Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors von VRIGNAUD, Patricia, SEMIOND, Dorothée, LEJEUNE, Pascale, BOUCHARD, Hervé, CALVET, Loreley, COMBEAU, Cecile, RIOU, Jean-François, COMMERCON, Alain, LAVELLE, François, BISSERY, Marie-Christine

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Relationships between the structure of taxol analogs and their antimitotic activity von Gueritte-Voegelein, Francoise, Guenard, Daniel, Lavelle, Francois, Le Goff, Marie Therese, Mangatal, Lydie, Potier, Pierre

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In vivo treatment with CPT-11 leads to differentiation of neuroblastoma xenografts and topoisomerase I alterations von SANTOS, Alexandre, CALVET, Loreley, TERRIER-LACOMBE, Marie-Josee, LARSEN, Annette, BENARD, Jean, PONDARRE, Corinne, AUBERT, Geneviève, MORIZET, Jackie, LAVELLE, Francois, VASSAL, Gilles

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Synthesis and biological evaluation of O-alkylated tropolones and related α-ketohydroxy derivatives as ribonucleotide reductase inhibitors von Tamburlin-Thumin, Isabelle, Crozet, Michel P., Barrière, Jean-Claude, Barreau, Michel, Riou, Jean-François, Lavelle, François

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Telomerase: a therapeutic target for the third millennium? von Lavelle, François, Riou, Jean-François, Laoui, Abdelazize, Mailliet, Patrick

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Synthesis and Structure-Activity Relationships of New Antitumor Taxoids. Effects of Cyclohexyl Substitution at the C-3' and/or C-2 of Taxotere (Docetaxel) von Ojima, Iwao, Duclos, Olivier, Zucco, Martine, Bissery, Marie-Christine, Combeau, C, Vrignaud, P, Riou, J. F, Lavelle, Francois

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Preclinical Antitumor Activity and Pharmacokinetics of Irinotecan (CPT-11) in Tumor-bearing Mice von BISSERY, MARIE-CHRISTINE, VRIGNAUD, PATRICIA, LAVELLE, FRANCOIS, CHABOT, GUY G.

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The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B dis... von Mégnin-Chanet, Frédérique, Lavelle, François, Favaudon, Vincent

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RPR112378 and RPR115781: Two Representatives of a New Family of Microtubule Assembly Inhibitors von Combeau, C, Provost, J, Lancelin, F, Tournoux, Y, Prod'homme, F, Herman, F, Lavelle, F, Leboul, J, Vuilhorgne, M

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Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a taxol analogue von BISSERY, M.-C, GUENARD, D, GUERITTE-VOEGELEIN, F, LAVELLE, F

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Molecular and cellular interactions between intoplicine, DNA, and topoisomerase II studied by surface-enhanced Raman scattering spectroscopy von Morjani, H, Riou, J F, Nabiev, I, Lavelle, F, Manfait, M

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American Association for Cancer Research 1997: progress and new hope in the fight against cancer von Lavelle, Francois

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American Association for Cancer Research 1998: promises and prospects for the next century von Lavelle, Francois

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Heterocyclic quinones. XVII. A new in vivo active antineoplastic drug: 6,7-bis(1-aziridinyl)-4-[[3-(N,N-dimethylamino)propyl]amino]-5,8-quinazolinedione von Giorgi-Renault, Sylviane, Renault, Jean, Gebel-Servolles, Patricia, Baron, Michel, Paoletti, Claude, Cros, Suzanne, Bissery, Marie Christine, Lavelle, Francois, Atassi, Ghanem

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Molecular Interactions of DNA-Topoisomerase I and II Inhibitor with DNA and Topoisomerases and in Ternary Complexes: Binding Modes and Biological Effects for Intoplicine Derivative... von Nabiev, Igor, Chourpa, Igor, Riou, Jean-Francois, Nguyen, Chi Hung, Lavelle, Francois, Manfait, Michel

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Intoplicine (RP 60475) and its derivatives, a new class of antitumor agents inhibiting both topoisomerase I and II activities von RIOU, J.-F, FOSSE, P, CHI HUNG NGUYEN, LARSEN, A. K, BISSERY, M.-C, GRONDARD, L, SAUCIER, J.-M, BISAGNI, E, LAVELLE, F

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Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents von Nguyen Chi Hung, Lhoste, Jean Marc, Lavelle, Francois, Bissery, Marie Christine, Bisagni, Emile

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Dual topoisomerase I and II inhibition by intoplicine (RP-60475), a new antitumor agent in early clinical trials von PODDEVIN, B, RIOU, J.-F, LAVELLE, F, POMMIER, Y

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Domain-Structured N,N-Derivatized Hydrazines as Inhibitors of Ribonucleoside Diphosphate Reductase:  Redox-Cycling Considerations von Sarel, Shalom, Fizames, C, Lavelle, Francois, Avramovici-Grisaru, Shelly

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Purification and characterization of human DNA topoisomerase III[alpha] von Goulaouic, Helene, Roulon, Thibaut, Flamand, Odile, Grondard, Lucile, Lavelle, Francois, Riou, Jean-Francois

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