Peroxiredoxin 1 functions as a signal peroxidase to receive, transduce, and transmit peroxide signals in mammalian cells von Jarvis, Reagan M., Hughes, Stephanie M., Ledgerwood, Elizabeth C.

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The role of peroxiredoxin 1 in redox sensing and transducing von Ledgerwood, Elizabeth C., Marshall, James W.A., Weijman, Johannes F.

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Megakaryocytes from CYCS mutation‐associated thrombocytopenia release platelets by both proplatelet‐dependent and ‐independent processes von Ong, Lily, Morison, Ian M., Ledgerwood, Elizabeth C.

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Differentiation and cell density upregulate cytochrome c levels in megakaryoblastic cell lines: Implications for analysis of CYCS-associated thrombocytopenia von Ong, Lily, McDonald, Kirstin O, Ledgerwood, Elizabeth C

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Targeting the Apoptosome for Cancer Therapy von LEDGERWOOD, Elizabeth C, MORISON, Ian M

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Enhancing the peroxidase activity of cytochrome c by mutation of residue 41: implications for the peroxidase mechanism and cytochrome c release von Josephs, Tracy M, Morison, Ian M, Day, Catherine L, Wilbanks, Sigurd M, Ledgerwood, Elizabeth C

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Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1 von Weijman, Johannes F., Kumar, Abhishek, Jamieson, Sam A., King, Chontelle M., Caradoc-Davies, Tom T., Ledgerwood, Elizabeth C., Murphy, James M., Mace, Peter D.

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Rapid uptake of lipophilic triphenylphosphonium cations by mitochondria in vivo following intravenous injection: Implications for mitochondria-specific therapies and probes von Porteous, Carolyn M., Logan, Angela, Evans, Cameron, Ledgerwood, Elizabeth C., Menon, David K., Aigbirhio, Franklin, Smith, Robin A.J., Murphy, Michael P.

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Oxidation of mitochondrial peroxiredoxin 3 during the initiation of receptor-mediated apoptosis von Cox, Andrew G., Pullar, Juliet M., Hughes, Gillian, Ledgerwood, Elizabeth C., Hampton, Mark B.

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A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but causes only thrombocytopenia von da Silva Tatley, Fernanda M, Weeks, Robert J, Wilbanks, Sigurd M, Fagerlund, Robert D, Smith, Mark P, Davies, Stefan M K, Capron, Claude, Ledgerwood, Elizabeth C, Fichelson, Serge, Holyoake, Andrew J, Pippig, Diana A, Morison, Ian M, Cheesman, Emma J, Ludgate, Mathew W, Coker, Melanie S A, Bockett, Nicholas A, Cheong, Pak Leng, Hughes, Gillian, Lo, Alexandra, Cramer Bordé, Elisabeth M

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The Y49H cytochrome c variant enhances megakaryocytic maturation of K-562 cells von Shafaei Pishabad, Zahra, Ledgerwood, Elizabeth C.

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Interspecies Variation in the Functional Consequences of Mutation of Cytochrome c von Josephs, Tracy M, Hibbs, Moira E, Ong, Lily, Morison, Ian M, Ledgerwood, Elizabeth C

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The Proapoptotic G41S Mutation to Human Cytochrome c Alters the Heme Electronic Structure and Increases the Electron Self-Exchange Rate von Liptak, Matthew D, Fagerlund, Robert D, Ledgerwood, Elizabeth C, Wilbanks, Sigurd M, Bren, Kara L

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Altered conformational dynamics contribute to species-specific effects of cytochrome c mutations on caspase activation von Chin, Thomas C., Wilbanks, Sigurd M., Ledgerwood, Elizabeth C.

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The Structure and Ubiquitin Binding Properties of TRAF RING Heterodimers von Das, Anubrita, Middleton, Adam J., Padala, Prasanth, Ledgerwood, Elizabeth C., Mace, Peter D., Day, Catherine L.

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A Novel Bcl-2-Like Inhibitor of Apoptosis Is Encoded by the Parapoxvirus Orf Virus von WESTPHAL, Dana, LEDGERWOOD, Elizabeth C, HIBMA, Merilyn H, FLEMING, Stephen B, WHELAN, Ellena M, MERCER, Andrew A

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Inherited thrombocytopenia associated with a variant in the FLI1 binding site in the 5' UTR of ANKRD26 von Dunstan-Harrison, Caitlin, Morison, Ian M, Ledgerwood, Elizabeth C

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Megakaryocyte maturation involves activation of the adaptive unfolded protein response von Faiz, Mifra, Kalev‐Zylinska, Maggie L., Dunstan‐Harrison, Caitlin, Singleton, Dean C., Hay, Michael P., Ledgerwood, Elizabeth C.

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Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity von Fellner, Matthias, Parakra, Rinky, McDonald, Kirstin O, Kass, Itamar, Jameson, Guy N L, Wilbanks, Sigurd M, Ledgerwood, Elizabeth C

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A novel RNF125 variant associated with Tenorio syndrome alters ubiquitin chain binding von Barzak, Fareeda M., Lu, Anita, Geltzeiler, Alexa R., Ledgerwood, Elizabeth C., Chung, Wendy K., Day, Catherine L.

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