Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus von Kirn, David H, Wang, Yaohe, Le Boeuf, Fabrice, Bell, John, Thorne, Steve H

Volltext

Endothelial Cell Migration During Angiogenesis von Lamalice, Laurent, Le Boeuf, Fabrice, Huot, Jacques

Volltext

A High-throughput Pharmacoviral Approach Identifies Novel Oncolytic Virus Sensitizers von Diallo, Jean-Simon, Boeuf, Fabrice Le, Lai, Frances, Cox, Julie, Vaha-Koskela, Markus, Abdelbary, Hesham, MacTavish, Heather, Waite, Katherine, Falls, Theresa, Wang, Jenny, Brown, Ryan, Blanchard, Jan E, Brown, Eric D, Kirn, David H, Hiscott, John, Atkins, Harry, Lichty, Brian D, Bell, John C

Volltext

Oncolytic viruses sensitize human tumor cells for NY-ESO-1 tumor antigen recognition by CD4+ effector T cells von Delaunay, Tiphaine, Violland, Mathilde, Boisgerault, Nicolas, Dutoit, Soizic, Vignard, Virginie, Münz, Christian, Gannage, Monique, Dréno, Brigitte, Vaivode, Kristine, Pjanova, Dace, Labarrière, Nathalie, Wang, Yaohe, Chiocca, E. Antonio, Boeuf, Fabrice Le, Bell, John C., Erbs, Philippe, Tangy, Frédéric, Grégoire, Marc, Fonteneau, Jean-François

Volltext

Antiangiogenic Arming of an Oncolytic Vaccinia Virus Enhances Antitumor Efficacy in Renal Cell Cancer Models von Guse, Kilian, Sloniecka, Marta, Diaconu, Iulia, Ottolino-Perry, Kathryn, Tang, Nan, Ng, Calvin, Le Boeuf, Fabrice, Bell, John C, McCart, J Andrea, Ristimäki, Ari, Pesonen, Sari, Cerullo, Vincenzo, Hemminki, Akseli

Volltext

Resistance to Two Heterologous Neurotropic Oncolytic Viruses, Semliki Forest Virus and Vaccinia Virus, in Experimental Glioma von Vähä-Koskela, Markus J V, Le Boeuf, Fabrice, Lemay, Chantal, De Silva, Naomi, Diallo, Jean-Simon, Cox, Julie, Becker, Michelle, Choi, Youngmin, Ananth, Abhirami, Sellers, Clara, Breton, Sophie, Roy, Dominic, Falls, Theresa, Brun, Jan, Hemminki, Akseli, Hinkkanen, Ari, Bell, John C

Volltext

Multi-modal Potentiation of Oncolytic Virotherapy by Vanadium Compounds von Selman, Mohammed, Rousso, Christopher, Bergeron, Anabel, Son, Hwan Hee, Krishnan, Ramya, El-Sayes, Nader A., Varette, Oliver, Chen, Andrew, Le Boeuf, Fabrice, Tzelepis, Fanny, Bell, John C., Crans, Debbie C., Diallo, Jean-Simon

Volltext

Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity von Ilkow, Carolina S, Marguerie, Monique, Batenchuk, Cory, Mayer, Justin, Ben Neriah, Daniela, Cousineau, Sophie, Falls, Theresa, Jennings, Victoria A, Boileau, Meaghan, Bellamy, David, Bastin, Donald, de Souza, Christiano Tanese, Alkayyal, Almohanad, Zhang, Jiqing, Le Boeuf, Fabrice, Arulanandam, Rozanne, Stubbert, Lawton, Sampath, Padma, Thorne, Steve H, Paramanthan, Piriya, Chatterjee, Avijit, Strieter, Robert M, Burdick, Marie, Addison, Christina L, Stojdl, David F, Atkins, Harold L, Auer, Rebecca C, Diallo, Jean-Simon, Lichty, Brian D, Bell, John C

Volltext

The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers von Parato, Kelley A, Breitbach, Caroline J, Le Boeuf, Fabrice, Wang, Jiahu, Storbeck, Chris, Ilkow, Carolina, Diallo, Jean-Simon, Falls, Theresa, Burns, Joseph, Garcia, Vanessa, Kanji, Femina, Evgin, Laura, Hu, Kang, Paradis, Francois, Knowles, Shane, Hwang, Tae-Ho, Vanderhyden, Barbara C, Auer, Rebecca, Kirn, David H, Bell, John C

Volltext

Smac mimetics and innate immune stimuli synergize to promote tumor death von Beug, Shawn T, Tang, Vera A, LaCasse, Eric C, Cheung, Herman H, Beauregard, Caroline E, Brun, Jan, Nuyens, Jeffrey P, Earl, Nathalie, St-Jean, Martine, Holbrook, Janelle, Dastidar, Himika, Mahoney, Douglas J, Ilkow, Carolina, Le Boeuf, Fabrice, Bell, John C, Korneluk, Robert G

Volltext

Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors von Pol, Jonathan G., Lévesque, Sarah, Workenhe, Samuel T., Gujar, Shashi, Le Boeuf, Fabrice, Clements, Derek R., Fahrner, Jean-Eudes, Fend, Laetitia, Bell, John C., Mossman, Karen L., Fucikova, Jitka, Spisek, Radek, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo

Volltext

Oncolytic Maraba Virus MG1 as a Treatment for Sarcoma von Le Boeuf, Fabrice, Selman, Mohammed, Son, Hwan Hee, Bergeron, Anabel, Chen, Andrew, Tsang, Jovian, Butterwick, Derek, Arulanandam, Rozanne, Forbes, Nicole E., Tzelepis, Fanny, Bell, John C., Werier, Joel, Abdelbary, Hesham, Diallo, Jean‐Simon

Volltext

Viral Delivery of CAR Targets to Solid Tumors Enables Effective Cell Therapy von Aalipour, Amin, Le Boeuf, Fabrice, Tang, Matthew, Murty, Surya, Simonetta, Federico, Lozano, Alexander X., Shaffer, Travis M., Bell, John C., Gambhir, Sanjiv S.

Volltext

Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis von Zakaria, Chadi, Sean, Polen, Hoang, Huy-Dung, Leroux, Louis-Phillipe, Watson, Margaret, Workenhe, Samuel Tekeste, Hearnden, Jaclyn, Pearl, Dana, Truong, Vinh Tai, Robichaud, Nathaniel, Yanagiya, Akiko, Tahmasebi, Soroush, Jafarnejad, Seyed Mehdi, Jia, Jian-Jun, Pelin, Adrian, Diallo, Jean-Simon, Le Boeuf, Fabrice, Bell, John Cameron, Mossman, Karen Louise, Graber, Tyson Ernst, Jaramillo, Maritza, Sonenberg, Nahum, Alain, Tommy

Volltext

Regulation of Vascular Endothelial Growth Factor Receptor 2-mediated Phosphorylation of Focal Adhesion Kinase by Heat Shock Protein 90 and Src Kinase Activities von Le Boeuf, Fabrice, Houle, François, Huot, Jacques

Volltext

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans von Breitbach, Caroline J., Burke, James, Jonker, Derek, Stephenson, Joe, Haas, Andrew R., Chow, Laura Q. M., Nieva, Jorge, Hwang, Tae-Ho, Moon, Anne, Patt, Richard, Pelusio, Adina, Le Boeuf, Fabrice, Burns, Joe, Evgin, Laura, De Silva, Naomi, Cvancic, Sara, Robertson, Terri, Je, Ji-Eun, Lee, Yeon-Sook, Parato, Kelley, Diallo, Jean-Simon, Fenster, Aaron, Daneshmand, Manijeh, Bell, John C., Kirn, David H.

Volltext

Sensitivity of cervical carcinoma cells to vesicular stomatitis virus-induced oncolysis: Potential role of human papilloma virus infection von Le Boeuf, Fabrice, Niknejad, Nima, Wang, Jiahu, Auer, Rebecca, Weberpals, Johanne I., Bell, John C., Dimitroulakos, Jim

Volltext

The importance of imaging strategies for pre-clinical and clinical in vivo distribution of oncolytic viruses von Pelin, Adrian, Wang, Jiahu, Bell, John, Le Boeuf, Fabrice

Volltext

Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors von MacTavish, Heather, Diallo, Jean-Simon, Huang, Baocheng, Stanford, Marianne, Le Boeuf, Fabrice, De Silva, Naomi, Cox, Julie, Simmons, John Graydon, Guimond, Tanya, Falls, Theresa, McCart, J Andrea, Atkins, Harry, Breitbach, Caroline, Kirn, David, Thorne, Stephen, Bell, John C

Volltext

Deletion of Apoptosis Inhibitor F1L in Vaccinia Virus Increases Safety and Oncolysis for Cancer Therapy von Pelin, Adrian, Foloppe, Johann, Petryk, Julia, Singaravelu, Ragunath, Hussein, Marian, Gossart, Florian, Jennings, Victoria A., Stubbert, Lawton J., Foster, Madison, Storbeck, Christopher, Postigo, Antonio, Scut, Elena, Laight, Brian, Way, Michael, Erbs, Philippe, Le Boeuf, Fabrice, Bell, John C.

Volltext