A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance von Chauhan, Dharminder, Tian, Ze, Nicholson, Benjamin, Kumar, K.G. Suresh, Zhou, Bin, Carrasco, Ruben, McDermott, Jeffrey L., Leach, Craig A., Fulcinniti, Mariaterresa, Kodrasov, Matthew P., Weinstock, Joseph, Kingsbury, William D., Hideshima, Teru, Shah, Parantu K., Minvielle, Stephane, Altun, Mikael, Kessler, Benedikt M., Orlowski, Robert, Richardson, Paul, Munshi, Nikhil, Anderson, Kenneth C.

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The Ubiquitin-Specific Protease USP34 Regulates Axin Stability and Wnt/β-Catenin Signaling von Lui, Tony T. H., Lacroix, Celine, Ahmed, Syed M., Goldenberg, Seth J., Leach, Craig A., Daulat, Avais M., Angers, Stephane

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The CCR2/MCP-1 Chemokine Pathway and Lung Adenocarcinoma von Mittal, Payal, Wang, Liqing, Akimova, Tatiana, Leach, Craig A, Clemente, Jose C, Sender, Matthew R, Chen, Yao, Turunen, Brandon J, Hancock, Wayne W

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Ubiquitin/SUMO modification of PCNA promotes replication fork progression in Xenopus laevis egg extracts von Leach, Craig A, Michael, W. Matthew

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Characterization of ubiquitin and ubiquitin‐like‐protein isopeptidase activities von Nicholson, Benjamin, Leach, Craig A., Goldenberg, Seth J., Francis, Dana M., Kodrasov, Matthew P., Tian, Xufan, Shanks, John, Sterner, David E., Bernal, Alejandro, Mattern, Michael R., Wilkinson, Keith D., Butt, Tauseef R.

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Regulatory Monoubiquitination of Phosphoenolpyruvate Carboxylase in Germinating Castor Oil Seeds von Uhrig, R. Glen, She, Yi-Min, Leach, Craig A., Plaxton, William C.

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Tissue-specific expression and post-translational modifications of plant- and bacterial-type phosphoenolpyruvate carboxylase isozymes of the castor oil plant, Ricinus communis L von O'Leary, Brendan, Fedosejevs, Eric T., Hill, Allyson T., Bettridge, James, Park, Joonho, Rao, Srinath K., Leach, Craig A., Plaxton, William C.

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Bioluminescence assay platform for selective and sensitive detection of Ub/Ubl proteases von Orcutt, Steven J., Wu, Jian, Eddins, Michael J., Leach, Craig A., Strickler, James E.

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Activation of Aurora-A Kinase by Protein Phosphatase Inhibitor-2, a Bifunctional Signaling Protein von Satinover, David L., Leach, Craig A., Stukenberg, P. Todd, Brautigan, David L., Ruderman, Joan V.

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Targeting the Ubiquitin E3 Ligase MuRF1 to Inhibit Muscle Atrophy von Eddins, Michael J., Marblestone, Jeffrey G., Suresh Kumar, K. G., Leach, Craig A., Sterner, David E., Mattern, Michael R., Nicholson, Benjamin

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Analysis of ubiquitin E3 ligase activity using selective polyubiquitin binding proteins von Marblestone, Jeffrey G., LaRocque, James P., Mattern, Michael R., Leach, Craig A.

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Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format von Tian, Xufan, Isamiddinova, Nigora S, Peroutka, Raymond J, Goldenberg, Seth J, Mattern, Michael R, Nicholson, Benjamin, Leach, Craig

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Deubiquitylase, DeSUMOylase, and DeISGylase Activity Microarrays for Assay of Substrate Preference and Functional Modifiers von Loch, Christian M., Cuccherini, Charles L., Leach, Craig A., Strickler, James E.

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Detection and Characterization of SUMO Protease Activity Using a Sensitive Enzyme-Based Reporter Assay von Leach, Craig A., Tian, Xufan, Mattern, Michael R., Nicholson, Benjamin

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Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes von Altun, Mikael, Kramer, Holger B., Willems, Lianne I., McDermott, Jeffrey L., Leach, Craig A., Goldenberg, Seth J., Kumar, K.G. Suresh, Konietzny, Rebecca, Fischer, Roman, Kogan, Edward, Mackeen, Mukram M., McGouran, Joanna, Khoronenkova, Svetlana V., Parsons, Jason L., Dianov, Grigory L., Nicholson, Benjamin, Kessler, Benedikt M.

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A Baker’s Dozen of Ubiquitin von Haas, Arthur L., Leach, Craig A.

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Phosphorylation of Phosphatase Inhibitor-2 at Centrosomes during Mitosis von Leach, Craig, Shenolikar, Shirish, Brautigan, David L.

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Novel Approach for Characterizing Ubiquitin E3 Ligase Function von Marblestone, Jeffrey G., Suresh Kumar, K.G., Eddins, Michael J., Leach, Craig A., Sterner, David E., Mattern, Michael R., Nicholson, Benjamin

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Targeting Chemokine Receptors to Modulate MDSCs for Cancer Therapy von Mittal, Payal, Leach, Craig, Clemente, Jose, Sender, Mathew, Hancock, Wayne W., Turunen, Brandon

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Abstract 1965: Inhibiting the CCR2/MCP-1 chemokine pathway blocks MDSC recruitment and promotes anti-tumor immunity von Mittal, Payal, Wang, Liqing, Akimova, Tatiana, Leach, Craig A., Clemente, Jose C., Sender, Mathew, Chen, Yao, Turenen, Brandon, Hancock, Wayne W.

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