Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species von Scotter, Emma L, Vance, Caroline, Nishimura, Agnes L, Lee, Youn-Bok, Chen, Han-Jou, Urwin, Hazel, Sardone, Valentina, Mitchell, Jacqueline C, Rogelj, Boris, Rubinsztein, David C, Shaw, Christopher E

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Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic von Lee, Youn-Bok, Chen, Han-Jou, Peres, João N., Gomez-Deza, Jorge, Attig, Jan, Štalekar, Maja, Troakes, Claire, Nishimura, Agnes L., Scotter, Emma L., Vance, Caroline, Adachi, Yoshitsugu, Sardone, Valentina, Miller, Jack W., Smith, Bradley N., Gallo, Jean-Marc, Ule, Jernej, Hirth, Frank, Rogelj, Boris, Houart, Corinne, Shaw, Christopher E.

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The increasing diversity of functions attributed to the SAFB family of RNA-/DNA-binding proteins von Norman, Michael, Rivers, Caroline, Lee, Youn-Bok, Idris, Jalilah, Uney, James

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Cytoplasmic TDP-43 is involved in cell fate during stress recovery von Lee, Youn-Bok, Scotter, Emma L, Lee, Do-Young, Troakes, Claire, Mitchell, Jacqueline, Rogelj, Boris, Gallo, Jean-Marc, Shaw, Christopher E

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MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex von Scott, Helen L., Tamagnini, Francesco, Narduzzo, Katherine E., Howarth, Joanna L., Lee, Youn-Bok, Wong, Liang-Fong, Brown, Malcolm W., Warburton, Elizabeth C., Bashir, Zafar I., Uney, James B.

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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity von Lee, Youn-Bok, Baskaran, Pranetha, Gomez-Deza, Jorge, Chen, Han-Jou, Nishimura, Agnes L, Smith, Bradley N, Troakes, Claire, Adachi, Yoshitsugu, Stepto, Alan, Petrucelli, Leonard, Gallo, Jean-Marc, Hirth, Frank, Rogelj, Boris, Guthrie, Sarah, Shaw, Christopher E

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Twist-1 regulates the miR-199a/214 cluster during development von Lee, Youn-Bok, Bantounas, Ioannis, Lee, Do-Young, Phylactou, Leonidas, Caldwell, Maeve A, Uney, James B

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RNA Misprocessing in C9orf72 -Linked Neurodegeneration von Barker, Holly V, Niblock, Michael, Lee, Youn-Bok, Shaw, Christopher E, Gallo, Jean-Marc

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Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells von Nishimura, Agnes L, Shum, Carole, Scotter, Emma L, Abdelgany, Amr, Sardone, Valentina, Wright, Jamie, Lee, Youn-Bok, Chen, Han-Jou, Bilican, Bilada, Carrasco, Monica, Maniatis, Tom, Chandran, Siddharthan, Rogelj, Boris, Gallo, Jean-Marc, Shaw, Christopher E

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Disease Mechanisms and Therapeutic Approaches in C9orf72 ALS-FTD von Mayl, Keith, Shaw, Christopher E, Lee, Youn-Bok

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Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95 von Jo, Jihoon, Son, Gi Hoon, Winters, Bryony L, Kim, Myung Jong, Whitcomb, Daniel J, Dickinson, Bryony A, Lee, Youn-Bok, Futai, Kensuke, Amici, Mascia, Sheng, Morgan, Collingridge, Graham L, Cho, Kwangwook

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iCLIP identifies novel roles for SAFB1 in regulating RNA processing and neuronal function von Rivers, Caroline, Idris, Jalilah, Scott, Helen, Rogers, Mark, Lee, Youn-Bok, Gaunt, Jessica, Phylactou, Leonidas, Curk, Tomaz, Campbell, Colin, Ule, Jernej, Norman, Michael, Uney, James B

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Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD von Niblock, Michael, Smith, Bradley N, Lee, Youn-Bok, Sardone, Valentina, Topp, Simon, Troakes, Claire, Al-Sarraj, Safa, Leblond, Claire S, Dion, Patrick A, Rouleau, Guy A, Shaw, Christopher E, Gallo, Jean-Marc

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A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration von Solomon, Daniel A, Stepto, Alan, Au, Wing Hei, Adachi, Yoshitsugu, Diaper, Danielle C, Hall, Rachel, Rekhi, Anjeet, Boudi, Adel, Tziortzouda, Paraskevi, Lee, Youn-Bok, Smith, Bradley, Bridi, Jessika C, Spinelli, Greta, Dearlove, Jonah, Humphrey, Dickon M, Gallo, Jean-Marc, Troakes, Claire, Fanto, Manolis, Soller, Matthias, Rogelj, Boris, Parsons, Richard B, Shaw, Christopher E, Hortobágyi, Tibor, Hirth, Frank

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Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA von Božič, Janja, Motaln, Helena, Janež, Anja Pucer, Markič, Lara, Tripathi, Priyanka, Yamoah, Alfred, Aronica, Eleonora, Lee, Youn-Bok, Heilig, Raphael, Fischer, Roman, Thompson, Andrew J, Goswami, Anand, Rogelj, Boris

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Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies von Bajc Česnik, Ana, Darovic, Simona, Prpar Mihevc, Sonja, Štalekar, Maja, Malnar, Mirjana, Motaln, Helena, Lee, Youn-Bok, Mazej, Julija, Pohleven, Jure, Grosch, Markus, Modic, Miha, Fonovič, Marko, Turk, Boris, Drukker, Micha, Shaw, Christopher E, Rogelj, Boris

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Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their... von Gomez-Deza, Jorge, Lee, Youn-Bok, Troakes, Claire, Nolan, Matthew, Al-Sarraj, Safa, Gallo, Jean-Marc, Shaw, Christopher E

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Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons von Shum, Carole, Hedges, Erin C., Allison, Joseph, Lee, Youn-bok, Arias, Natalia, Cocks, Graham, Chandran, Siddharthan, Ruepp, Marc-David, Shaw, Christopher E., Nishimura, Agnes L.

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Phosphorylation of C-terminal tyrosine residue 526 in FUS impairs its nuclear import von Darovic, Simona, Prpar Mihevc, Sonja, Župunski, Vera, Gunčar, Gregor, Štalekar, Maja, Lee, Youn-Bok, Shaw, Christopher E, Rogelj, Boris

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SAFB re-distribution marks steps of the apoptotic process von Lee, Youn-Bok, Colley, Shane, Norman, Michel, Biamonti, Giuseppe, Uney, James B.

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