Cell-of-origin chromatin organization shapes the mutational landscape of cancer von Polak, Paz, Karlić, Rosa, Koren, Amnon, Thurman, Robert, Sandstrom, Richard, Lawrence, Michael S., Reynolds, Alex, Rynes, Eric, Vlahoviček, Kristian, Stamatoyannopoulos, John A., Sunyaev, Shamil R.

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A molecular mechanism for bacterial susceptibility to zinc von McDevitt, Christopher A, Ogunniyi, Abiodun D, Valkov, Eugene, Lawrence, Michael C, Kobe, Bostjan, McEwan, Alastair G, Paton, James C

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Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair von Haradhvala, Nicholas J., Polak, Paz, Stojanov, Petar, Covington, Kyle R., Shinbrot, Eve, Hess, Julian M., Rheinbay, Esther, Kim, Jaegil, Maruvka, Yosef E., Braunstein, Lior Z., Kamburov, Atanas, Hanawalt, Philip C., Wheeler, David A., Koren, Amnon, Lawrence, Michael S., Getz, Gad

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MET Alterations Are a Recurring and Actionable Resistance Mechanism in ALK-Positive Lung Cancer von Dagogo-Jack, Ibiayi, Yoda, Satoshi, Lennerz, Jochen K., Langenbucher, Adam, Lin, Jessica J., Rooney, Marguerite M., Prutisto-Chang, Kylie, Oh, Audris, Adams, Nathaniel A., Yeap, Beow Y., Chin, Emily, Do, Andrew, Marble, Hetal D., Stevens, Sara E., Digumarthy, Subba R., Saxena, Ashish, Nagy, Rebecca J., Benes, Cyril H., Azzoli, Christopher G., Lawrence, Michael S., Gainor, Justin F., Shaw, Alice T., Hata, Aaron N.

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Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain von Croll, Tristan I., Smith, Brian J., Margetts, Mai B., Whittaker, Jonathan, Weiss, Michael A., Ward, Colin W., Lawrence, Michael C.

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plyranges: a grammar of genomic data transformation von Lee, Stuart, Cook, Dianne, Lawrence, Michael

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Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy von Lohr, Jens G., Stojanov, Petar, Carter, Scott L., Cruz-Gordillo, Peter, Lawrence, Michael S., Auclair, Daniel, Sougnez, Carrie, Knoechel, Birgit, Gould, Joshua, Saksena, Gordon, Cibulskis, Kristian, McKenna, Aaron, Chapman, Michael A., Straussman, Ravid, Levy, Joan, Perkins, Louise M., Keats, Jonathan J., Schumacher, Steven E., Rosenberg, Mara, Anderson, Kenneth C., Richardson, Paul, Krishnan, Amrita, Lonial, Sagar, Kaufman, Jonathan, Siegel, David S., Vesole, David H., Roy, Vivek, Rivera, Candido E., Rajkumar, S. Vincent, Kumar, Shaji, Fonseca, Rafael, Ahmann, Greg J., Bergsagel, P. Leif, Stewart, A. Keith, Hofmeister, Craig C., Efebera, Yvonne A., Jagannath, Sundar, Chari, Ajai, Trudel, Suzanne, Reece, Donna, Wolf, Jeffrey, Martin, Thomas, Zimmerman, Todd, Rosenbaum, Cara, Jakubowiak, Andrzej J., Lebovic, Daniel, Vij, Ravi, Stockerl-Goldstein, Keith, Getz, Gad, Golub, Todd R.

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Sampling for Pharmaceuticals and Personal Care Products (PPCPs) and Illicit Drugs in Wastewater Systems: Are Your Conclusions Valid? A Critical Review von Ort, Christoph, Lawrence, Michael G, Rieckermann, Jörg, Joss, Adriano

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Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer von Ligorio, Matteo, Sil, Srinjoy, Malagon-Lopez, Jose, Nieman, Linda T., Misale, Sandra, Di Pilato, Mauro, Ebright, Richard Y., Karabacak, Murat N., Kulkarni, Anupriya S., Liu, Ann, Vincent Jordan, Nicole, Franses, Joseph W., Philipp, Julia, Kreuzer, Johannes, Desai, Niyati, Arora, Kshitij S., Rajurkar, Mihir, Horwitz, Elad, Neyaz, Azfar, Tai, Eric, Magnus, Neelima K.C., Vo, Kevin D., Yashaswini, Chittampalli N., Marangoni, Francesco, Boukhali, Myriam, Fatherree, Jackson P., Damon, Leah J., Xega, Kristina, Desai, Rushil, Choz, Melissa, Bersani, Francesca, Langenbucher, Adam, Thapar, Vishal, Morris, Robert, Wellner, Ulrich F., Schilling, Oliver, Lawrence, Michael S., Liss, Andrew S., Rivera, Miguel N., Deshpande, Vikram, Benes, Cyril H., Maheswaran, Shyamala, Haber, Daniel A., Fernandez-Del-Castillo, Carlos, Ferrone, Cristina R., Haas, Wilhelm, Aryee, Martin J., Ting, David T.

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Oncotator: Cancer Variant Annotation Tool von Ramos, Alex H., Lichtenstein, Lee, Gupta, Manaswi, Lawrence, Michael S., Pugh, Trevor J., Saksena, Gordon, Meyerson, Matthew, Getz, Gad

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Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes von Leiserson, Mark D M, Vandin, Fabio, Wu, Hsin-Ta, Dobson, Jason R, Eldridge, Jonathan V, Thomas, Jacob L, Papoutsaki, Alexandra, Kim, Younhun, Niu, Beifang, McLellan, Michael, Lawrence, Michael S, Gonzalez-Perez, Abel, Tamborero, David, Cheng, Yuwei, Ryslik, Gregory A, Lopez-Bigas, Nuria, Getz, Gad, Ding, Li, Raphael, Benjamin J

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Sampling for PPCPs in Wastewater Systems: Comparison of Different Sampling Modes and Optimization Strategies von Ort, Christoph, Lawrence, Michael G, Reungoat, Julien, Mueller, Jochen F

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Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing von Helman, Elena, Lawrence, Michael S, Stewart, Chip, Sougnez, Carrie, Getz, Gad, Meyerson, Matthew

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Punctuated Evolution of Prostate Cancer Genomes von Baca, Sylvan C., Prandi, Davide, Lawrence, Michael S., Mosquera, Juan Miguel, Romanel, Alessandro, Drier, Yotam, Park, Kyung, Kitabayashi, Naoki, MacDonald, Theresa Y., Ghandi, Mahmoud, Van Allen, Eliezer, Kryukov, Gregory V., Sboner, Andrea, Theurillat, Jean-Philippe, Soong, T. David, Nickerson, Elizabeth, Auclair, Daniel, Tewari, Ashutosh, Beltran, Himisha, Onofrio, Robert C., Boysen, Gunther, Guiducci, Candace, Barbieri, Christopher E., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Saksena, Gordon, Voet, Douglas, Ramos, Alex H., Winckler, Wendy, Cipicchio, Michelle, Ardlie, Kristin, Kantoff, Philip W., Berger, Michael F., Gabriel, Stacey B., Golub, Todd R., Meyerson, Matthew, Lander, Eric S., Elemento, Olivier, Getz, Gad, Demichelis, Francesca, Rubin, Mark A., Garraway, Levi A.

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An extended APOBEC3A mutation signature in cancer von Langenbucher, Adam, Bowen, Danae, Sakhtemani, Ramin, Bournique, Elodie, Wise, Jillian F., Zou, Lee, Bhagwat, Ashok S., Buisson, Rémi, Lawrence, Michael S.

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A Landscape of Driver Mutations in Melanoma von Hodis, Eran, Watson, Ian R., Kryukov, Gregory V., Arold, Stefan T., Imielinski, Marcin, Theurillat, Jean-Philippe, Nickerson, Elizabeth, Auclair, Daniel, Li, Liren, Place, Chelsea, DiCara, Daniel, Ramos, Alex H., Lawrence, Michael S., Cibulskis, Kristian, Sivachenko, Andrey, Voet, Douglas, Saksena, Gordon, Stransky, Nicolas, Onofrio, Robert C., Winckler, Wendy, Ardlie, Kristin, Wagle, Nikhil, Wargo, Jennifer, Chong, Kelly, Morton, Donald L., Stemke-Hale, Katherine, Chen, Guo, Noble, Michael, Meyerson, Matthew, Ladbury, John E., Davies, Michael A., Gershenwald, Jeffrey E., Wagner, Stephan N., Hoon, Dave S.B., Schadendorf, Dirk, Lander, Eric S., Gabriel, Stacey B., Getz, Gad, Garraway, Levi A., Chin, Lynda

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The Mutational Landscape of Head and Neck Squamous Cell Carcinoma von Stransky, Nicolas, Egloff, Ann Marie, Tward, Aaron D., Kostic, Aleksandar D., Cibulskis, Kristian, Sivachenko, Andrey, Kryukov, Gregory V., Lawrence, Michael S., Sougnez, Carrie, McKenna, Aaron, Shefler, Erica, Ramos, Alex H., Stojanov, Petar, Carter, Scott L., Voet, Douglas, Cortés, Maria L., Auclair, Daniel, Berger, Michael F., Saksena, Gordon, Guiducci, Candace, Onofrio, Robert C., Parkin, Melissa, Romkes, Marjorie, Weissfeld, Joel L., Seethala, Raja R., Wang, Lin, Rangel-Escareño, Claudia, Fernandez-Lopez, Juan Carlos, Hidalgo-Miranda, Alfredo, Melendez-Zajgla, Jorge, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Meyerson, Matthew, Lander, Eric S., Getz, Gad, Golub, Todd R., Garraway, Levi A., Grandis, Jennifer R.

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Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots von Jalili, Pégah, Bowen, Danae, Langenbucher, Adam, Park, Shinho, Aguirre, Kevin, Corcoran, Ryan B., Fleischman, Angela G., Lawrence, Michael S., Zou, Lee, Buisson, Rémi

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Comprehensive assessment of cancer missense mutation clustering in protein structures von Kamburov, Atanas, Lawrence, Michael S., Polak, Paz, Leshchiner, Ignaty, Lage, Kasper, Golub, Todd R., Lander, Eric S., Getz, Gad

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An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers von Roberts, Steven A, Lawrence, Michael S, Klimczak, Leszek J, Grimm, Sara A, Fargo, David, Stojanov, Petar, Kiezun, Adam, Kryukov, Gregory V, Carter, Scott L, Saksena, Gordon, Harris, Shawn, Shah, Ruchir R, Resnick, Michael A, Getz, Gad, Gordenin, Dmitry A

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