, Jakob, Spensberger, Bernhard, Klein, Sascha, Brey, Christoph, Nachtigall, Ronnie, Mroz, Maximilian, Hogg, Thomas Vagn, McHardy, Christopher, Martinez, Andrés, Braaz, Reinhard, Leiss, Michael

Volltext

RGD motif in fibronectin is essential for development but dispensable for fibril assembly von Takahashi, Seiichiro, Leiss, Michael, Moser, Markus, Ohashi, Tomoo, Kitao, Tomoe, Heckmann, Dominik, Pfeifer, Alexander, Kessler, Horst, Takagi, Junichi, Erickson, Harold P, Fässler, Reinhard

Volltext

Getting CHO host cell protein analysis up to speed von Leiss, Michael, Meier, Monika, Pester, Oxana, Aschner, Marion, Wedekind, Frank, Wiedmann, Michael, Wegele, Harald

Volltext

INDUCED CROSSTALK CIRCUIT FOR IMPROVED SENSOR LINEARITY von PARMLEY, Steven M, LEISS, Michael, POSEY, Douglas J, FLANAGAN, Kevin R

Volltext bestellen

METHOD FOR PRODUCING PROTEIN COMPOSITIONS von LEISS, Michael, FALKENSTEIN, Roberto, REMPT, Martin, EDELMANN, Franziska, WEDEKIND, Frank, GRAF, Tobias

Volltext bestellen