BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency von Afzali, Behdad, Grönholm, Juha, Vandrovcova, Jana, O'Brien, Charlotte, Sun, Hong-Wei, Vanderleyden, Ine, Davis, Fred P, Khoder, Ahmad, Zhang, Yu, Hegazy, Ahmed N, Villarino, Alejandro V, Palmer, Ira W, Kaufman, Joshua, Watts, Norman R, Kazemian, Majid, Kamenyeva, Olena, Keith, Julia, Sayed, Anwar, Kasperaviciute, Dalia, Mueller, Michael, Hughes, Jason D, Fuss, Ivan J, Sadiyah, Mohammed F, Montgomery-Recht, Kim, McElwee, Joshua, Restifo, Nicholas P, Strober, Warren, Linterman, Michelle A, Wingfield, Paul T, Uhlig, Holm H, Roychoudhuri, Rahul, Aitman, Timothy J, Kelleher, Peter, Lenardo, Michael J, O'Shea, John J, Cooper, Nichola, Laurence, Arian D J

Volltext

Programmed Cell Death-1 Receptor (PD-1)-Mediated Regulation of Innate Lymphoid Cells von Mallett, Grace, Laurence, Arian, Amarnath, Shoba

Volltext

The Human GP130 Cytokine Receptor and Its Expression—an Atlas and Functional Taxonomy of Genetic Variants von Chen, Yin-Huai, van Zon, Sarah, Adams, Alex, Schmidt-Arras, Dirk, Laurence, Arian D. J., Uhlig, Holm H.

Volltext

The Role of PTEN in Innate and Adaptive Immunity von Taylor, Henry, Laurence, Arian D J, Uhlig, Holm H

Volltext

Janus kinases in immune cell signaling von Ghoreschi, Kamran, Laurence, Arian, O'Shea, John J

Volltext

The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention von O'Shea, John J, Schwartz, Daniella M, Villarino, Alejandro V, Gadina, Massimo, McInnes, Iain B, Laurence, Arian

Volltext

Translational and clinical advances in JAK‐STAT biology: The present and future of jakinibs von Gadina, Massimo, Johnson, Catrina, Schwartz, Daniella, Bonelli, Michael, Hasni, Sarfaraz, Kanno, Yuka, Changelian, Paul, Laurence, Arian, O'Shea, John J.

Volltext

TH-17 differentiation: of mice and men von Laurence, Arian, O'Shea, John J

Volltext

Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells von Chauss, Daniel, Freiwald, Tilo, McGregor, Reuben, Yan, Bingyu, Wang, Luopin, Nova-Lamperti, Estefania, Kumar, Dhaneshwar, Zhang, Zonghao, Teague, Heather, West, Erin E., Vannella, Kevin M., Ramos-Benitez, Marcos J., Bibby, Jack, Kelly, Audrey, Malik, Amna, Freeman, Alexandra F., Schwartz, Daniella M., Portilla, Didier, Chertow, Daniel S., John, Susan, Lavender, Paul, Kemper, Claudia, Lombardi, Giovanna, Mehta, Nehal N., Cooper, Nichola, Lionakis, Michail S., Laurence, Arian, Kazemian, Majid, Afzali, Behdad

Volltext

Jakinibs: a new class of kinase inhibitors in cancer and autoimmune disease von Kontzias, Apostolos, Kotlyar, Alexander, Laurence, Arian, Changelian, Paul, O'Shea, John J

Volltext

Selective Regulatory Function of Socs3 in the Formation of IL-17-Secreting T Cells von Chen, Zhi, Laurence, Arian, Kanno, Yuka, Pacher-Zavisin, Margit, Zhu, Bing-Mei, Tato, Cristina, Yoshimura, Akihiko, Hennighausen, Lothar, O'Shea, John J.

Volltext

Retinoic Acid Receptor Alpha Represses a Th9 Transcriptional and Epigenomic Program to Reduce Allergic Pathology von Schwartz, Daniella M., Farley, Taylor K., Richoz, Nathan, Yao, Chen, Shih, Han-Yu, Petermann, Franziska, Zhang, Yuan, Sun, Hong-Wei, Hayes, Erika, Mikami, Yohei, Jiang, Kan, Davis, Fred P., Kanno, Yuka, Milner, Joshua D., Siegel, Richard, Laurence, Arian, Meylan, Françoise, O’Shea, John J.

Volltext

Inborn errors of IL-6 family cytokine responses von Chen, Yin-Huai, Spencer, Sarah, Laurence, Arian, Thaventhiran, James ED, Uhlig, Holm H

Volltext

Effect of Huaier granule on recurrence after curative resection of HCC: a multicentre, randomised clinical trial von Chen, Qian, Shu, Chang, Laurence, Arian D, Chen, Yan, Peng, Bao-Gang, Zhen, Zuo-Jun, Cai, Jian-Qiang, Ding, Yi-Tao, Li, Le-Qun, Zhang, Yu-Bao, Zheng, Qi-Chang, Xu, Ge-Liang, Li, Bo, Zhou, Wei-Ping, Cai, Shou-Wang, Wang, Xi-Yan, Wen, Hao, Peng, Xin-Yu, Zhang, Xue-Wen, Dai, Chao-Liu, Bie, Ping, Xing, Bao-Cai, Fu, Zhi-Ren, Liu, Lian-Xin, Mu, Yi, Zhang, Ling, Zhang, Qi-Shun, Jiang, Bin, Qian, Hai-Xin, Wang, Yi-Jun, Liu, Jing-Feng, Qin, Xi-Hu, Li, Qiang, Yin, Ping, Zhang, Zhi-Wei, Chen, Xiao-Ping

Volltext

TIF1γ and SMAD4 regulation in colorectal cancer: impact on cell proliferation and liver metastasis von Wu, Yanhui, Yu, Bin, Ai, Xi, Zhang, Wei, Chen, Weixun, Laurence, Arian, Zhang, Mingzhi, Chen, Qian, Shao, Yajie, Zhang, Bixiang

Volltext

IL-21 Is Produced by Th17 Cells and Drives IL-17 Production in a STAT3-dependent Manner von Wei, Lai, Laurence, Arian, Elias, Kevin M., O'Shea, John J.

Volltext

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells von Stathopoulou, Chaido, Gangaplara, Arunakumar, Mallett, Grace, Flomerfelt, Francis A., Liniany, Lukasz P., Knight, David, Samsel, Leigh A., Berlinguer-Palmini, Rolando, Yim, Joshua J., Felizardo, Tania C., Eckhaus, Michael A., Edgington-Mitchell, Laura, Martinez-Fabregas, Jonathan, Zhu, Jinfang, Fowler, Daniel H., van Kasteren, Sander I., Laurence, Arian, Bogyo, Matthew, Watts, Colin, Shevach, Ethan M., Amarnath, Shoba

Volltext

The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion von Xia, Yu, Liu, Na, Xie, Xiuxiu, Bi, Guoyu, Ba, Hongping, Li, Lin, Zhang, Jinxia, Deng, Xiaofei, Yao, Yao, Tang, Zhaohui, Yin, Binjiao, Wang, Jing, Jiang, Kan, Li, Zhuoya, Choi, Yongwon, Gong, Feili, Cheng, Xiang, O'Shea, John J, Chae, Jae Jin, Laurence, Arian, Yang, Xiang-Ping

Volltext

Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation von Bigley, Venetia, Maisuria, Sheetal, Cytlak, Urszula, Jardine, Laura, Care, Matthew A., Green, Kile, Gunawan, Merry, Milne, Paul, Dickinson, Rachel, Wiscombe, Sarah, Parry, David, Doffinger, Rainer, Laurence, Arian, Fonseca, Claudia, Stoevesandt, Oda, Gennery, Andrew, Cant, Andrew, Tooze, Reuben, Simpson, A. John, Hambleton, Sophie, Savic, Sinisa, Doody, Gina, Collin, Matthew

Volltext

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5 von Laurence, Arian, Yang, Xiang-Ping, Ghoreschi, Kamran, Steward-Tharp, Scott M, Rodriguez-Canales, Jaime, Zhu, Jinfang, Grainger, John R, Hirahara, Kiyoshi, Sun, Hong-Wei, Wei, Lai, Vahedi, Golnaz, Kanno, Yuka, O'Shea, John J

Volltext