Reserving the Right to Change the Intestinal Stem Cell Model von Leedham, Simon J.

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Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche von Davis, Hayley, Irshad, Shazia, Bansal, Mukesh, Rafferty, Hannah, Boitsova, Tatjana, Bardella, Chiara, Jaeger, Emma, Lewis, Annabelle, Freeman-Mills, Luke, Giner, Francesc C, Rodenas-Cuadrado, Pedro, Mallappa, Sreelakshmi, Clark, Susan, Thomas, Huw, Jeffery, Rosemary, Poulsom, Richard, Rodriguez-Justo, Manuel, Novelli, Marco, Chetty, Runjan, Silver, Andrew, Sansom, Owen J, Greten, Florian R, Wang, Lai Mun, East, James E, Tomlinson, Ian, Leedham, Simon J

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Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis von Lannagan, Tamsin R M, Lee, Young K, Wang, Tongtong, Roper, Jatin, Bettington, Mark L, Fennell, Lochlan, Vrbanac, Laura, Jonavicius, Lisa, Somashekar, Roshini, Gieniec, Krystyna, Yang, Miao, Ng, Jia Q, Suzuki, Nobumi, Ichinose, Mari, Wright, Josephine A, Kobayashi, Hiroki, Putoczki, Tracey L, Hayakawa, Yoku, Leedham, Simon J, Abud, Helen E, Yilmaz, Ömer H, Marker, Julie, Klebe, Sonja, Wirapati, Pratyaksha, Mukherjee, Siddhartha, Tejpar, Sabine, Leggett, Barbara A, Whitehall, Vicki L J, Worthley, Daniel L, Woods, Susan L

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British Society of Gastroenterology position statement on serrated polyps in the colon and rectum von East, James E, Atkin, Wendy S, Bateman, Adrian C, Clark, Susan K, Dolwani, Sunil, Ket, Shara N, Leedham, Simon J, Phull, Perminder S, Rutter, Matt D, Shepherd, Neil A, Tomlinson, Ian, Rees, Colin J

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Gremlin 1 — small protein, big impact: the multiorgan consequences of disrupted BMP antagonism von Gooding, Sarah, Leedham, Simon J

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Advances in colon cancer research: in vitro and animal models von Lannagan, Tamsin RM, Jackstadt, Rene, Leedham, Simon J, Sansom, Owen J

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Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning von Sirinukunwattana, Korsuk, Domingo, Enric, Richman, Susan D, Redmond, Keara L, Blake, Andrew, Verrill, Clare, Leedham, Simon J, Chatzipli, Aikaterini, Hardy, Claire, Whalley, Celina M, Wu, Chieh-hsi, Beggs, Andrew D, McDermott, Ultan, Dunne, Philip D, Meade, Angela, Walker, Steven M, Murray, Graeme I, Samuel, Leslie, Seymour, Matthew, Tomlinson, Ian, Quirke, Phil, Maughan, Timothy, Rittscher, Jens, Koelzer, Viktor H

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Evolutionary history of human colitis-associated colorectal cancer von Baker, Ann-Marie, Cross, William, Curtius, Kit, Al Bakir, Ibrahim, Choi, Chang-Ho Ryan, Davis, Hayley Louise, Temko, Daniel, Biswas, Sujata, Martinez, Pierre, Williams, Marc J, Lindsay, James O, Feakins, Roger, Vega, Roser, Hayes, Stephen J, Tomlinson, Ian P M, McDonald, Stuart A C, Moorghen, Morgan, Silver, Andrew, East, James E, Wright, Nicholas A, Wang, Lai Mun, Rodriguez-Justo, Manuel, Jansen, Marnix, Hart, Ailsa L, Leedham, Simon J, Graham, Trevor A

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MAP(K)ing the Path to Stem Cell Quiescence and the Elusive Enteroendocrine Cell von Leedham, Simon J.

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Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer von Kleeman, Sam O, Leedham, Simon J

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Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration von Koppens, Martijn A.J., Davis, Hayley, Valbuena, Gabriel N., Mulholland, Eoghan J., Nasreddin, Nadia, Colombe, Mathilde, Antanaviciute, Agne, Biswas, Sujata, Friedrich, Matthias, Lee, Lennard, Wang, Lai Mun, Koelzer, Viktor H., East, James E., Simmons, Alison, Winton, Douglas J., Leedham, Simon J.

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Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification von Kleeman, Sam O, Koelzer, Viktor H, Jones, Helen JS, Vazquez, Ester Gil, Davis, Hayley, East, James E, Arnold, Roland, Koppens, Martijn AJ, Blake, Andrew, Domingo, Enric, Cunningham, Chris, Beggs, Andrew D, Pestinger, Valerie, Loughrey, Maurice B, Wang, Lai-Mun, Lannagan, Tamsin RM, Woods, Susan L, Worthley, Daniel, Tomlinson, Ian, Dunne, Philip D, Maughan, Timothy, Leedham, Simon J

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Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer von Hashimoto, Taiki, Takayanagi, Daisuke, Yonemaru, Junpei, Naka, Tomoaki, Nagashima, Kengo, Yatabe, Yasushi, Shida, Dai, Hamamoto, Ryuji, Kleeman, Sam O., Leedham, Simon J., Maughan, Timothy, Takashima, Atsuo, Shiraishi, Kouya, Sekine, Shigeki

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Morphogen regulation of stem cell plasticity in intestinal regeneration and carcinogenesis von Eggington, Holly R., Mulholland, Eoghan J., Leedham, Simon J.

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Wnt disruption in colorectal polyps - the traditional serrated adenoma enters the fray von Leedham, Simon J, Chetty, Runjan

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Molecular mechanism of BMP signal control by Twisted gastrulation von Malinauskas, Tomas, Moore, Gareth, Rudolf, Amalie F., Eggington, Holly, Belnoue-Davis, Hayley L., El Omari, Kamel, Griffiths, Samuel C., Woolley, Rachel E., Duman, Ramona, Wagner, Armin, Leedham, Simon J., Baldock, Clair, Ashe, Hilary L., Siebold, Christian

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Microenvironmental control of stem cell fate in intestinal homeostasis and disease von Biswas, Sujata, Davis, Hayley, Irshad, Shazia, Sandberg, Tessa, Worthley, Daniel, Leedham, Simon

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Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia von Vasquez, Ester Gil, Nasreddin, Nadia, Valbuena, Gabriel N., Mulholland, Eoghan J., Belnoue-Davis, Hayley L., Eggington, Holly R., Schenck, Ryan O., Wouters, Valérie M., Wirapati, Pratyaksha, Gilroy, Kathryn, Lannagan, Tamsin R.M., Flanagan, Dustin J., Najumudeen, Arafath K., Omwenga, Sulochana, McCorry, Amy M.B., Easton, Alistair, Koelzer, Viktor H., East, James E., Morton, Dion, Trusolino, Livio, Maughan, Timothy, Campbell, Andrew D., Loughrey, Maurice B., Dunne, Philip D., Tsantoulis, Petros, Huels, David J., Tejpar, Sabine, Sansom, Owen J., Leedham, Simon J.

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The safety of autologous fat transfer in breast cancer: Lessons from stem cell biology von Pearl, Robert A, Leedham, Simon J, Pacifico, Marc D

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Measuring stem cell dynamics in the human colon - where there's a wiggle, there's a way von Leedham, Simon J

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