Increased cellular senescence and vascular rarefaction exacerbate the progression of kidney fibrosis in aged mice following transient ischemic injury von Clements, Meghan E, Chaber, Christopher J, Ledbetter, Steven R, Zuk, Anna

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Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models von Leonard, John P, Natoli, Thomas A, Rogers, Kelly A, Russo, Ryan J, Ibraghimov-Beskrovnaya, Oxana, Husson, Hervé, Budman, Yeva, Wang, Bing, Bukanov, Nikolay O, Smith, Laurie A, Belenky, Alexei, Komarnitsky, Svetlana, Shayman, James A, Ledbetter, Steven R, Dackowski, William R

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CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis von Bracken, Christina, Beauverger, Philippe, Duclos, Olivier, Russo, Ryan J, Rogers, Kelly A, Husson, Hervé, Natoli, Thomas A, Ledbetter, Steven R, Janiak, Philip, Ibraghimov-Beskrovnaya, Oxana, Bukanov, Nikolay O

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Blocking TGF-β Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFRβ+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury in Wistar M... von Pozdzik, Agnieszka A, Giordano, Laetitia, Li, Gang, Antoine, Marie-Hélène, Quellard, Nathalie, Godet, Julie, De Prez, Eric, Husson, Cécile, Declèves, Anne-Emilie, Arlt, Volker M, Goujon, Jean-Michel, Brochériou-Spelle, Isabelle, Ledbetter, Steven R, Caron, Nathalie, Nortier, Joëlle L

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CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD von Bukanov, Nikolay O., Moreno, Sarah E., Natoli, Thomas A., Rogers, Kelly A., Smith, Laurie A., Ledbetter, Steven R., Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Ibraghimov-Beskrovnaya, Oxana

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A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis von Trachtman, Howard, Fervenza, Fernando C., Gipson, Debbie S., Heering, Peter, Jayne, David R.W., Peters, Harm, Rota, Stefano, Remuzzi, Giuseppe, Rump, L. Christian, Sellin, Lorenz K., Heaton, Jeremy P.W., Streisand, James B., Hard, Marjie L., Ledbetter, Steven R., Vincenti, Flavio

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CXA-10, a Nitrated Fatty Acid, Is Renoprotective in Deoxycorticosterone Acetate-Salt Nephropathy von Arbeeny, Cynthia M, Ling, Hong, Smith, Mandy M, O'Brien, Stephen, Wawersik, Stefan, Ledbetter, Steven R, McAlexander, Allen, Schopfer, Francisco J, Willette, Robert N, Jorkasky, Diane K

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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis von Husson, Hervé, Moreno, Sarah, Smith, Laurie A, Smith, Mandy M, Russo, Ryan J, Pitstick, Rose, Sergeev, Mikhail, Ledbetter, Steven R, Bukanov, Nikolay O, Lane, Monica, Zhang, Kate, Billot, Katy, Carlson, George, Shah, Jagesh, Meijer, Laurent, Beier, David R, Ibraghimov-Beskrovnaya, Oxana

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Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine von Ledbetter, Steven R, Ibraghimov-Beskrovnaya, Oxana, Smith, Laurie A, Klinger, Katherine W, Bukanov, Nikolay O

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Role of TGF‐β in a Mouse Model of High Turnover Renal Osteodystrophy von Liu, Shiguang, Song, Wenping, Boulanger, Joseph H, Tang, Wen, Sabbagh, Yves, Kelley, Brian, Gotschall, Russell, Ryan, Susan, Phillips, Lucy, Malley, Katie, Cao, Xiaohong, Xia, Tai‐He, Zhen, Gehua, Cao, Xu, Ling, Hong, Dechow, Paul C, Bellido, Teresita M, Ledbetter, Steven R, Schiavi, Susan C

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Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury von Regner, Kevin R., Zuk, Anna, Van Why, Scott K., Shames, Brian D., Ryan, Robert P., Falck, John R., Manthati, Vijay L., McMullen, Meghan E., Ledbetter, Steven R., Roman, Richard J.

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Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease von NATOLI, Thomas A, HUSSON, Hervé, IBRAGHIMOV-BESKROVNAYA, Oxana, ROGERS, Kelly A, SMITH, Laurie A, BING WANG, BUDMAN, Yeva, BUKANOV, Nikolay O, LEDBETTER, Steven R, KLINGER, Katherine W, LEONARD, John P

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Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats von Murphy, Sydney R, Dahly-Vernon, Annette J, Dunn, Kathryn M J, Chen, Chun Cheng Andy, Ledbetter, Steven R, Williams, Jan M, Roman, Richard J

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Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction von El Chaar, Maher, Chen, Jie, Seshan, Surya V, Jha, Sharda, Richardson, Ingride, Ledbetter, Steven R, Vaughan, Jr, E D, Poppas, Dix P, Felsen, Diane

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Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD von Rogers, Kelly A., Moreno, Sarah E., Smith, Laurie A., Husson, Hervé, Bukanov, Nikolay O., Ledbetter, Steven R., Budman, Yeva, Lu, Yuefeng, Wang, Bing, Ibraghimov‐Beskrovnaya, Oxana, Natoli, Thomas A.

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Transforming Growth Factor-β, 20-HETE Interaction, and Glomerular Injury in Dahl Salt-Sensitive Rats von Dahly-Vernon, Annette J, Sharma, Mukut, McCarthy, Ellen T, Savin, Virginia J, Ledbetter, Steven R, Roman, Richard J

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Antihypertensive effects of chronic anti-TGF-beta antibody therapy in Dahl S rats von Dahly, Annette J, Hoagland, Kimberly M, Flasch, Averia K, Jha, Sharda, Ledbetter, Steven R, Roman, Richard J

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CXC Chemokines Connective Tissue Activating Peptide-III and Neutrophil Activating Peptide-2 are Heparin/Heparan Sulfate-degrading Enzymes (∗) von Hoogewerf, Arlene J., Leone, Joseph W., Reardon, Ilene M., Howe, W.Jeffrey, Asa, Darwin, Heinrikson, Robert L., Ledbetter, Steven R.

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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis von Husson, Hervé, Moreno, Sarah, Smith, Laurie A, Smith, Mandy M, Russo, Ryan J, Pitstick, Rose, Sergeev, Mikhail, Ledbetter, Steven R, Bukanov, Nikolay O, Lane, Monica, Zhang, Kate, Billot, Katy, Carlson, George, Shah, Jagesh, Meijer, Laurent, Beier, David R, Ibraghimov-Beskrovnaya, Oxana

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Blocking TGF-[beta] Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFR[beta]+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury i... von Pozdzik, Agnieszka A, Giordano, Laetitia, Li, Gang, Antoine, Marie-Hélène, Quellard, Nathalie, Godet, Julie, De Prez, Eric, Husson, Cécile, Declèves, Anne-Emilie, Arlt, Volker M, Goujon, Jean-Michel, Brochériou-Spelle, Isabelle, Ledbetter, Steven R, Caron, Nathalie, Nortier, Joëlle L

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