Palladium-Catalyzed Cross-Coupling Reactions of Diazine N-Oxides with Aryl Chlorides, Bromides, and Iodides von Leclerc, Jean-Philippe, Fagnou, Keith

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CpRh(III)‐Catalyzed C8 C−H Alkylation of Quinoline N‐Oxides with Diazo Meldrum's Acid von Huestis, Malcolm P., Leclerc, Jean‐Philippe, Larouche‐Gauthier, Robin, Aubert‐Nicol, Samuel, Yadav, Arun, Sivamuthuraman, Koilpitchai

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Palladium-Catalyzed Direct Arylation of Azine and Azole N-Oxides: Reaction Development, Scope and Applications in Synthesis von Campeau, Louis-Charles, Stuart, David R., Leclerc, Jean-Philippe, Bertrand-Laperle, Mégan, Villemure, Elisia, Sun, Ho-Yan, Lasserre, Sandrine, Guimond, Nicolas, Lecavallier, Melanie, Fagnou, Keith

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C2, C5, and C4 Azole N-Oxide Direct Arylation Including Room-Temperature Reactions von Campeau, Louis-Charles, Bertrand-Laperle, Mégan, Leclerc, Jean-Philippe, Villemure, Elisia, Gorelsky, Serge, Fagnou, Keith

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Discovery of Potent, Selective, and Orally Available IRE1α Inhibitors Demonstrating Comparable PD Modulation to IRE1 Knockdown in a Multiple Myeloma Model von Braun, Marie-Gabrielle, Ashkenazi, Avi, Beveridge, Ramsay E., Castanedo, Georgette, Wallweber, Heidi Ackerly, Beresini, Maureen H., Clark, Kevin R., De Bruyn, Tom, Fu, Liqiang, Gibbons, Paul, Jiang, Fan, Kaufman, Susan, Kan, David, Kiefer, James R., Leclerc, Jean-Philippe, Lemire, Alexandre, Ly, Cuong, Segal, Ehud, Sims, Jessica, Wang, Weiru, Wei, Wentao, Zhao, Liang, Schwarz, Jacob B., Rudolph, Joachim

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Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma von Bronner, Sarah M., Merrick, Karl A., Murray, Jeremy, Salphati, Laurent, Moffat, John G., Pang, Jodie, Sneeringer, Christopher J., Dompe, Nicholas, Cyr, Patrick, Purkey, Hans, Boenig, Gladys de Leon, Li, Jun, Kolesnikov, Aleksandr, Larouche-Gauthier, Robin, Lai, Kwong Wah, Shen, Xiaoli, Aubert-Nicol, Samuel, Chen, Yi-Chen, Cheong, Jonathan, Crawford, James J., Hafner, Marc, Haghshenas, Pouyan, Jakalian, Araz, Leclerc, Jean-Philippe, Lim, Ngiap-Kie, O'Brien, Tom, Plise, Emile G., Shalan, Hadil, Sturino, Claudio, Wai, John, Xiao, Yang, Yin, Jianping, Zhao, Liang, Gould, Stephen, Olivero, Alan, Heffron, Timothy P.

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Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2) von Zeng, Mingshuo, Grandner, Jessica M., Bryan, Marian C., Verma, Vishal, Larouche-Gauthier, Robin, Leclerc, Jean-Philippe, Zhao, Liang, Haghshenas, Pouyan, Aubert-Nicol, Samuel, Yadav, Arun, Ashley, Melissa, Chen, Jacob Z., Durk, Matthew, Samy, Karen E., Nespi, Marika, Levy, Elizabeth, Merrick, Karl, Moffat, John G., Murray, Jeremy, Oh, Angela, Orr, Christine, Segal, Ehud, Sims, Jessica, Sneeringer, Christopher, Prangley, Madeleine, Vartanian, Steffan, Magnuson, Steven, Parr, Brendan T.

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Heck, Direct Arylation, and Hydrogenation: Two or Three Sequential Reactions from a Single Catalyst von Leclerc, Jean-Philippe, André, Mathieu, Fagnou, Keith

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Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity von Beveridge, Ramsay E, Wallweber, Heidi Ackerly, Ashkenazi, Avi, Beresini, Maureen, Clark, Kevin R, Gibbons, Paul, Ghiro, Elise, Kaufman, Susan, Larivée, Alexandre, Leblanc, Melissa, Leclerc, Jean-Philippe, Lemire, Alexandre, Ly, Cuong, Rudolph, Joachim, Schwarz, Jacob B, Srivastava, Sanjay, Wang, Weiru, Zhao, Liang, Braun, Marie-Gabrielle

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Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series von Lachance, Nicolas, Gareau, Yves, Guiral, Sébastien, Huang, Zheng, Isabel, Elise, Leclerc, Jean-Philippe, Léger, Serge, Martins, Evelyn, Nadeau, Christian, Oballa, Renata M., Ouellet, Stéphane G., Powell, David A., Ramtohul, Yeeman K., Tranmer, Geoffrey K., Trinh, Thao, Wang, Hao, Zhang, Lei

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Bicyclic heteroaryl inhibitors of stearoyl-CoA desaturase: From systemic to liver-targeting inhibitors von Ramtohul, Yeeman K., Powell, David, Leclerc, Jean-Philippe, Leger, Serge, Oballa, Renata, Black, Cameron, Isabel, Elise, Li, Chun Sing, Crane, Sheldon, Robichaud, Joel, Guay, Jocelyne, Guiral, Sébastien, Zhang, Lei, Huang, Zheng

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Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series von Lachance, Nicolas, Guiral, Sébastien, Huang, Zheng, Leclerc, Jean-Philippe, Li, Chun Sing, Oballa, Renata M., Ramtohul, Yeeman K., Wang, Hao, Wu, Jin, Zhang, Lei

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Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors von Leclerc, Jean-Philippe, Falgueyret, Jean-Pierre, Girardin, Mélina, Guay, Jocelyne, Guiral, Sébastien, Huang, Zheng, Li, Chun Sing, Oballa, Renata, Ramtohul, Yeeman K., Skorey, Kathryn, Tawa, Paul, Wang, Hao, Zhang, Lei

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The Hemetsberger-Knittel Synthesis of Substituted 5-, 6-, and 7-Azaindoles von Roy, Patrick J., Dufresne, Claude, Lachance, Nicolas, Leclerc, Jean-Philippe, Boisvert, Michel, Wang, Zhaoyin, Leblanc, Yves

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Cover Feature: CpRh(III)‐Catalyzed C8 C−H Alkylation of Quinoline N‐Oxides with Diazo Meldrum's Acid (Eur. J. Org. Chem. 3/2021) von Huestis, Malcolm P., Leclerc, Jean‐Philippe, Larouche‐Gauthier, Robin, Aubert‐Nicol, Samuel, Yadav, Arun, Sivamuthuraman, Koilpitchai

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Palladium-Catalyzed Cross-Coupling Reactions of Diazine N-Oxides with Aryl Chlorides, Bromides, and Iodides von Leclerc, Jean-Philippe, Fagnou, Keith

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Optimization of a Novel DEL Hit That Binds in the Cbl‑b SH2 Domain and Blocks Substrate Binding von Liang, Jun, Lambrecht, Michael J., Arenzana, Teresita L., Aubert-Nicol, Samuel, Bao, Linda, Broccatelli, Fabio, Cai, Jianping, Eidenschenk, Celine, Everett, Christine, Garner, Thomas, Gruber, Felix, Haghshenas, Pouyan, Huestis, Malcolm P., Hsu, Peter L., Kou, Ponien, Jakalian, Araz, Larouche-Gauthier, Robin, Leclerc, Jean-Philippe, Leung, Dennis H., Martin, Aaron, Murray, Jeremy, Prangley, Madeleine, Rutz, Sascha, Kakiuchi-Kiyota, Satoko, Satz, Alexander Lee, Skelton, Nicholas J., Steffek, Micah, Stoffler, Daniel, Sudhamsu, Jawahar, Tan, Sophia, Wang, Jian, Wang, Shouliang, Wang, Qiuyue, Wendorff, Timothy J., Wichert, Moreno, Yadav, Arun, Yu, Christine, Wang, Xiaojing

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Palladium-Catalyzed Cross-Coupling Reactions of Diazine N-Oxides with Aryl Chlorides, Bromides, and Iodides von Leclerc, Jean-Philippe, Fagnou, Keith

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Heck, Direct Arylation, and Hydrogenation: Two or Three Sequential Reactions from a Single Catalyst von Leclerc, Jean-Philippe, Andre, Mathieu, Fagnou, Keith

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PROCESS OF CHOCOLATE PRODUCTION von LECLERC, Jean-Philippe

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