Metabolomic profiling of amines in sepsis predicts changes in NOS canonical pathways von Tesfai, Abel, MacCallum, Niall, Kirkby, Nicholas S, Gashaw, Hime, Gray, Nicola, Want, Elizabeth, Quinlan, Gregory J, Mumby, Sharon, Leiper, James M, Paul-Clark, Mark, Ahmetaj-Shala, Blerina, Mitchell, Jane A

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The synthesis and metabolism of asymmetric dimethylarginine (ADMA) von Leiper, James M., Vallance, Patrick

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Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension von MILLATT, Lesley J, WHITLEY, Guy Stj, LI, Dechun, LEIPER, James M, SIRAGY, Helmy M, CAREY, Robert M, JOHNS, Roger A

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Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA von Smith, Caroline L, Anthony, Shelagh, Hubank, Mike, Leiper, James M, Vallance, Patrick

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The role of ATM in response to metformin treatment and activation of AMPK von Woods, Angela, Leiper, James M, Carling, David

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Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity von D'Mello, Richard, Sand, Claire A., Pezet, Sophie, Leiper, James M., Gaurilcikaite, Egle, McMahon, Stephen B., Dickenson, Anthony H., Nandi, Manasi

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Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype von Smith, Caroline L., Birdsey, Graeme M., Anthony, Shelagh, Arrigoni, Francesca I., Leiper, James M., Vallance, Patrick

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ADMA/DDAH pathway is a critical regulator of endothelial cell motility von Wojciak-Stothard, Beata, Torondel, Belen, Tsang, Lillian Yen Fen, Fleming, Ingrid, Fisslthaler, Beate, Leiper, James M, Vallance, Patrick

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Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity von D'Mello, Richard, Sand, Claire A, Pezet, Sophie, Leiper, James M, Gaurilcikaite, Egle, McMahon, Stephen B, Dickenson, Anthony H, Nandi, Manasi

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Modulation of Rac1 activity by ADMA/DDAH regulates pulmonary endothelial barrier function von Wojciak-Stothard, Beata, Torondel, Belen, Zhao, Lan, Renné, Thomas, Leiper, James M

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Overexpression of GTP Cyclohydrolase 1 Feedback Regulatory Protein Is Protective in a Murine Model of Septic Shock von Starr, Anna, Sand, Claire A, Heikal, Lamia, Kelly, Peter D, Spina, Domenico, Crabtree, Mark, Channon, Keith M, Leiper, James M, Nandi, Manasi

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Response to Letters Regarding Article, “Unexpected Effect of Proton Pump Inhibitors: Elevation of the Cardiovascular Risk Factor Asymmetric Dimethylarginine” von Ghebremariam, Yohannes T, LePendu, Paea, Lee, Jerry C, Erlanson, Daniel A, Slaviero, Anna, Shah, Nigam H, Leiper, James M, Cooke, John P

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Active site mutant dimethylarginine dimethylaminohydrolase 1 expression confers an intermediate tumour phenotype in C6 gliomas von Boult, Jessica KR, Walker-Samuel, Simon, Jamin, Yann, Leiper, James M, Whitley, Guy St J, Robinson, Simon P

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Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia von ARRIGONI, Francesca I, VALLANCE, Patrick, HAWORTH, Sheila G, LEIPER, James M

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Circulating methylarginine levels and the decline in renal function in patients with chronic kidney disease are modulated by DDAH1 polymorphisms von Caplin, Ben, Nitsch, Dorothea, Gill, Herpreet, Hoefield, Richard, Blackwell, Scott, MacKenzie, Douglas, Cooper, Jackie A., Middleton, Rachel J., Talmud, Philippa J., Veitch, Peter, Norman, Jill, Wheeler, David C., Leiper, James M.

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all-trans-Retinoic Acid Increases Nitric Oxide Synthesis by Endothelial Cells: A Role for the Induction of Dimethylarginine Dimethylaminohydrolase von Achan, Vinod, Tran, Cam T.L, Arrigoni, Francesca, Whitley, Guy St.J, Leiper, James M, Vallance, Patrick

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Chromosomal Localization, Gene Structure, and Expression Pattern of DDAH1: Comparison with DDAH2 and Implications for Evolutionary Origins von Tran, Cam T.L., Fox, Margaret F., Vallance, Patrick, Leiper, James M.

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Selective Substrate-Based Inhibitors of Mammalian Dimethylarginine Dimethylaminohydrolase von Rossiter, Sharon, Smith, Caroline L, Malaki, Mohammed, Nandi, Manasi, Gill, Herpreet, Leiper, James M, Vallance, Patrick, Selwood, David L

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Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis von Hartzoulakis, Basil, Rossiter, Sharon, Gill, Herpreet, O’Hara, Bernard, Steinke, Emily, Gane, Paul J., Hurtado-Guerrero, Ramon, Leiper, James M., Vallance, Patrick, Rust, Judith Murray, Selwood, David L.

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Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction von Gray, Gillian A., Patrizio, Mark, Sherry, Lorcan, Miller, Alyson A., Malaki, Mohammed, Wallace, Alison F., Leiper, James M., Vallance, Patrick

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