Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials von Schwaederle, Maria, Zhao, Melissa, Lee, J Jack, Eggermont, Alexander M, Schilsky, Richard L, Mendelsohn, John, Lazar, Vladimir, Kurzrock, Razelle

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Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial von Rodon, Jordi, Soria, Jean-Charles, Berger, Raanan, Miller, Wilson H., Rubin, Eitan, Kugel, Aleksandra, Tsimberidou, Apostolia, Saintigny, Pierre, Ackerstein, Aliza, Braña, Irene, Loriot, Yohann, Afshar, Mohammad, Miller, Vincent, Wunder, Fanny, Bresson, Catherine, Martini, Jean-François, Raynaud, Jacques, Mendelsohn, John, Batist, Gerald, Onn, Amir, Tabernero, Josep, Schilsky, Richard L., Lazar, Vladimir, Lee, J. Jack, Kurzrock, Razelle

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High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial von Massard, Christophe, Michiels, Stefan, Ferté, Charles, Le Deley, Marie-Cécile, Lacroix, Ludovic, Hollebecque, Antoine, Verlingue, Loic, Ileana, Ecaterina, Rosellini, Silvia, Ammari, Samy, Ngo-Camus, Maud, Bahleda, Rastislav, Gazzah, Anas, Varga, Andrea, Postel-Vinay, Sophie, Loriot, Yohann, Even, Caroline, Breuskin, Ingrid, Auger, Nathalie, Job, Bastien, De Baere, Thierry, Deschamps, Frederic, Vielh, Philippe, Scoazec, Jean-Yves, Lazar, Vladimir, Richon, Catherine, Ribrag, Vincent, Deutsch, Eric, Angevin, Eric, Vassal, Gilles, Eggermont, Alexander, André, Fabrice, Soria, Jean-Charles

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Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-analysis of Clinical Trials Leading to FDA Approval von Jardim, Denis L, Fontes Jardim, Denis L, Schwaederle, Maria, Wei, Caimiao, Lee, J Jack, Hong, David S, Eggermont, Alexander M, Schilsky, Richard L, Mendelsohn, John, Lazar, Vladimir, Kurzrock, Razelle

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An Immunosurveillance Mechanism Controls Cancer Cell Ploidy von Senovilla, Laura, Vitale, Ilio, Martins, Isabelle, Tailler, Maximilien, Pailleret, Claire, Michaud, Mickaël, Galluzzi, Lorenzo, Adjemian, Sandy, Kepp, Oliver, Niso-Santano, Mireia, Shen, Shensi, Mariño, Guillermo, Criollo, Alfredo, Boilève, Alice, Job, Bastien, Ladoire, Sylvain, Ghiringhelli, François, Sistigu, Antonella, Yamazaki, Takahiro, Rello-Varona, Santiago, Locher, Clara, Poirier-Colame, Vichnou, Talbot, Monique, Valent, Alexander, Berardinelli, Francesco, Antoccia, Antonio, Ciccosanti, Fabiola, Fimia, Gian Maria, Piacentini, Mauro, Fueyo, Antonio, Messina, Nicole L., Li, Ming, Chan, Christopher J., Sigl, Verena, Pourcher, Guillaume, Ruckenstuhl, Christoph, Carmona-Gutierrez, Didac, Lazar, Vladimir, Penninger, Josef M., Madeo, Frank, López-Otín, Carlos, Smyth, Mark J., Zitvogel, Laurence, Castedo, Maria, Kroemer, Guido

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SERS-based differential diagnosis between multiple solid malignancies: breast, colorectal, lung, ovarian and oral cancer von Moisoiu, Vlad, Stefancu, Andrei, Gulei, Diana, Boitor, Radu, Magdo, Lorand, Raduly, Lajos, Pasca, Sergiu, Kubelac, Paul, Mehterov, Nikolay, Chiș, Vasile, Simon, Marioara, Muresan, Mihai, Irimie, Alexandra Iulia, Baciut, Mihaela, Stiufiuc, Rares, Pavel, Ioana E, Achimas-Cadariu, Patriciu, Ionescu, Calin, Lazar, Vladimir, Sarafian, Victoria, Notingher, Ioan, Leopold, Nicolae, Berindan-Neagoe, Ioana

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miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death von GALLUZZI, Lorenzo, MORSELLI, Eugenia, RIPOCHE, Hugues, LAZAR, Vladimir, HAREL-BELLAN, Annick, DESSEN, Philippe, BARILLOT, Emmanuel, KROEMER, Guido, VITALE, Ilio, KEPP, Oliver, SENOVILLA, Laura, CRIOLLO, Alfredo, SERVANT, Nicolas, PACCARD, Caroline, HUPE, Philippe, ROBERT, Thomas

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Network enrichment analysis: extension of gene-set enrichment analysis to gene networks von Alexeyenko, Andrey, Lee, Woojoo, Pernemalm, Maria, Guegan, Justin, Dessen, Philippe, Lazar, Vladimir, Lehtiö, Janne, Pawitan, Yudi

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Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas von Puget, Stephanie, Philippe, Cathy, Bax, Dorine A, Job, Bastien, Varlet, Pascale, Junier, Marie-Pierre, Andreiuolo, Felipe, Carvalho, Dina, Reis, Ricardo, Guerrini-Rousseau, Lea, Roujeau, Thomas, Dessen, Philippe, Richon, Catherine, Lazar, Vladimir, Le Teuff, Gwenael, Sainte-Rose, Christian, Geoerger, Birgit, Vassal, Gilles, Jones, Chris, Grill, Jacques

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Next-Generation Sequencing Reveals High Concordance of Recurrent Somatic Alterations Between Primary Tumor and Metastases From Patients With Non–Small-Cell Lung Cancer von VIGNOT, Stéphane, FRAMPTON, Garrett M, ANDRE, Fabrice, STEPHENS, Philip J, LAZAR, Vladimir, MILLER, Vincent A, BRAMBILLA, Elisabeth, SORIA, Jean-Charles, YELENSKY, Roman, COMMO, Frédéric, BRAMBILLA, Christian, PALMER, Gary, MORO-SIBILOT, Denis, ROSS, Jeffrey S, CRONIN, Maureen T

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Molecular Characterization of Breast Cancer with High-Resolution Oligonucleotide Comparative Genomic Hybridization Array von ANDRE, Fabrice, JOB, Bastien, DELALOGE, Suzette, HORTOBAGYI, Gabriel N, SYMMANS, W. Fraser, LAZAR, Vladimir, PUSZTAI, Lajos, DESSEN, Philippe, TORDAI, Attila, MICHIELS, Stefan, LIEDTKE, Cornelia, RICHON, Catherine, KAI YAN, BAILANG WANG, VASSAL, Gilles

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Targeting the Deregulated Spliceosome Core Machinery in Cancer Cells Triggers mTOR Blockade and Autophagy von QUIDVILLE, Virginie, ALSAFADI, Samar, DELALOGE, Suzette, SAGHATCHIAN, Mahasti, PAUTIER, Patricia, MORICE, Philippe, DESSEN, Philippe, VAGNER, Stephan, ANDRE, Fabrice, GOUBAR, Aïcha, COMMO, Frédéric, SCOTT, Véronique, PIOCHE-DURIEU, Catherine, GIRAULT, Isabelle, BACONNAIS, Sonia, LE CAM, Eric, LAZAR, Vladimir

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Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome von Winnepenninckx, Véronique, Lazar, Vladimir, Michiels, Stefan, Dessen, Philippe, Stas, Marguerite, Alonso, Soledad R., Avril, Marie-Françoise, Ortiz Romero, Pablo L., Robert, Thomas, Balacescu, Ovidiu, Eggermont, Alexander M. M., Lenoir, Gilbert, Sarasin, Alain, Tursz, Thomas, van den Oord, Joost J., Spatz, Alain

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Adipocyte-Based Cell Therapy in Oncology: The Role of Cancer-Associated Adipocytes and Their Reinterpretation as Delivery Platforms von Munteanu, Raluca, Onaciu, Anca, Moldovan, Cristian, Zimta, Alina-Andreea, Gulei, Diana, Paradiso, Angelo V, Lazar, Vladimir, Berindan-Neagoe, Ioana

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Survey of Human Genes of Retroviral Origin: Identification and Transcriptome of the Genes with Coding Capacity for Complete Envelope Proteins von de Parseval, Nathalie, Lazar, Vladimir, Casella, Jean-François, Benit, Laurence, Heidmann, Thierry

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Tumor Tissue Explant Culture of Patient-Derived Xenograft as Potential Prioritization Tool for Targeted Therapy von Ghosh, Susmita, Prasad, Manu, Kundu, Kiran, Cohen, Limor, Yegodayev, Ksenia M, Zorea, Jonathan, Joshua, Ben-Zion, Lasry, Batel, Dimitstein, Orr, Bahat-Dinur, Anat, Mizrachi, Aviram, Lazar, Vladimir, Elkabets, Moshe, Porgador, Angel

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A WIN Consortium phase I study exploring avelumab, palbociclib, and axitinib in advanced non‐small cell lung cancer von Solomon, Benjamin, Callejo, Ana, Bar, Jair, Berchem, Guy, Bazhenova, Lyudmila, Saintigny, Pierre, Wunder, Fanny, Raynaud, Jacques, Girard, Nicolas, Lee, J. Jack, Sulaiman, Raed, Prouse, Bruce, Bresson, Catherine, Ventura, Hila, Magidi, Shai, Rubin, Eitan, Young, Brandon, Onn, Amir, Leyland‐Jones, Brian, Schilsky, Richard L., Lazar, Vladimir, Felip, Enriqueta, Kurzrock, Razelle

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Identification of a central network hub of key prognostic genes based on correlation between transcriptomics and survival in patients with metastatic solid tumors von Lazar, Vladimir, Raymond, Eric, Magidi, Shai, Bresson, Catherine, Wunder, Fanny, Berindan-Neagoe, Ioana, Tijeras-Rabaland, Annemilaï, Raynaud, Jacques, Onn, Amir, Ducreux, Michel, Batist, Gerald, Lassen, Ulrik, Cilius Nielsen, Fin, Schilsky, Richard L., Rubin, Eitan, Kurzrock, Razelle

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Chk1 as a new therapeutic target in triple-negative breast cancer von Albiges, Laurence, Goubar, Aïcha, Scott, Véronique, Vicier, Cécile, Lefèbvre, Céline, Alsafadi, Samar, Commo, Frédéric, Saghatchian, Mahasti, Lazar, Vladimir, Dessen, Philippe, Delaloge, Suzette, André, Fabrice, Quidville, Virginie

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A transcriptomics approach to expand therapeutic options and optimize clinical trials in oncology von Lazar, Vladimir, Zhang, Baolin, Magidi, Shai, Le Tourneau, Christophe, Raymond, Eric, Ducreux, Michel, Bresson, Catherine, Raynaud, Jacques, Wunder, Fanny, Onn, Amir, Felip, Enriqueta, Tabernero, Josep, Batist, Gerald, Kurzrock, Razelle, Rubin, Eitan, Schilsky, Richard L.

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