Synthesis and Biological Activity of Sterol 14α-Demethylase and Sterol C24-Methyltransferase Inhibitors von Leaver, David J

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Unearthing the Janus-face cholesterogenesis pathways in cancer von Madan, Babita, Virshup, David M., Nes, W. David, Leaver, David J.

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Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells von Santori, Fabio R., Huang, Pengxiang, van de Pavert, Serge A., Douglass, Eugene F., Leaver, David J., Haubrich, Brad A., Keber, Rok, Lorbek, Gregor, Konijn, Tanja, Rosales, Brittany N., Rozman, Damjana, Horvat, Simon, Rahier, Alain, Mebius, Reina E., Rastinejad, Fraydoon, Nes, W. David, Littman, Dan R.

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Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth von Baell, Jonathan B., Leaver, David J., Hermans, Stefan J., Kelly, Gemma L., Brennan, Margs S., Downer, Natalie L., Nguyen, Nghi, Wichmann, Johannes, McRae, Helen M., Yang, Yuqing, Cleary, Ben, Lagiakos, H. Rachel, Mieruszynski, Stephen, Pacini, Guido, Vanyai, Hannah K., Bergamasco, Maria I., May, Rose E., Davey, Bethany K., Morgan, Kimberly J., Sealey, Andrew J., Wang, Beinan, Zamudio, Natasha, Wilcox, Stephen, Garnham, Alexandra L., Sheikh, Bilal N., Aubrey, Brandon J., Doggett, Karen, Chung, Matthew C., de Silva, Melanie, Bentley, John, Pilling, Pat, Hattarki, Meghan, Dolezal, Olan, Dennis, Matthew L., Falk, Hendrik, Ren, Bin, Charman, Susan A., White, Karen L., Rautela, Jai, Newbold, Andrea, Hawkins, Edwin D., Johnstone, Ricky W., Huntington, Nicholas D., Peat, Thomas S., Heath, Joan K., Strasser, Andreas, Parker, Michael W., Smyth, Gordon K., Street, Ian P., Monahan, Brendon J., Voss, Anne K., Thomas, Tim

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HBO1 is required for the maintenance of leukaemia stem cells von MacPherson, Laura, Anokye, Juliana, Yeung, Miriam M., Lam, Enid Y. N., Chan, Yih-Chih, Weng, Chen-Fang, Yeh, Paul, Knezevic, Kathy, Butler, Miriam S., Hoegl, Annabelle, Chan, Kah-Lok, Burr, Marian L., Gearing, Linden J., Willson, Tracy, Liu, Joy, Choi, Jarny, Yang, Yuqing, Bilardi, Rebecca A., Falk, Hendrik, Nguyen, Nghi, Stupple, Paul A., Peat, Thomas S., Zhang, Ming, de Silva, Melanie, Carrasco-Pozo, Catalina, Avery, Vicky M., Khoo, Poh Sim, Dolezal, Olan, Dennis, Matthew L., Nuttall, Stewart, Surjadi, Regina, Newman, Janet, Ren, Bin, Leaver, David J., Sun, Yuxin, Baell, Jonathan B., Dovey, Oliver, Vassiliou, George S., Grebien, Florian, Dawson, Sarah-Jane, Street, Ian P., Monahan, Brendon J., Burns, Christopher J., Choudhary, Chunaram, Blewitt, Marnie E., Voss, Anne K., Thomas, Tim, Dawson, Mark A.

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Druggable Sterol Metabolizing Enzymes in Infectious Diseases: Cell Targets to Therapeutic Leads von Nes, W David, Chaudhuri, Minu, Leaver, David J

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A nematode sterol C4α-methyltransferase catalyzes a new methylation reaction responsible for sterol diversity[S] von Zhou, Wenxu, Fisher, Paxtyn M., Vanderloop, Boden H., Shen, Yun, Shi, Huazhong, Maldonado, Adrian J., Leaver, David J., Nes, W. David

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The influence of residential and workday population mobility on exposure to air pollution in the UK von Reis, Stefan, Liška, Tomáš, Vieno, Massimo, Carnell, Edward J., Beck, Rachel, Clemens, Tom, Dragosits, Ulrike, Tomlinson, Samuel J., Leaver, David, Heal, Mathew R.

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Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth[S] von Haubrich, Brad A., Singha, Ujjal K., Miller, Matthew B., Nes, Craigen R., Anyatonwu, Hosanna, Lecordier, Laurence, Patkar, Presheet, Leaver, David J., Villalta, Fernando, Vanhollebeke, Benoit, Chaudhuri, Minu, Nes, W. David

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Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A von Leaver, David J, Cleary, Benjamin, Nguyen, Nghi, Priebbenow, Daniel L, Lagiakos, H. Rachel, Sanchez, Julie, Xue, Lian, Huang, Fei, Sun, Yuxin, Mujumdar, Prashant, Mudududdla, Ramesh, Varghese, Swapna, Teguh, Silvia, Charman, Susan A, White, Karen L, Katneni, Kasiram, Cuellar, Matthew, Strasser, Jessica M, Dahlin, Jayme L, Walters, Michael A, Street, Ian P, Monahan, Brendon J, Jarman, Kate E, Sabroux, Helene Jousset, Falk, Hendrik, Chung, Matthew C, Hermans, Stefan J, Parker, Michael W, Thomas, Tim, Baell, Jonathan B

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Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents von Priebbenow, Daniel L, Leaver, David J, Nguyen, Nghi, Cleary, Benjamin, Lagiakos, H. Rachel, Sanchez, Julie, Xue, Lian, Huang, Fei, Sun, Yuxin, Mujumdar, Prashant, Mudududdla, Ramesh, Varghese, Swapna, Teguh, Silvia, Charman, Susan A, White, Karen L, Shackleford, David M, Katneni, Kasiram, Cuellar, Matthew, Strasser, Jessica M, Dahlin, Jayme L, Walters, Michael A, Street, Ian P, Monahan, Brendon J, Jarman, Kate E, Jousset Sabroux, Helene, Falk, Hendrik, Chung, Matthew C, Hermans, Stefan J, Downer, Natalie L, Parker, Michael W, Voss, Anne K, Thomas, Tim, Baell, Jonathan B

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Inertia in an ombrotrophic bog ecosystem in response to 9 years' realistic perturbation by wet deposition of nitrogen, separated by form von Sheppard, Lucy J., Leith, Ian D., Mizunuma, Toshie, Leeson, Sarah, Kivimaki, Sanna, Neil Cape, J., van Dijk, Netty, Leaver, David, Sutton, Mark A., Fowler, David, Van den Berg, Leon J.L., Crossley, Alan, Field, Chris, Smart, Simon

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Synthesis of 1,2,3-triazole linked galactopyranosides and evaluation of cholera toxin inhibition von Leaver, David J, Dawson, Raymond M, White, Jonathan M, Polyzos, Anastasios, Hughes, Andrew B

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Synthesis of RAFT polymers as bivalent inhibitors of cholera toxin von Leaver, David J, Hughes, Andrew B, Dawson, Raymond M, Postma, Almar, Malic, Nino, Polyzos, Anastasios

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Pan-European rural monitoring network shows dominance of NH3 gas and NH4NO3 aerosol in inorganic atmospheric pollution load von Y Sim Tang, Flechard, Chris R, Dämmgen, Ulrich, Vidic, Sonja, Djuricic, Vesna, Mitosinkova, Marta, Uggerud, Hilde T, Sanz, Maria J, Simmons, Ivan, Dragosits, Ulrike, Nemitz, Eiko, Twigg, Marsailidh, Netty van Dijk, Fauvel, Yannick, Sanz, Francisco, Ferm, Martin, Perrino, Cinzia, Catrambone, Maria, Leaver, David, Braban, Christine F, Cape, J Neil, Heal, Mathew R, Sutton, Mark A

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Acid gases and aerosol measurements in the UK (1999–2015): regional distributions and trends von Tang, Y. Sim, Braban, Christine F., Dragosits, Ulrike, Simmons, Ivan, Leaver, David, van Dijk, Netty, Poskitt, Janet, Thacker, Sarah, Patel, Manisha, Carter, Heather, Pereira, M. Glória, Keenan, Patrick O., Lawlor, Alan, Conolly, Christopher, Vincent, Keith, Heal, Mathew R., Sutton, Mark A.

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Pan-European rural monitoring network shows dominance of NH.sub.3 gas and NH.sub.4NO.sub.3 aerosol in inorganic atmospheric pollution load von Tang, Y. Sim, Flechard, Chris R, Dämmgen, Ulrich, Vidic, Sonja, Djuricic, Vesna, Mitosinkova, Marta, Uggerud, Hilde T, Sanz, Maria J, Simmons, Ivan, Dragosits, Ulrike, Nemitz, Eiko, Twigg, Marsailidh, van Dijk, Netty, Fauvel, Yannick, Sanz, Francisco, Ferm, Martin, Perrino, Cinzia, Catrambone, Maria, Leaver, David, Braban, Christine F, Cape, J. Neil, Heal, Mathew R, Sutton, Mark A

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Pan-European rural monitoring network shows dominance of NH 3 gas and NH 4 NO 3 aerosol in inorganic atmospheric pollution load von Tang, Y. Sim, Flechard, Chris R., Dämmgen, Ulrich, Vidic, Sonja, Djuricic, Vesna, Mitosinkova, Marta, Uggerud, Hilde T., Sanz, Maria J., Simmons, Ivan, Dragosits, Ulrike, Nemitz, Eiko, Twigg, Marsailidh, van Dijk, Netty, Fauvel, Yannick, Sanz, Francisco, Ferm, Martin, Perrino, Cinzia, Catrambone, Maria, Leaver, David, Braban, Christine F., Cape, J. Neil, Heal, Mathew R., Sutton, Mark A.

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Pan-European rural monitoring network shows dominance of NH3 gas and NH4NO3 aerosol in inorganic atmospheric pollution load von Tang, Y. Sim, Flechard, Chris R., Dämmgen, Ulrich, Vidic, Sonja, Djuricic, Vesna, Mitosinkova, Marta, Uggerud, Hilde Thelle, Sanz, Maria J., Simmons, Ivan, Dragosits, Ulrike, Nemitz, Eiko, Twigg, Marsailidh, van Dijk, Netty, Fauvel, Yannick, Sanz, Francisco, Ferm, Martin, Perrino, Cinzia, Catrambone, Maria, Leaver, David, Braban, Christine F., Cape, J. Neil, Heal, Mathew R., Sutton, Mark A.

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Fluorinated Sterols Are Suicide Inhibitors of Ergosterol Biosynthesis and Growth in Trypanosoma brucei von Leaver, David J., Patkar, Presheet, Singha, Ujjal K., Miller, Matthew B., Haubrich, Brad A., Chaudhuri, Minu, Nes, W. David

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