SYSTEMS AND METHODS FOR COMPOSABLE ANALYTICS von LOCKE RONALD TAYLOR, NAM KEVIN KYUNG, LAAD RAJENDRA F, LEE MICAH THOMAS, FIEDLER LARS HENRY, GRIFFIN HEATHER LYNN, DASEY TIMOTHY

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A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs von Wang, Zheng, Gearhart, Micah D., Lee, Yu-Wei, Kumar, Ishan, Ramazanov, Bulat, Zhang, Yan, Hernandez, Charles, Lu, Alice Y., Neuenkirchen, Nils, Deng, Jingjing, Jin, Jiaqi, Kluger, Yuval, Neubert, Thomas A., Bardwell, Vivian J., Ivanova, Natalia B.

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Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients With Pneumonia: A Prospective Observational Study von Bergin, Stephen P, Chemaly, Roy F, Dadwal, Sanjeet S, Hill, Joshua A, Lee, Yeon Joo, Haidar, Ghady, Luk, Alfred, Drelick, Alexander, Chin-Hong, Peter V, Benamu, Esther, Khawaja, Fareed, Nanayakkara, Deepa, Papanicolaou, Genovefa A, Small, Catherine Butkus, Fung, Monica, Barron, Michelle A, Davis, Thomas, McClain, Micah T, Maziarz, Eileen K, Madut, Deng B, Bedoya, Armando D, Gilstrap, Daniel L, Todd, Jamie L, Barkauskas, Christina E, Bigelow, Robert, Leimberger, Jeffrey D, Tsalik, Ephraim L, Wolf, Olivia, Mughar, Mona, Hollemon, Desiree, Duttagupta, Radha, Lupu, Daniel S, Bercovici, Sivan, Perkins, Bradley A, Blauwkamp, Timothy A, Fowler, Vance G, Holland, Thomas L

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Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria von Bell, Andrew, Severi, Emmanuele, Lee, Micah, Monaco, Serena, Latousakis, Dimitrios, Angulo, Jesus, Thomas, Gavin H., Naismith, James H., Juge, Nathalie

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Gut microbiota regulates cardiac ischemic tolerance and aortic stiffness in obesity von Battson, Micah L, Lee, Dustin M, Li Puma, Lance C, Ecton, Kayl E, Thomas, Keely N, Febvre, Hallie P, Chicco, Adam J, Weir, Tiffany L, Gentile, Christopher L

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Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 von Swadling, Leo, Diniz, Mariana O., Schmidt, Nathalie M., Amin, Oliver E., Chandran, Aneesh, Shaw, Emily, Pade, Corinna, Gibbons, Joseph M., Le Bert, Nina, Tan, Anthony T., Jeffery-Smith, Anna, Tan, Cedric C. S., Tham, Christine Y. L., Kucykowicz, Stephanie, Aidoo-Micah, Gloryanne, Rosenheim, Joshua, Davies, Jessica, Johnson, Marina, Jensen, Melanie P., Joy, George, McCoy, Laura E., Valdes, Ana M., Chain, Benjamin M., Goldblatt, David, Altmann, Daniel M., Boyton, Rosemary J., Manisty, Charlotte, Treibel, Thomas A., Moon, James C., van Dorp, Lucy, Balloux, Francois, McKnight, Áine, Noursadeghi, Mahdad, Bertoletti, Antonio, Maini, Mala K.

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Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders von Wang, Tianyun, Hoekzema, Kendra, Vecchio, Davide, Wu, Huidan, Sulovari, Arvis, Coe, Bradley P., Gillentine, Madelyn A., Wilfert, Amy B., Perez-Jurado, Luis A., Kvarnung, Malin, Sleyp, Yoeri, Earl, Rachel K., Rosenfeld, Jill A., Geisheker, Madeleine R., Han, Lin, Du, Bing, Barnett, Chris, Thompson, Elizabeth, Shaw, Marie, Carroll, Renee, Friend, Kathryn, Catford, Rachael, Palmer, Elizabeth E., Zou, Xiaobing, Ou, Jianjun, Li, Honghui, Guo, Hui, Gerdts, Jennifer, Avola, Emanuela, Calabrese, Giuseppe, Elia, Maurizio, Greco, Donatella, Lindstrand, Anna, Nordgren, Ann, Anderlid, Britt-Marie, Vandeweyer, Geert, Van Dijck, Anke, Van der Aa, Nathalie, McKenna, Brooke, Hancarova, Miroslava, Bendova, Sarka, Havlovicova, Marketa, Malerba, Giovanni, Bernardina, Bernardo Dalla, Muglia, Pierandrea, van Haeringen, Arie, Hoffer, Mariette J. V., Franke, Barbara, Cappuccio, Gerarda, Delatycki, Martin, Lockhart, Paul J., Manning, Melanie A., Liu, Pengfei, Scheffer, Ingrid E., Brunetti-Pierri, Nicola, Rommelse, Nanda, Amaral, David G., Santen, Gijs W. E., Trabetti, Elisabetta, Sedláček, Zdeněk, Michaelson, Jacob J., Pierce, Karen, Courchesne, Eric, Kooy, R. Frank, Nordenskjöld, Magnus, Romano, Corrado, Peeters, Hilde, Bernier, Raphael A., Gecz, Jozef, Xia, Kun, Eichler, Evan E.

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Microbial Metabolite Indole-3-Propionic Acid Supplementation Does Not Protect Mice from the Cardiometabolic Consequences of a Western Diet von Lee, Dustin M, Ecton, Kayl E, Trikha, S Raj J, Wrigley, Scott D, Thomas, Keely N, Battson, Micah L, Wei, Yuren, Johnson, Sarah A, Weir, Tiffany L, Gentile, Christopher L

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Transplantation of an obesity-associated human gut microbiota to mice induces vascular dysfunction and glucose intolerance von Trikha, S. Raj J., Lee, Dustin M., Ecton, Kayl E., Wrigley, Scott D., Vazquez, Allegra R., Litwin, Nicole S., Thomas, Keely N., Wei, Yuren, Battson, Micah L., Johnson, Sarah A., Kuhn, Kristine A., Colgan, Sean P., Gentile, Christopher L., Weir, Tiffany L.

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Increased Basal Ganglia Modulatory Effective Connectivity Observed in Resting-State fMRI in Individuals With Parkinson's Disease von Wapstra, Nicholas J, Ketola, Micah, Thompson, Shelby, Lee, Adel, Madhyastha, Tara, Grabowski, Thomas J, Stocco, Andrea

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Integrated gene analyses of de novo variants from 46,612 trios with autism and developmental disorders von Wang, Tianyun, Kim, Chang N., Bakken, Trygve E., Gillentine, Madelyn A., Henning, Barbara, Mao, Yafei, Gilissen, Christian, Nowakowski, Tomasz J., Eichler, Evan E.

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Rare deleterious mutations of HNRNP genes result in shared neurodevelopmental disorders von Gillentine, Madelyn A, Wang, Tianyun, Hoekzema, Kendra, Rosenfeld, Jill, Liu, Pengfei, Guo, Hui, Kim, Chang N, De Vries, Bert B A, Vissers, Lisenka E L M, Nordenskjold, Magnus, Kvarnung, Malin, Lindstrand, Anna, Nordgren, Ann, Gecz, Jozef, Iascone, Maria, Cereda, Anna, Scatigno, Agnese, Maitz, Silvia, Zanni, Ginevra, Bertini, Enrico, Zweier, Christiane, Schuhmann, Sarah, Wiesener, Antje, Pepper, Micah, Panjwani, Heena, Torti, Erin, Abid, Farida, Anselm, Irina, Srivastava, Siddharth, Atwal, Paldeep, Bacino, Carlos A, Bhat, Gifty, Cobian, Katherine, Bird, Lynne M, Friedman, Jennifer, Wright, Meredith S, Callewaert, Bert, Petit, Florence, Mathieu, Sophie, Afenjar, Alexandra, Christensen, Celenie K, White, Kerry M, Elpeleg, Orly, Berger, Itai, Espineli, Edward J, Fagerberg, Christina, Brasch-Andersen, Charlotte, Hansen, Lars Kjærsgaard, Feyma, Timothy, Hughes, Susan, Thiffault, Isabelle, Sullivan, Bonnie, Yan, Shuang, Keller, Kory, Keren, Boris, Mignot, Cyril, Kooy, Frank, Meuwissen, Marije, Basinger, Alice, Kukolich, Mary, Philips, Meredith, Ortega, Lucia, Drummond-Borg, Margaret, Lauridsen, Mathilde, Sorensen, Kristina, Lehman, Anna, Lopez-Rangel, Elena, Levy, Paul, Lessel, Davor, Lotze, Timothy, Madan-Khetarpal, Suneeta, Sebastian, Jessica, Vento, Jodie, Vats, Divya, Benman, L Manace, Mckee, Shane, Mirzaa, Ghayda M, Muss, Candace, Pappas, John, Peeters, Hilde, Romano, Corrado, Elia, Maurizio, Galesi, Ornella, Simon, Marleen E H, van Gassen, Koen L I, Simpson, Kara, Stratton, Robert, Syed, Sabeen, Thevenon, Julien, Palafoll, Irene Valenzuela, Vitobello, Antonio, Bournez, Marie, Faivre, Laurence, Xia, Kun, Earl, Rachel K, Nowakowski, Tomasz, Bernier, Raphael A, Eichler, Evan E

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Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease populat... von Astor, Brad C., Matsushita, Kunihiro, Gansevoort, Ron T., van der Velde, Marije, Woodward, Mark, Levey, Andrew S., Jong, Paul E. de, Coresh, Josef, the Chronic Kidney Disease Prognosis Consortium

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Identifying Candidates for Novel Customized Probiotics Targeting Obesity‐Related Vascular Dysfunction von Ecton, Kayl E., Lee, Dustin M., Trikha, S. Raj J., Wrigley, Scott, Battson, Micah L., Thomas, Keely N., Weir, Tiffany L., Gentile, Christopher L.

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Outbreak of Acute Respiratory Illness Associated With Human Adenovirus Type 4 at the United States Coast Guard Academy, 2019 von Chu, Victoria T, Simon, Esan, Lu, Xiaoyan, Rockwell, Patrick, Abedi, Glen R, Gardner, Christopher, Kujawski, Stephanie A, Schneider, Eileen, Gentile, Micah, Ramsey, Lee Ann, Liu, Robert, Jones, Sydney, Janik, Christopher, Siniscalchi, Alan, Landry, Marie L, Christopher, Jeffrey, Lindstrom, Stephen, Steiner, Shane, Thomas, Dana, Gerber, Susan I, Biggs, Holly M

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Endothelial Dysfunction is Transferable from Humans to Germ‐Free Mice via Fecal Microbiota Transplantation von Trikha, Raj, Lee, Dustin M., Ecton, Kayl E., Wrigley, Scott D., Vazquez, Allegra R., Litwin, Nicole S., Thomas, Keely N., Battson, Micah L., Johnson, Sarah A., Weir, Tiffany L., Gentile, Christopher L.

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Author Correction: Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders von Wang, Tianyun, Hoekzema, Kendra, Vecchio, Davide, Wu, Huidan, Sulovari, Arvis, Coe, Bradley P., Gillentine, Madelyn A., Wilfert, Amy B., Perez-Jurado, Luis A., Kvarnung, Malin, Sleyp, Yoeri, Earl, Rachel K., Rosenfeld, Jill A., Geisheker, Madeleine R., Han, Lin, Du, Bing, Barnett, Chris, Thompson, Elizabeth, Shaw, Marie, Carroll, Renee, Friend, Kathryn, Catford, Rachael, Palmer, Elizabeth E., Zou, Xiaobing, Ou, Jianjun, Li, Honghui, Guo, Hui, Gerdts, Jennifer, Avola, Emanuela, Calabrese, Giuseppe, Elia, Maurizio, Greco, Donatella, Lindstrand, Anna, Nordgren, Ann, Anderlid, Britt-Marie, Vandeweyer, Geert, Van Dijck, Anke, Van der Aa, Nathalie, McKenna, Brooke, Hancarova, Miroslava, Bendova, Sarka, Havlovicova, Marketa, Malerba, Giovanni, Bernardina, Bernardo Dalla, Muglia, Pierandrea, van Haeringen, Arie, Hoffer, Mariette J. V., Franke, Barbara, Cappuccio, Gerarda, Delatycki, Martin, Lockhart, Paul J., Manning, Melanie A., Liu, Pengfei, Scheffer, Ingrid E., Brunetti-Pierri, Nicola, Rommelse, Nanda, Amaral, David G., Santen, Gijs W. E., Trabetti, Elisabetta, Sedláček, Zdeněk, Michaelson, Jacob J., Pierce, Karen, Courchesne, Eric, Kooy, R. Frank, Nordenskjöld, Magnus, Romano, Corrado, Peeters, Hilde, Bernier, Raphael A., Gecz, Jozef, Xia, Kun, Eichler, Evan E.

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870. Plasma microbial cell-free DNA sequencing impacts antimicrobial management in immunocompromised patients with pneumonia von Madut, Deng B, Chemaly, Roy F, Dadwal, Sanjeet S, Hill, Joshua A, Lee, Yeon Joo, Haidar, Ghady, Luk, Alfred, Drelick, Alexander Christian, Chin-Hong, Peter V, Benamu, Esther, Khawaja, Fareed, Nanayakkara, Deepa D, Papanicolaou, Genovefa, Small, Catherine, Fung, Monica, Barron, Michelle, Davis, Thomas, McClain, Micah T, Maziarz, Eileen K, Bedoya, Armando, Gilstrap, Daniel, Todd, Jamie, Heldman, Madeleine R, Barkauskaus, Christina, Bigelow, Robert, Leimberger, Jeffrey, Tsalik, Ephraim, Wolf, Olivia, Mughar, Mona, Hollemon, Desiree, Duttagupta, Radha, Lupu, Daniel, Bercovici, Sivan, Perkins, Bradley A, Blauwkamp, Timothy A, Fowler, Vance G, Holland, Thomas L, Bergin, Stephen P

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Optimization of a Novel DEL Hit That Binds in the Cbl‑b SH2 Domain and Blocks Substrate Binding von Liang, Jun, Lambrecht, Michael J., Arenzana, Teresita L., Aubert-Nicol, Samuel, Bao, Linda, Broccatelli, Fabio, Cai, Jianping, Eidenschenk, Celine, Everett, Christine, Garner, Thomas, Gruber, Felix, Haghshenas, Pouyan, Huestis, Malcolm P., Hsu, Peter L., Kou, Ponien, Jakalian, Araz, Larouche-Gauthier, Robin, Leclerc, Jean-Philippe, Leung, Dennis H., Martin, Aaron, Murray, Jeremy, Prangley, Madeleine, Rutz, Sascha, Kakiuchi-Kiyota, Satoko, Satz, Alexander Lee, Skelton, Nicholas J., Steffek, Micah, Stoffler, Daniel, Sudhamsu, Jawahar, Tan, Sophia, Wang, Jian, Wang, Shouliang, Wang, Qiuyue, Wendorff, Timothy J., Wichert, Moreno, Yadav, Arun, Yu, Christine, Wang, Xiaojing

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544. PICKUP: Pneumonia in the Immunocompromised - Use of the Karius Test for Detection of Undiagnosed Pathogens von Bergin, Stephen P, Chemaly, Roy F, Duttagupta, Radha, Bigelow, Robert, Dadwal, Sanjeet S, Hill, Joshua A, Lee, Yeon Joo, Haidar, Ghady, Luk, Alfred, Drelick, Alexander Christian, Chin-Hong, Peter V, Benamu, Esther, Davis, Thomas, Wolf, Olivia, McClain, Micah T, Maziarz, Eileen K, Madut, Deng, Bedoya, Armando, Gilstrap, Daniel L, Todd, Jamie, Barkauskas, Christina, Puing, Alfredo, Spallone, Amy, McDowell, Brittany J, Shariff, Dayana, Salsgiver, Elizabeth, Nanayakkara, Deepa D, Khawaja, Fareed, Papanicolaou, Genovefa, Spagnoletti, Jack, English, Marico, Fung, Monica, Russel, Patrick, Ibrahimi, Sarah, Pandey, Shraddha, Adams, Suzanne, Liang, Wendy, Nemirovich-Danchenko, Elena, Mughar, Mona, Dalai, Sudeb, Cho, Yuen, Ahmed, Asim A, Hollemon, Desiree, Hong, David K, Vaughn, Marla Lay, Blauwkamp, Tim, Vucetic, Zivjena, Romano, Rina, Fowler, Vance G, Holland, Thomas L

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