KPNB1-mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells von Stelma, Tamara, Leaner, Virna D

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Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity von van der Watt, Pauline J, Ngarande, Ellen, Leaner, Virna D

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Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential von Stelma, Tamara, Chi, Alicia, van der Watt, Pauline J., Verrico, Annalisa, Lavia, Patrizia, Leaner, Virna D.

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The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation von van der Watt, Pauline J., Maske, Christopher P., Hendricks, Denver T., Parker, M. Iqbal, Denny, Lynette, Govender, Dhirendra, Birrer, Michael J., Leaner, Virna D.

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Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic von van der Watt, Pauline J, Chi, Alicia, Stelma, Tamara, Stowell, Catherine, Strydom, Erin, Carden, Sarah, Angus, Liselotte, Hadley, Kate, Lang, Dirk, Wei, Wei, Birrer, Michael J, Trent, John O, Leaner, Virna D

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Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer von Chi, Ru-Pin Alicia, van der Watt, Pauline, Wei, Wei, Birrer, Michael J, Leaner, Virna D

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A mass spectrometry-based approach for the identification of Kpnβ1 binding partners in cancer cells von Okpara, Michael O., Hermann, Clemens, van der Watt, Pauline J., Garnett, Shaun, Blackburn, Jonathan M., Leaner, Virna D.

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Inhibition of the nuclear transporter, Kpnβ1, results in prolonged mitotic arrest and activation of the intrinsic apoptotic pathway in cervical cancer cells von Angus, Liselotte, van der Watt, Pauline J., Leaner, Virna D.

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A tight balance of Karyopherin β1 expression is required in cervical cancer cells von Carden, Sarah, van der Watt, Pauline, Chi, Alicia, Ajayi-Smith, Aderonke, Hadley, Katie, Leaner, Virna D

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Absence of feedback regulation in the synthesis of COL1A1 von Dzobo, Kevin, Leaner, Virna D., Parker, M. Iqbal

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PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration von Mowla, Shaheen, Pinnock, Romaney, Leaner, Virna D, Goding, Colin R, Prince, Sharon

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The nuclear exporter, Crm1, is regulated by NFY and Sp1 in cancer cells and repressed by p53 in response to DNA damage von van der Watt, Pauline J., Leaner, Virna D.

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p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts von Holderness Parker, Nina, Donninger, Howard, Birrer, Michael J, Leaner, Virna D

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Feedback regulation of the α2(1) collagen gene via the Mek–Erk signaling pathway von Dzobo, Kevin, Leaner, Virna D., Parker, M. Iqbal

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Therapeutic targeting of nuclear export and import receptors in cancer and their potential in combination chemotherapy von Newell, Stella, Watt, Pauline J., Leaner, Virna D.

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Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells von Ajayi-Smith, Aderonke, van der Watt, Pauline, Mkwanazi, Nonkululeko, Carden, Sarah, Trent, John O., Leaner, Virna D.

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Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers von Watt, Pauline J., Okpara, Michael O., Wishart, Andrew, Parker, M. Iqbal, Soares, Nelson C., Blackburn, Jonathan M., Leaner, Virna D.

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Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes von van der Watt, Pauline J., Roden, Laura C., Davis, Kate T., Parker, M. Iqbal, Leaner, Virna D.

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The tumour suppressing role of the circadian clock von Davis, Kate, Roden, Laura C., Leaner, Virna D., Watt, Pauline J.

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The Karyopherin proteins, Crm1 and Karyopherin beta 1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation von van der Watt, Pauline J, Maske, Christopher P, Hendricks, Denver T, Parker, M Iqbal, Denny, Lynette, Govender, Dhirendra, Birrer, Michael J, Leaner, Virna D

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