Transcriptional Regulation and Its Misregulation in Disease von Lee, Tong Ihn, Young, Richard A.

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Pol II phosphorylation regulates a switch between transcriptional and splicing condensates von Guo, Yang Eric, Manteiga, John C., Henninger, Jonathan E., Sabari, Benjamin R., Dall’Agnese, Alessandra, Hannett, Nancy M., Spille, Jan-Hendrik, Afeyan, Lena K., Zamudio, Alicia V., Shrinivas, Krishna, Abraham, Brian J., Boija, Ann, Decker, Tim-Michael, Rimel, Jenna K., Fant, Charli B., Lee, Tong Ihn, Cisse, Ibrahim I., Sharp, Phillip A., Taatjes, Dylan J., Young, Richard A.

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Coactivator condensation at super-enhancers links phase separation and gene control von Sabari, Benjamin R, Dall'Agnese, Alessandra, Boija, Ann, Klein, Isaac A, Coffey, Eliot L, Shrinivas, Krishna, Abraham, Brian J, Hannett, Nancy M, Zamudio, Alicia V, Manteiga, John C, Li, Charles H, Guo, Yang E, Day, Daniel S, Schuijers, Jurian, Vasile, Eliza, Malik, Sohail, Hnisz, Denes, Lee, Tong Ihn, Cisse, Ibrahim I, Roeder, Robert G, Sharp, Phillip A, Chakraborty, Arup K, Young, Richard A

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Super-Enhancers in the Control of Cell Identity and Disease von Hnisz, Denes, Abraham, Brian J., Lee, Tong Ihn, Lau, Ashley, Saint-André, Violaine, Sigova, Alla A., Hoke, Heather A., Young, Richard A.

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Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes von Whyte, Warren A., Orlando, David A., Hnisz, Denes, Abraham, Brian J., Lin, Charles Y., Kagey, Michael H., Rahl, Peter B., Lee, Tong Ihn, Young, Richard A.

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Convergence of Developmental and Oncogenic Signaling Pathways at Transcriptional Super-Enhancers von Hnisz, Denes, Schuijers, Jurian, Lin, Charles Y., Weintraub, Abraham S., Abraham, Brian J., Lee, Tong Ihn, Bradner, James E., Young, Richard A.

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Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes von Dowen, Jill M., Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J., Zhang, Lyndon N., Weintraub, Abraham S., Schuijers, Jurian, Lee, Tong Ihn, Zhao, Keji, Young, Richard A.

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Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers von Lovén, Jakob, Hoke, Heather A., Lin, Charles Y., Lau, Ashley, Orlando, David A., Vakoc, Christopher R., Bradner, James E., Lee, Tong Ihn, Young, Richard A.

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3D Chromosome Regulatory Landscape of Human Pluripotent Cells von Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.

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Genome-wide Map of Nucleosome Acetylation and Methylation in Yeast von Pokholok, Dmitry K., Harbison, Christopher T., Levine, Stuart, Cole, Megan, Hannett, Nancy M., Lee, Tong Ihn, Bell, George W., Walker, Kimberly, Rolfe, P. Alex, Herbolsheimer, Elizabeth, Zeitlinger, Julia, Lewitter, Fran, Gifford, David K., Young, Richard A.

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Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells von Boyer, Laurie A., Lee, Tong Ihn, Cole, Megan F., Johnstone, Sarah E., Levine, Stuart S., Zucker, Jacob P., Guenther, Matthew G., Kumar, Roshan M., Murray, Heather L., Jenner, Richard G., Gifford, David K., Melton, Douglas A., Jaenisch, Rudolf, Young, Richard A.

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A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity von D’Alessio, Ana C., Fan, Zi Peng, Wert, Katherine J., Baranov, Petr, Cohen, Malkiel A., Saini, Janmeet S., Cohick, Evan, Charniga, Carol, Dadon, Daniel, Hannett, Nancy M., Young, Michael J., Temple, Sally, Jaenisch, Rudolf, Lee, Tong Ihn, Young, Richard A.

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Computational discovery of gene modules and regulatory networks von Gifford, David K, Bar-Joseph, Ziv, Gerber, Georg K, Lee, Tong Ihn, Rinaldi, Nicola J, Yoo, Jane Y, Robert, François, Gordon, D Benjamin, Fraenkel, Ernest, Jaakkola, Tommi S, Young, Richard A

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Transcriptional Amplification in Tumor Cells with Elevated c-Myc von Lin, Charles Y., Lovén, Jakob, Rahl, Peter B., Paranal, Ronald M., Burge, Christopher B., Bradner, James E., Lee, Tong Ihn, Young, Richard A.

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Activation of proto-oncogenes by disruption of chromosome neighborhoods von Hnisz, Denes, Weintraub, Abraham S., Day, Daniel S., Valton, Anne-Laure, Bak, Rasmus O., Li, Charles H., Goldmann, Johanna, Lajoie, Bryan R., Fan, Zi Peng, Sigova, Alla A., Reddy, Jessica, Borges-Rivera, Diego, Lee, Tong Ihn, Jaenisch, Rudolf, Porteus, Matthew H., Dekker, Job, Young, Richard A.

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MeCP2 links heterochromatin condensates and neurodevelopmental disease von Li, Charles H., Coffey, Eliot L., Dall’Agnese, Alessandra, Hannett, Nancy M., Tang, Xin, Henninger, Jonathan E., Platt, Jesse M., Oksuz, Ozgur, Zamudio, Alicia V., Afeyan, Lena K., Schuijers, Jurian, Liu, X. Shawn, Markoulaki, Styliani, Lungjangwa, Tenzin, LeRoy, Gary, Svoboda, Devon S., Wogram, Emile, Lee, Tong Ihn, Jaenisch, Rudolf, Young, Richard A.

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CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer von Wang, Yubao, Zhang, Tinghu, Kwiatkowski, Nicholas, Abraham, Brian J., Lee, Tong Ihn, Xie, Shaozhen, Yuzugullu, Haluk, Von, Thanh, Li, Heyuan, Lin, Ziao, Stover, Daniel G., Lim, Elgene, Wang, Zhigang C., Iglehart, J. Dirk, Young, Richard A., Gray, Nathanael S., Zhao, Jean J.

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Models of human core transcriptional regulatory circuitries von Saint-André, Violaine, Federation, Alexander J, Lin, Charles Y, Abraham, Brian J, Reddy, Jessica, Lee, Tong Ihn, Bradner, James E, Young, Richard A

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Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism von Schuijers, Jurian, Manteiga, John Colonnese, Weintraub, Abraham Selby, Day, Daniel Sindt, Zamudio, Alicia Viridiana, Hnisz, Denes, Lee, Tong Ihn, Young, Richard Allen

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Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas von Clark, Victoria E, Harmancı, Akdes Serin, Bai, Hanwen, Youngblood, Mark W, Lee, Tong Ihn, Baranoski, Jacob F, Ercan-Sencicek, A Gulhan, Abraham, Brian J, Weintraub, Abraham S, Hnisz, Denes, Simon, Matthias, Krischek, Boris, Erson-Omay, E Zeynep, Henegariu, Octavian, Carrión-Grant, Geneive, Mishra-Gorur, Ketu, Durán, Daniel, Goldmann, Johanna E, Schramm, Johannes, Goldbrunner, Roland, Piepmeier, Joseph M, Vortmeyer, Alexander O, Günel, Jennifer Moliterno, Bilgüvar, Kaya, Yasuno, Katsuhito, Young, Richard A, Günel, Murat

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