Mutation in TET2 in Myeloid Cancers von Delhommeau, François, Dupont, Sabrina, Valle, Véronique Della, James, Chloé, Trannoy, Severine, Massé, Aline, Kosmider, Olivier, Le Couedic, Jean-Pierre, Robert, Fabienne, Alberdi, Antonio, Lécluse, Yann, Plo, Isabelle, Dreyfus, François J, Marzac, Christophe, Casadevall, Nicole, Lacombe, Catherine, Romana, Serge P, Dessen, Philippe, Soulier, Jean, Viguié, Franck, Fontenay, Michaela, Vainchenker, William, Bernard, Olivier A

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CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia von Allouch, Awatef, Voisin, Laurent, Zhang, Yanyan, Raza, Syed Qasim, Lecluse, Yann, Calvo, Julien, Selimoglu-Buet, Dorothée, de Botton, Stéphane, Louache, Fawzia, Pflumio, Françoise, Solary, Eric, Perfettini, Jean-Luc

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The formin DIAPH1 (mDia1) regulates megakaryocyte proplatelet formation by remodeling the actin and microtubule cytoskeletons von Pan, Jiajia, Lordier, Larissa, Meyran, Deborah, Rameau, Philippe, Lecluse, Yann, Kitchen-Goosen, Susan, Badirou, Idinath, Mokrani, Hayat, Narumiya, Shuh, Alberts, Arthur S., Vainchenker, William, Chang, Yunhua

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Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models von Thiollier, Clarisse, Lopez, Cécile K, Gerby, Bastien, Ignacimouttou, Cathy, Poglio, Sandrine, Duffourd, Yannis, Guégan, Justine, Rivera-Munoz, Paola, Bluteau, Olivier, Mabialah, Vinciane, Diop, M'boyba, Wen, Qiang, Petit, Arnaud, Bauchet, Anne-Laure, Reinhardt, Dirk, Bornhauser, Beat, Gautheret, Daniel, Lecluse, Yann, Landman-Parker, Judith, Radford, Isabelle, Vainchenker, William, Dastugue, Nicole, de Botton, Stéphane, Dessen, Philippe, Bourquin, Jean-Pierre, Crispino, John D, Ballerini, Paola, Bernard, Olivier A, Pflumio, Françoise, Mercher, Thomas

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Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia von Lopez, Cécile K, Noguera, Esteve, Stavropoulou, Vaia, Robert, Elie, Aid, Zakia, Ballerini, Paola, Bilhou-Nabera, Chrystèle, Lapillonne, Hélène, Boudia, Fabien, Thirant, Cécile, Fagnan, Alexandre, Arcangeli, Marie-Laure, Kinston, Sarah J, Diop, M'Boyba, Job, Bastien, Lecluse, Yann, Brunet, Erika, Babin, Loélia, Villeval, Jean Luc, Delabesse, Eric, Peters, Antoine H F M, Vainchenker, William, Gaudry, Muriel, Masetti, Riccardo, Locatelli, Franco, Malinge, Sébastien, Nerlov, Claus, Droin, Nathalie, Lobry, Camille, Godin, Isabelle, Bernard, Olivier A, Göttgens, Berthold, Petit, Arnaud, Pflumio, Françoise, Schwaller, Juerg, Mercher, Thomas

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A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell–derived primitive hematopoiesis von Klimchenko, Olena, Mori, Marcella, DiStefano, Antonio, Langlois, Thierry, Larbret, Frédéric, Lecluse, Yann, Feraud, Olivier, Vainchenker, William, Norol, Françoise, Debili, Najet

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Circulating tumor cell copy-number heterogeneity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors von Oulhen, Marianne, Pawlikowska, Patrycja, Tayoun, Tala, Garonzi, Marianna, Buson, Genny, Forcato, Claudio, Manaresi, Nicolò, Aberlenc, Agathe, Mezquita, Laura, Lecluse, Yann, Lavaud, Pernelle, Naltet, Charles, Planchard, David, Besse, Benjamin, Farace, Françoise

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A senescence-like cell-cycle arrest occurs during megakaryocytic maturation: implications for physiological and pathological megakaryocytic proliferation von Besancenot, Rodolphe, Chaligné, Ronan, Tonetti, Carole, Pasquier, Florence, Marty, Caroline, Lécluse, Yann, Vainchenker, William, Constantinescu, Stefan N, Giraudier, Stéphane

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JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation von Besancenot, Rodolphe, Roos-Weil, Damien, Tonetti, Carole, Abdelouahab, Hadjer, Lacout, Catherine, Pasquier, Florence, Willekens, Christophe, Rameau, Philippe, Lecluse, Yann, Micol, Jean-Baptiste, Constantinescu, Stefan N., Vainchenker, William, Solary, Eric, Giraudier, Stéphane

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Isolation of tumor-resident CD8+ T cells from human lung tumors von Corgnac, Stéphanie, Lecluse, Yann, Mami-chouaib, Fathia

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Nfkbie-deficiency leads to increased susceptibility to develop B-cell lymphoproliferative disorders in aged mice von Della-Valle, Veronique, Roos-Weil, Damien, Scourzic, Laurianne, Mouly, Enguerran, Aid, Zakia, Darwiche, Walaa, Lecluse, Yann, Damm, Frederik, Mémet, Sylvie, Mercher, Thomas, Aoufouchi, Said, Nguyen-Khac, Florence, Bernard, Olivier A., Ghamlouch, Hussein

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Lyl-1 regulates primitive macrophages and microglia development von Wang, Shoutang, Ren, Deshan, Arkoun, Brahim, Kaushik, Anna-Lila, Matherat, Gabriel, Lécluse, Yann, Filipp, Dominik, Vainchenker, William, Raslova, Hana, Plo, Isabelle, Godin, Isabelle

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Rescue of tumor-infiltrating lymphocytes from activation-induced cell death enhances the antitumor CTL response in CD5-deficient mice von Tabbekh, Mouna, Franciszkiewicz, Katarzyna, Haouas, Houda, Lécluse, Yann, Benihoud, Karim, Raman, Chander, Mami-Chouaib, Fathia

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The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera von Dupont, Sabrina, Massé, Aline, James, Chloé, Teyssandier, Irène, Lécluse, Yann, Larbret, Frédéric, Ugo, Valérie, Saulnier, Patrick, Koscielny, Serge, Le Couédic, Jean Pierre, Casadevall, Nicole, Vainchenker, William, Delhommeau, François

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Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4–/– chimeric mice von Foudi, Adlen, Jarrier, Peggy, Zhang, Yanyan, Wittner, Monika, Geay, Jean-Francois, Lecluse, Yann, Nagasawa, Takashi, Vainchenker, William, Louache, Fawzia

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Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis von Chaligné, Ronan, James, Chloé, Tonetti, Carole, Besancenot, Rodolphe, Le Couédic, Jean Pierre, Fava, Fanny, Mazurier, Fréderic, Godin, Isabelle, Maloum, Karim, Larbret, Frédéric, Lécluse, Yann, Vainchenker, William, Giraudier, Stéphane

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Overexpression of Insulin Receptor Substrate-2 in Human and Murine Hepatocellular Carcinoma von Boissan, Mathieu, Beurel, Eléonore, Wendum, Dominique, Rey, Colette, Lécluse, Yann, Housset, Chantal, Lacombe, Marie-Lise, Desbois-Mouthon, Christèle

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The SCL relative LYL-1 is required for fetal and adult hematopoietic stem cell function and B-cell differentiation von Capron, Claude, Lécluse, Yann, Kaushik, Anna Lila, Foudi, Adlen, Lacout, Catherine, Sekkai, Dalila, Godin, Isabelle, Albagli, Olivier, Poullion, Isabelle, Svinartchouk, Fedor, Schanze, Elisabeth, Vainchenker, William, Sablitzky, Fred, Bennaceur-Griscelli, Annelise, Duménil, Dominique

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Multimodal imaging for tumour characterization from micro‐ to macroscopic level using a newly developed dorsal chamber designed for long‐term follow‐up von Rouffiac, Valérie, Roux, Karine Ser‐Le, Salomé‐Desnoulez, Sophie, Leguerney, Ingrid, Ginefri, Jean‐Christophe, Sébrié, Catherine, Jourdain, Laurène, Lécluse, Yann, Laplace‐Builhé, Corinne

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NK Cells Infiltrating a MHC Class I-Deficient Lung Adenocarcinoma Display Impaired Cytotoxic Activity toward Autologous Tumor Cells Associated with Altered NK Cell-Triggering Recep... von Le Maux Chansac, Beatrice, Moretta, Alessandro, Vergnon, Isabelle, Opolon, Paule, Lecluse, Yann, Grunenwald, Dominique, Kubin, Marek, Soria, Jean-Charles, Chouaib, Salem, Mami-Chouaib, Fathia

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