Recent advances in understanding the molecular basis of Paget disease of bone von Goode, A, Layfield, R

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5‐HT6 receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms von Woods, S, Clarke, NN, Layfield, R, Fone, KCF

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Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle von Greenhaff, P. L, Karagounis, L. G, Peirce, N, Simpson, E. J, Hazell, M, Layfield, R, Wackerhage, H, Smith, K, Atherton, P, Selby, A, Rennie, M. J

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p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death von Foster, A. D., Flynn, L. L., Cluning, C., Cheng, F., Davidson, J. M., Lee, A., Polain, N., Mejzini, R., Farrawell, N., Yerbury, J. J., Layfield, R., Akkari, P. A., Rea, S. L.

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Ubiquitin and NF-κB signalling in Paget's disease von Layfield, R

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An FTLD-associated SQSTM1 variant impacts Nrf2 and NF-κB signalling and is associated with reduced phosphorylation of p62 von Foster, A., Scott, D., Layfield, R., Rea, S.L.

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The 'dark matter' of ubiquitin-mediated processes: opportunities and challenges in the identification of ubiquitin-binding domains von Radley, E H, Long, J, Gough, K C, Layfield, R

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ALS-associated TBK1 variant p.G175S is defective in phosphorylation of p62 and impacts TBK1-mediated signalling and TDP-43 autophagic degradation von Foster, A.D., Downing, P., Figredo, E., Polain, N., Stott, A., Layfield, R., Rea, S.L.

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Temporal changes in the involvement of pyruvate dehydrogenase complex in muscle lactate accumulation during lipopolysaccharide infusion in rats von Alamdari, N, Constantin-Teodosiu, D, Murton, A J, Gardiner, S M, Bennett, T, Layfield, R, Greenhaff, P L

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Review: unchained maladie - a reassessment of the role of Ubb(+1) -capped polyubiquitin chains in Alzheimer's disease von Chadwick, L, Gentle, L, Strachan, J, Layfield, R

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Proteomic biomarkers for the diagnosis and risk stratification of polycystic ovary syndrome: a systematic review von Atiomo, W, Khalid, S, Parameshweran, S, Houda, M, Layfield, R

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Review: The ubiquitin-proteasome system: contributions to cell death or survival in neurodegeneration von Rogers, N, Paine, S, Bedford, L, Layfield, R

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Review: The ubiquitin-proteasome system: contributions to cell death or survival in neurodegeneration von Rogers, N., Paine, S., Bedford, L., Layfield, R.

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Second-harmonic generation imaging of collagen in ancient bone von Thomas, B, McIntosh, D, Fildes, T, Smith, L, Hargrave, F, Islam, M, Thompson, T, Layfield, R, Scott, D, Shaw, B, Burrell, C L, Gonzalez, S, Taylor, S

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Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone von Cavey, J R, Ralston, S H, Sheppard, P W, Ciani, B, Gallagher, T R A, Long, J E, Searle, M S, Layfield, R

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SQSTM1 and Paget's disease of bone von Layfield, R, Hocking, L J

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Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline von Ralston, Stuart H, Corral‐Gudino, Luis, Cooper, Cyrus, Francis, Roger M, Fraser, William D, Gennari, Luigi, Guañabens, Núria, Javaid, M Kassim, Layfield, Robert, O'Neill, Terence W, Russell, R Graham G, Stone, Michael D, Simpson, Keith, Wilkinson, Diana, Wills, Ruth, Zillikens, M Carola, Tuck, Stephen P

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Review: Unchained maladie - a reassessment of the role of Ubb+1-capped polyubiquitin chains in Alzheimer's disease von Chadwick, L., Gentle, L., Strachan, J., Layfield, R.

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Functional and structural studies of two UBA domain missense mutations of sequestosome 1 (SQSTM1) in Paget's disease of bone von Goode, A.J, Long, J, Shaw, B, Williams, H, Ralston, S, Searle, M, Layfield, R

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Nuclear inclusions and dysregulated autophagy in osteoclasts in a mouse model of Paget's disease of bone caused by P394L SQSTM1 mutation von Daroszewska, A, van't Hof, R, Landao-Basonga, E, Layfield, R, Rose, L, Ralston, S

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