ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer von Mahajan, Kiran, Malla, Pavani, Lawrence, Harshani R., Chen, Zhihua, Kumar-Sinha, Chandan, Malik, Rohit, Shukla, Sudhanshu, Kim, Jongphil, Coppola, Domenico, Lawrence, Nicholas J., Mahajan, Nupam P.

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Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer von McGuire, Jeremy J., Frieling, Jeremy S., Lo, Chen Hao, Li, Tao, Muhammad, Ayaz, Lawrence, Harshani R., Lawrence, Nicholas J., Cook, Leah M., Lynch, Conor C.

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A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation von XIAOLEI ZHANG, YING SUN, PIREDDU, Roberta, HUA YANG, URLAM, Murali K, LAWRENCE, Harshani R, GUIDA, Wayne C, LAWRENCE, Nicholas J, SEBTI, Saïd M

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Structural Insights into JAK2 Inhibition by Ruxolitinib, Fedratinib, and Derivatives Thereof von Davis, Ryan R, Li, Baoli, Yun, Sang Y, Chan, Alice, Nareddy, Pradeep, Gunawan, Steven, Ayaz, Muhammad, Lawrence, Harshani R, Reuther, Gary W, Lawrence, Nicholas J, Schönbrunn, Ernst

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Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity von Siddiquee, Khandaker, Zhang, Shumin, Guida, Wayne C, Blaskovich, Michelle A, Greedy, Benjamin, Lawrence, Harshani R, Yip, M.L. Richard, Jove, Richard, McLaughlin, Mark M, Lawrence, Nicholas J, Sebti, Said M, Turkson, James

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Rural Water Point Functionality Estimates and Associations: Evidence From Nine Countries in Sub‐Saharan Africa and South Asia von Murray, Anna L., Stone, Gabriela, Yang, Audrey R., Lawrence, Nicholas F., Matthews, Hannah, Kayser, Georgia L.

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ACK1 Tyrosine Kinase Interacts with Histone Demethylase KDM3A to Regulate the Mammary Tumor Oncogene HOXA1 von Mahajan, Kiran, Lawrence, Harshani R., Lawrence, Nicholas J., Mahajan, Nupam P.

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Development of SOS1 Inhibitor-Based Degraders to Target KRAS-Mutant Colorectal Cancer von Bian, Yujia, Alem, Diego, Beato, Francisca, Hogenson, Tara L., Yang, Xinrui, Jiang, Kun, Cai, Jianfeng, Ma, Wen Wee, Fernandez-Zapico, Martin, Tan, Aik Choon, Lawrence, Nicholas J., Fleming, Jason B., Yuan, Yu, Xie, Hao

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Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors von Karim, Rezaul Md, Bikowitz, Melissa J, Chan, Alice, Zhu, Jin-Yi, Grassie, Dylan, Becker, Andreas, Berndt, Norbert, Gunawan, Steven, Lawrence, Nicholas J, Schönbrunn, Ernst

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Ack1-mediated Androgen Receptor Phosphorylation Modulates Radiation Resistance in Castration-resistant Prostate Cancer von Mahajan, Kiran, Coppola, Domenico, Rawal, Bhupendra, Chen, Y. Ann, Lawrence, Harshani R., Engelman, Robert W., Lawrence, Nicholas J., Mahajan, Nupam P.

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Blockade of ACK1/TNK2 To Squelch the Survival of Prostate Cancer Stem-like Cells von Mahajan, Nupam P., Coppola, Domenico, Kim, Jongphil, Lawrence, Harshani R., Lawrence, Nicholas J., Mahajan, Kiran

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Regulation of Matrix Metalloproteinase Genes by E2F Transcription Factors: Rb-Raf-1 Interaction as a Novel Target for Metastatic Disease von JOHNSON, Jackie L, PILLAI, Smitha, PERNAZZA, Danielle, SEBTI, Saïd M, LAWRENCE, Nicholas J, CHELLAPPAN, Srikumar P

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Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor von Chen, Liwei, Sung, Shen-Shu, Yip, M L Richard, Lawrence, Harshani R, Ren, Yuan, Guida, Wayne C, Sebti, Said M, Lawrence, Nicholas J, Wu, Jie

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RKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast Cancer von PATEL, Ronil A, FORINASH, Kara D, PIREDDU, Roberta, YING SUN, NAN SUN, MARTIN, Mathew P, SCHÖNBRUNN, Ernst, LAWRENCE, Nicholas J, SEBTI, Saïd M

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Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon von Akuffo, Afua A., Alontaga, Aileen Y., Metcalf, Rainer, Beatty, Matthew S., Becker, Andreas, McDaniel, Jessica M., Hesterberg, Rebecca S., Goodheart, William E., Gunawan, Steven, Ayaz, Muhammad, Yang, Yan, Karim, Md Rezaul, Orobello, Morgan E., Daniel, Kenyon, Guida, Wayne, Yoder, Jeffrey A., Rajadhyaksha, Anjali M., Schönbrunn, Ernst, Lawrence, Harshani R., Lawrence, Nicholas J., Epling-Burnette, Pearlie K.

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Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: Synthesis and biological evaluation of antivascular activity von Ducki, Sylvie, Rennison, David, Woo, Meiko, Kendall, Alexander, Chabert, Jérémie Fournier Dit, McGown, Alan T., Lawrence, Nicholas J.

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Planar slot antenna with circular and vertical polarization diversity von Lawrence, Nicholas P., Fumeaux, Christophe, Abbott, Derek

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Pacritinib Combined with Sirolimus and Low-Dose Tacrolimus for GVHD Prevention after Allogeneic Hematopoietic Cell Transplantation: Preclinical and Phase I Trial Results von Pidala, Joseph, Walton, Kelly, Elmariah, Hany, Kim, Jongphil, Mishra, Asmita, Bejanyan, Nelli, Nishihori, Taiga, Khimani, Farhad, Perez, Lia, Faramand, Rawan G., Davila, Marco L., Nieder, Michael L., Sagatys, Elizabeth M., Holtan, Shernan G., Lawrence, Nicholas J., Lawrence, Harshani R., Blazar, Bruce R., Anasetti, Claudio, Sebti, Said M., Betts, Brian C.

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Planar Triorthogonal Diversity Slot Antenna von Lawrence, Nicholas P., Fumeaux, Christophe, Abbott, Derek

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Potent Dual BET Bromodomain-Kinase Inhibitors as Value-Added Multitargeted Chemical Probes and Cancer Therapeutics von Ember, Stuart W, Lambert, Que T, Berndt, Norbert, Gunawan, Steven, Ayaz, Muhammad, Tauro, Marilena, Zhu, Jin-Yi, Cranfill, Paula J, Greninger, Patricia, Lynch, Conor C, Benes, Cyril H, Lawrence, Harshani R, Reuther, Gary W, Lawrence, Nicholas J, Schönbrunn, Ernst

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