Predictive Potential of Acido-Basic Properties, Solubility and Food on Bioequivalence Study Outcome: Analysis of 128 Studies von Krajcar, Dejan, Jereb, Rebeka, Legen, Igor, Opara, Jerneja, Grabnar, Iztok

Volltext

Biopharmaceutical classification of desloratadine - not all drugs are classified the easy way von Berginc, Katja, Sibinovska, Nadica, Žakelj, Simon, Trontelj, Jurij, Legen, Igor

Volltext

Determining the Polymer Threshold Amount for Achieving Robust Drug Release from HPMC and HPC Matrix Tablets Containing a High-Dose BCS Class I Model Drug: In Vitro and In Vivo Stud... von Klančar, Uroš, Baumgartner, Saša, Legen, Igor, Smrdel, Polona, Kampuš, Nataša Jeraj, Krajcar, Dejan, Markun, Boštjan, Kočevar, Klemen

Volltext

Physiologically based absorption modeling to predict bioequivalence of controlled release and immediate release oral products von Mitra, Amitava, Petek, Bostjan, Bajc, Aleksander, Velagapudi, Raja, Legen, Igor

Volltext

Factors Affecting the Microclimate pH of the Rat Jejunum in Ringer Bicarbonate Buffer von Legen, Igor, Kristl, Albin

Volltext

Predictive Potential of BCS and Pharmacokinetic Parameters on Study Outcome: Analysis of 198 In Vivo Bioequivalence Studies von Krajcar, Dejan, Grabnar, Iztok, Jereb, Rebeka, Legen, Igor, Opara, Jerneja

Volltext

D-glucose triggers multidrug resistance-associated protein (MRP)-mediated secretion of fluorescein across rat jejunum in vitro von Legen, Igor, Kristl, Albin

Volltext

Neuro-fuzzy Models as an IVIVR Tool and Their Applicability in Generic Drug Development von Opara, Jerneja, Legen, Igor

Volltext

In vitro–In vivo Relationship and Bioequivalence Prediction for Modified-Release Capsules Based on a PBPK Absorption Model von Jereb, Rebeka, Opara, Jerneja, Legen, Igor, Petek, Boštjan, Grabnar-Peklar, Darja

Volltext

The biorelevant simulation of gastric emptying and its impact on model drug dissolution and absorption kinetics von Vrbanac, Helena, Trontelj, Jurij, Berglez, Sandra, Petek, Boštjan, Opara, Jerneja, Jereb, Rebeka, Krajcar, Dejan, Legen, Igor

Volltext

Mechanistic study of model drug release from HPMC matrices in fed gastric media von Vrbanac, Helena, Trontelj, Jurij, Kalčič, Špela, Legen, Igor

Volltext

The influence of buffer composition on tissue integrity during permeability experiments “in vitro” von Žakelj, Simon, Legen, Igor, Veber, Marjan, Kristl, Albin

Volltext

PBPK Absorption Modeling of Food Effect and Bioequivalence in Fed State for Two Formulations with Crystalline and Amorphous Forms of BCS 2 Class Drug in Generic Drug Development von Rebeka, Jereb, Jerneja, Opara, Igor, Legen, Boštjan, Petek, Aleksander, Bajc, Simon, Žakelj, Albin, Kristl

Volltext

Ketoprofen-induced intestinal permeability changes studied in side-by-side diffusion cells von Legen, Igor, Kristl, Albin

Volltext

Determining The Pressure-Generating Capacity of The Classical and Alternative In Vitro Dissolution Methods Using a Wireless Motility Capsule von Hribar, Melita, Jakasanovski, Ognen, Trontelj, Jurij, Grabnar, Iztok, Legen, Igor

Volltext

Simulated migrating motor complex and its impact on the release properties of hydrophilic matrix systems von Vrbanac, Helena, Trontelj, Jurij, Berglez, Sandra, Kreft, Klemen, Krajcar, Dejan, Legen, Igor

Volltext

Design of an Innovative Advanced Gastric Simulator von Hribar, Melita, Trontelj, Jurij, Berglez, Sandra, Bevc, Alenka, Kuscer, Lovro, Diaci, Janez, Legen, Igor

Volltext

A Novel Intestine Model Apparatus for Drug Dissolution Capable of Simulating the Peristaltic Action von Hribar, Melita, Trontelj, Jurij, Klančar, Uroš, Markun, Boštjan, Čeligoj Dujc, Tanja, Legen, Igor

Volltext

Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Levetiracetam von Petruševska, Marija, Berglez, Sandra, Krisch, Igor, Legen, Igor, Megušar, Klara, Peternel, Luka, Abrahamsson, Bertil, Cristofoletti, Rodrigo, Groot, D.W., Kopp, Sabine, Langguth, Peter, Mehta, Mehul, Polli, James E., Shah, Vinod P., Dressman, Jennifer

Volltext

A Novel Beads-Based Dissolution Method for the In Vitro Evaluation of Extended Release HPMC Matrix Tablets and the Correlation with the In Vivo Data von Klančar, Uroš, Markun, Boštjan, Baumgartner, Saša, Legen, Igor

Volltext