Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metrics von Lau, Wan F., Withka, Jane M., Hepworth, David, Magee, Thomas V., Du, Yuhua J., Bakken, Gregory A., Miller, Michael D., Hendsch, Zachary S., Thanabal, Venkataraman, Kolodziej, Steve A., Xing, Li, Hu, Qiyue, Narasimhan, Lakshmi S., Love, Robert, Charlton, Maura E., Hughes, Samantha, van Hoorn, Willem P., Mills, James E.

Volltext

Interaction of porphyrins with human organic anion transporting polypeptide 1B1 von Campbell, Scott D., Lau, Wan F., Xu, Jinghai J.

Volltext

Thrombin active site inhibitors: chemical synthesis, in vitro and in vivo pharmacological profile of a novel and selective agent BMS-189090 and analogues von Das, Jagabandhu, Kimball, S.David, Reid, Joyce A., Wang, Tammy C., Lau, Wan F., Roberts, Daniel G.M., Seiler, Steven M., Schumacher, William A., Ogletree, Martin L.

Volltext

Retro-Binding thrombin active site inhibitors: identification of an orally active inhibitor of thrombin catalytic activity von Iwanowicz, Edwin J, Kimball, S.David, Lin, James, Lau, Wan F, Han, W.-C, Wang, Tammy C, Roberts, Daniel G.M, Schumacher, W.A, Ogletree, Martin L, Seiler, Steven M

Volltext

Retro-Binding Tripeptide Thrombin Active-Site Inhibitors: Discovery, Synthesis, and Molecular Modeling von Iwanowicz, Edwin J, Lau, Wan F, Lin, James, Roberts, Daniel G. M, Seiler, Steven M

Volltext

Selective elimination of interactions: a method for assessing thermodynamic contributions to ligand binding with application to rhinovirus antivirals von Lau, Wan F, Pettitt, B. Montgomery

Volltext

Dynamics of an oxazole compound bound to a common cold virus von Lau, Wan F, Pettitt, B. Montgomery

Volltext

The Enantioselective Synthesis of anti-β-Hydroxy-α-Amino Acids via the Reaction of Lithium Enolates of Glycine Bearing an Oxazolidine Chiral Auxiliary with Aldehydes von Iwanowicz, Edwin J., Blomgren, Peter, Cheng, Peter T. W., Smith, Kennith, Lau, Wan F., Pan, Yolanda Y., Gu, Henry H., Malley, Mary F., Gougoutas, Jack Z.

Volltext

Derivatives of 5-amidine indole as inhibitors of thrombin catalytic activity von Iwanowicz, Edwin J., Lau, Wan F., Lin, James, Roberts, Daniel G.M., Seiler, Steven M.

Volltext

Structure of a Retro-binding Peptide Inhibitor Complexed with Human α-Thrombin von Taberno, Lydia, Chang, ChiehYing Y., Ohringer, Shari L., Lau, Wan F., Iwanowicz, Edwin J., Han, Wen-Ching, Wang, Tammy C., Seiler, Steven M., Roberts, Daniel G.M., Sack, John S.

Volltext

Molecular modeling studies of novel retro-binding tripeptide active-site inhibitors of thrombin von Lau, Wan F., Tabernero, Lydia, Sack, John S., Iwanowicz, Edwin J.

Volltext

Conformations of the glycine dipeptide von Lau, Wan F., Montgomery Pettitt, B.

Volltext

1-benzazepin-2-one calcium channel blockers—VI. Receptor-binding model and possible relationship to desmethoxyverapamil von Kimball, S.David, Hunt, John T., Barrish, Joel C., Das, Jagabandhu, Floyd, David M., Lago, Michael W., Lee, Ving G., Spergel, Steven H., Moreland, Suzanne, Hedberg, S.Anders, Gougoutas, Jack Z., Malley, Mary F., Lau, Wan F.

Volltext

Molecular Dynamics of Coat Proteins of the Human Rhinovirus von Lau, Wan F., Pettitt, B. Montgomery, Lybrand, Terry P.

Volltext

A pseudopeptide incorporating the tetrahydrophthalazine nucleus, a constrained Aza analog of phenylalanine von KLINE, TONI, MUELLER, LUCIANO, SIEBER-McMASTER, ELLEN, LAU, WAN F., MEYERS, CHESTER A.

Volltext

SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS von WAN F. LAU

Volltext bestellen

Flexibility of tripeptides in solution: free energy molecular mechanics von RAMÉ, GRACIELA L., LAU, WAN F., PETTITT, B. MONTGOMERY

Volltext

Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases von MILICI ANTHONY J, CHUPAK LOUIS S, DUPLANTIER ALLEN J, LAU WAN F

Volltext bestellen

Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory, autoimmune, and respiratory diseases von Duplantier, Allen J, Chupak, Louis S, Milici, Anthony J, Lau, Wan F

Volltext bestellen

SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR XA INHIBITORS von MYERS, MICHAEL R, EWING, WILLIAM R, LI, AIWEN, POLI, GREGORY B, LAU, WAN F, BECKER, MICHAEL R, CONDON, STEPHEN M, PAULS, HEINZ W, BURNS, CHRISTOPHER J, HANNEY, BARBARA A, SPADA, ALFRED P, HE, WEI, JIANG, JOHN Z, CHOI-SLEDESKI, YONG MI, DAVIS, RODERICK S

Volltext bestellen