PRC2 is high maintenance von Yu, Jia-Ray, Lee, Chul-Hwan, Oksuz, Ozgur, Stafford, James M, Reinberg, Danny

Volltext

Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin von Lee, Chul-Hwan, Yu, Jia-Ray, Kumar, Sunil, Jin, Ying, LeRoy, Gary, Bhanu, Natarajan, Kaneko, Syuzo, Garcia, Benjamin A., Hamilton, Andrew D., Reinberg, Danny

Volltext

Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma von Lee, Chul-Hwan, Yu, Jia-Ray, Granat, Jeffrey, Saldaña-Meyer, Ricardo, Andrade, Joshua, LeRoy, Gary, Jin, Ying, Lund, Peder, Stafford, James M, Garcia, Benjamin A, Ueberheide, Beatrix, Reinberg, Danny

Volltext

Distinct Stimulatory Mechanisms Regulate the Catalytic Activity of Polycomb Repressive Complex 2 von Lee, Chul-Hwan, Holder, Marlene, Grau, Daniel, Saldaña-Meyer, Ricardo, Yu, Jia-Ray, Ganai, Rais Ahmad, Zhang, Jenny, Wang, Miao, LeRoy, Gary, Dobenecker, Marc-Werner, Reinberg, Danny, Armache, Karim-Jean

Volltext

H1 histones control the epigenetic landscape by local chromatin compaction von Willcockson, Michael A., Healton, Sean E., Weiss, Cary N., Bartholdy, Boris A., Botbol, Yair, Mishra, Laxmi N., Sidhwani, Dhruv S., Wilson, Tommy J., Pinto, Hugo B., Maron, Maxim I., Skalina, Karin A., Toro, Laura Norwood, Zhao, Jie, Lee, Chul-Hwan, Hou, Harry, Yusufova, Nevin, Meydan, Cem, Osunsade, Adewola, David, Yael, Cesarman, Ethel, Melnick, Ari M., Sidoli, Simone, Garcia, Benjamin A., Edelmann, Winfried, Macian, Fernando, Skoultchi, Arthur I.

Volltext

Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction von Grau, Daniel, Zhang, Yixiao, Lee, Chul-Hwan, Valencia-Sánchez, Marco, Zhang, Jenny, Wang, Miao, Holder, Marlene, Svetlov, Vladimir, Tan, Dongyan, Nudler, Evgeny, Reinberg, Danny, Walz, Thomas, Armache, Karim-Jean

Volltext

Nucleosome Contact Triggers Conformational Changes of Rpd3S Driving High-Affinity H3K36me Nucleosome Engagement von Ruan, Chun, Lee, Chul-Hwan, Cui, Haochen, Li, Sheng, Li, Bing

Volltext

Multivalent di-nucleosome recognition enables the Rpd3S histone deacetylase complex to tolerate decreased H3K36 methylation levels von Huh, Jae-Wan, Wu, Jun, Lee, Chul-Hwan, Yun, Miyong, Gilada, Daniel, Brautigam, Chad A, Li, Bing

Volltext

Capturing the Onset of PRC2-Mediated Repressive Domain Formation von Oksuz, Ozgur, Narendra, Varun, Lee, Chul-Hwan, Descostes, Nicolas, LeRoy, Gary, Raviram, Ramya, Blumenberg, Lili, Karch, Kelly, Rocha, Pedro P., Garcia, Benjamin A., Skok, Jane A., Reinberg, Danny

Volltext

Physical and functional interactions between nucleosomes and Rad27, a critical component of DNA processing during DNA metabolism von Kwon, Buki, Munashingha, Palinda Ruvan, Shin, Yong‐Keol, Lee, Chul‐Hwan, Li, Bing, Seo, Yeon‐Soo

Volltext

Techniques to Study Automethylation of Histone Methyltransferases and its Functional Impact von Popoca, Luis, Lee, Chul-Hwan

Volltext

Chromatin Remodelers Fine-Tune H3K36me-Directed Deacetylation of Neighbor Nucleosomes by Rpd3S von Lee, Chul-Hwan, Wu, Jun, Li, Bing

Volltext

The role of EZH1 and EZH2 in development and cancer von Lee, Soo Hyun, Li, Yingying, Kim, Hanbyeol, Eum, Seounghyun, Park, Kyumin, Lee, Chul-Hwan

Volltext

Epithelial−mesenchymal transition induced by tumor cell-intrinsic PD-L1 signaling predicts a poor response to immune checkpoint inhibitors in PD-L1-high lung cancer von Jeong, Hyein, Koh, Jaemoon, Kim, Sehui, Song, Seung Geun, Lee, Soo Hyun, Jeon, Youngjoo, Lee, Chul-Hwan, Keam, Bhumsuk, Lee, Se-Hoon, Chung, Doo Hyun, Jeon, Yoon Kyung

Volltext

Homodimeric PHD Domain-containing Rco1 Subunit Constitutes a Critical Interaction Hub within the Rpd3S Histone Deacetylase Complex von Ruan, Chun, Cui, Haochen, Lee, Chul-Hwan, Li, Sheng, Li, Bing

Volltext

The MPH1 Gene of Saccharomyces cerevisiae Functions in Okazaki Fragment Processing von Kang, Young-Hoon, Kang, Min-Jung, Kim, Jeong-Hoon, Lee, Chul-Hwan, Cho, Il-taeg, Hurwitz, Jerard, Seo, Yeon-Soo

Volltext

Analysis of subunit assembly and function of the Saccharomyces cerevisiae RNase H2 complex von Nguyen, Tuan Anh, Tak, Yon‐Soo, Lee, Chul‐Hwan, Kang, Young‐Hoon, Cho, Il‐Taeg, Seo, Yeon‐Soo

Volltext

Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma von Stafford, James M, Lee, Chul-Hwan, Voigt, Philipp, Descostes, Nicolas, Saldaña-Meyer, Ricardo, Yu, Jia-Ray, Leroy, Gary, Oksuz, Ozgur, Chapman, Jessica R, Suarez, Fernando, Modrek, Aram S, Bayin, N Sumru, Placantonakis, Dimitris G, Karajannis, Matthias A, Snuderl, Matija, Ueberheide, Beatrix, Reinberg, Danny

Volltext

LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells von LeRoy, Gary, Oksuz, Ozgur, Descostes, Nicolas, Aoi, Yuki, Ganai, Rais A, Kara, Havva Ortabozkoyun, Yu, Jia-Ray, Lee, Chul-Hwan, Stafford, James, Shilatifard, Ali, Reinberg, Danny

Volltext

GSK-3β Homolog Rim11 and the Histone Deacetylase Complex Ume6-Sin3-Rpd3 Are Involved in Replication Stress Response Caused by Defects in Dna2 von Demin, Annie Albert, Lee, Miju, Lee, Chul-Hwan, Seo, Yeon-Soo

Volltext