Preparation of neplanocin-A from D-ribose and by a chemoenzymic method von HILL, J. M, HUTCHINSON, E. J, LE GRAND, D. M, ROBERTS, S. M, THORPE, A. J, TURNER, N. J

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Enzyme-catalysed hydrolyses of some meso-diesters von COTTERILL, I. C, COX, P. B, SIK, V, WILLIAMS, J. O, DRAKE, A. F, LE GRAND, D. M, HUTCHINSON, E. J, LATOUCHE, R, PETTMAN, R. B, PRYCE, R. J, ROBERTS, S. M, RYBACK, G

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Carbocyclic adenosine phosphates as nucleotide mimics in some enzyme-catalysed reactions von LE GRAND, D. M, ROBERTS, S. M

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N-(4-aryloxypiperidin-1-ylalkyl) cinnamic amides as CCR33 receptor antagonists von Bhalay, Gurdip, Howe, Trevor J, Le Grand, Darren M

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DERIVADOS DE AZETIDINA 1,3-DISUSTITUIDA PARA SER UTILIZADOS COMO ANTAGONISTAS DEL RECEPTOR CCR EN EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS Y ALERGICAS von LE GRAND, DARREN M

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1,3-DISUBSTITUIERTE AZETIDINDERIVATE ZUR VERWENDUNG ALS ANTAGONISTEN DES CCR-3-REZEPTORS BEI DER BEHANDLUNG VON ENTZÜNDLICHEN UND ALLERGISCHEN KRANKHEITEN von LE GRAND, DARREN M

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1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES von LE, GRAND DARREN M

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1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES von DARREN M. LE GRAND

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1,3-DISUBSTITUIERTE AZETIDINDERIVATE ZUR VERWENDUNG ALS ANTAGONISTEN DES CCR-3-REZEPTORS BEI DER BEHANDLUNG VON ENTZÜNDLICHEN UND ALLERGISCHEN KRANKHEITEN von LE GRAND, DARREN M

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1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES von LE GRAND, DARREN M

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1,3 Disubstituted azetidine derivatives for use as ccr-3 receptor antagonists in the treatment of inflammatory and allergic diseases von LE GRAND DARREN M

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1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES von LE GRAND, DARREN M

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5-PHENYL-4-METHYL-THIAZOL-2-YL-AMINE DERIVATIVES AS INHIBITORS OF PHOSPHATIDYLINOSITOL 3 KINASE ENZYMES (PI3) FOR THE TREATMENT OF INFLAMMATORY AIRWAY DISEASES von G. C. BLOOMFIELD, JUDY FOX HAYLER, IAN BRUCE, CATHERINE LEBLANC, DARREN M. LE GRAND, CLIVE MCCARTHY

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Azetidine derivatives as CCR-3 receptor antagonists von WOODS, JOHN, J, WALKER, CLIVE, V, LE GRAND, DARREN, M, CLIVE MCCARTHY

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N-(4-aryloxypiperidin-1-ylalkyl) cinnamic amides as CCR33 receptor antagonists von LE GRAND DARREN M, HOWE TREVOR J, BHALAY GURDIP

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Azetidine derivatives as ccr-3 receptor antagonists von LE GRAND DARREN M, WOODS JOHN J, MCCARTHY CLIVE, WALKER CLIVE V

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Inhibitors of phosphatidylinositol 3-kinase von PILGRIM GAYNOR E, LE GRAND DARREN M, KELLER THOMAS H, VALADE BARBARA, BRUCE IAN, BUDD EMMA, PRESS NICOLA, HAYLER JUDY, CUENOUD BERNARD, RITCHIE CATHY

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A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct von Ocasio, Cory A, Rajasekaran, Mohan B, Walker, Sarah, Le Grand, Darren, Spencer, John, Pearl, Frances M G, Ward, Simon E, Savic, Velibor, Pearl, Laurence H, Hochegger, Helfrid, Oliver, Antony W

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The Discovery of orally available thrombin inhibitors : Studies towards the optimisation of CGH1668 von Ambler, John, Baker, Emma, Brown, Lyndon, Butler, Paul, Farr, Dave, Dunnet, Karen, Grand, Darren Le, Janus, Diana, Jones, Darryl, Menear, Keith, Mercer, Mark, Smith, Garrick, Talbot, Mark, Tweed, Morris

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The discovery of orally available thrombin inhibitors: Optimisation of the P1 pharmacophore von Ambler, John, Bentley, David, Brown, Lyndon, Dunnet, Karen, Farr, Dave, Janus, Diana, Grand, Darren Le, Menear, Keith, Mercer, Mark, Talbot, Mark, Tweed, Morris, Wathey, Bernard

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