Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and Its Regulation by Upf2 von Chakrabarti, Sutapa, Jayachandran, Uma, Bonneau, Fabien, Fiorini, Francesca, Basquin, Claire, Domcke, Silvia, Le Hir, Hervé, Conti, Elena

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Structure of the Exon Junction Core Complex with a Trapped DEAD-Box ATPase Bound to RNA von Andersen, Christian B.F, Ballut, Lionel, Johansen, Jesper S, Chamieh, Hala, Nielsen, Klaus H, Oliveira, Cristiano L.P, Pedersen, Jan Skov, Séraphin, Bertrand, Le Hir, Hervé, Andersen, Gregers Rom

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A role for AKT1 in nonsense-mediated mRNA decay von Palma, Martine, Leroy, Catherine, Salomé-Desnoulez, Sophie, Werkmeister, Elisabeth, Kong, Rebekah, Mongy, Marc, Le Hir, Hervé, Lejeune, Fabrice

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Exon Junction Complexes can have distinct functional flavours to regulate specific splicing events von Wang, Zhen, Ballut, Lionel, Barbosa, Isabelle, Le Hir, Hervé

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A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport von Safieddine, Adham, Coleno, Emeline, Salloum, Soha, Imbert, Arthur, Traboulsi, Abdel-Meneem, Kwon, Oh Sung, Lionneton, Frederic, Georget, Virginie, Robert, Marie-Cécile, Gostan, Thierry, Lecellier, Charles-Henri, Chouaib, Racha, Pichon, Xavier, Le Hir, Hervé, Zibara, Kazem, Mueller, Florian, Walter, Thomas, Peter, Marion, Bertrand, Edouard

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Exon-junction complex association with stalled ribosomes and slow translation-independent disassembly von Bensaude, Olivier, Barbosa, Isabelle, Morillo, Lucia, Dikstein, Rivka, Le Hir, Hervé

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Nonsense‐mediated mRNA decay involves two distinct Upf1‐bound complexes von Dehecq, Marine, Decourty, Laurence, Namane, Abdelkader, Proux, Caroline, Kanaan, Joanne, Le Hir, Hervé, Jacquier, Alain, Saveanu, Cosmin

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Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly von Barbosa, Isabelle, Haque, Nazmul, Fiorini, Francesca, Barrandon, Charlotte, Tomasetto, Catherine, Blanchette, Marco, Le Hir, Hervé

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NCBP3 positively impacts mRNA biogenesis von Dou, Yuhui, Barbosa, Isabelle, Jiang, Hua, Iasillo, Claudia, Molloy, Kelly R., Schulze, Wiebke Manuela, Cusack, Stephen, Schmid, Manfred, Le Hir, Herve, LaCava, John, Jensen, Torben Heick

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Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes von Busetto, Virginia, Barbosa, Isabelle, Basquin, Jerome, Marquenet, Emelie, Hocq, Remi, Hennion, Magali, Paternina, Janio Antonio, Namane, Abdelkader, Conti, Elena, Bensaude, Olivier, Le Hir, Herve

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NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity von Le Hir, Hervé, Ballut, Lionel, Chamieh, Hala, Bonneau, Fabien

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Monitored eCLIP: high accuracy mapping of RNA-protein interactions von Hocq, Rémi, Paternina, Janio, Alasseur, Quentin, Genovesio, Auguste, Le Hir, Hervé

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UPF1-like helicase grip on nucleic acids dictates processivity von Kanaan, Joanne, Raj, Saurabh, Decourty, Laurence, Saveanu, Cosmin, Croquette, Vincent, Le Hir, Hervé

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Insights into the design and interpretation of iCLIP experiments von Haberman, Nejc, Huppertz, Ina, Attig, Jan, König, Julian, Wang, Zhen, Hauer, Christian, Hentze, Matthias W, Kulozik, Andreas E, Le Hir, Hervé, Curk, Tomaž, Sibley, Christopher R, Zarnack, Kathi, Ule, Jernej

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The structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complex von Murachelli, Andrea Giovanni, Ebert, Judith, Basquin, Claire, Le Hir, Hervé, Conti, Elena

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A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner von Gowravaram, Manjeera, Bonneau, Fabien, Kanaan, Joanne, Maciej, Vincent D, Fiorini, Francesca, Raj, Saurabh, Croquette, Vincent, Le Hir, Hervé, Chakrabarti, Sutapa

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Comprehensive mapping of exon junction complex binding sites reveals universal EJC deposition in Drosophila von Morillo, Lucía, Paternina, Toni, Alasseur, Quentin, Genovesio, Auguste, Schwartz, Schraga, Le Hir, Hervé

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The exon junction complex as a node of post-transcriptional networks von Hir, Hervé Le, Saulière, Jérôme, Wang, Zhen

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Crystal structure of the human eIF4AIII–CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domain von Buchwald, Gretel, Schüssler, Steffen, Basquin, Claire, Le Hir, Hervé, Conti, Elena

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HTLV-1 Tax plugs and freezes UPF1 helicase leading to nonsense-mediated mRNA decay inhibition von Fiorini, Francesca, Robin, Jean-Philippe, Kanaan, Joanne, Borowiak, Malgorzata, Croquette, Vincent, Le Hir, Hervé, Jalinot, Pierre, Mocquet, Vincent

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