Electrolytic Macrocyclizations: Scalable Synthesis of a Diazonamide-Based Drug Development Candidate von Ding, Hui, DeRoy, Patrick L., Perreault, Christian, Larivée, Alexandre, Siddiqui, Arshad, Caldwell, Charles G., Harran, Susan, Harran, Patrick G.

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Shared Relations: Trauma and Kinship in the Afterlife of Death von Lloyd, Stephanie, Larivée, Alexandre

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Palladium-Catalyzed Direct C−H Arylation of N-Iminopyridinium Ylides:  Application to the Synthesis of (±)-Anabasine von Larivée, Alexandre, Mousseau, James J, Charette, André B

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Homeorhesis: envisaging the logic of life trajectories in molecular research on trauma and its effects von Lloyd, Stephanie, Larivée, Alexandre, Lutz, Pierre-Eric

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Time, trauma, and the brain: How suicide came to have no significant precipitating event von Lloyd, Stephanie, Larivée, Alexandre

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Troubling Neurobiological Vulnerability: Psychiatric Risk and the Adverse Milieu in Environmental Epigenetics Research von Filipe, Angela Marques, Lloyd, Stephanie, Larivée, Alexandre

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Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory Activity von Beveridge, Ramsay E, Wallweber, Heidi Ackerly, Ashkenazi, Avi, Beresini, Maureen, Clark, Kevin R, Gibbons, Paul, Ghiro, Elise, Kaufman, Susan, Larivée, Alexandre, Leblanc, Melissa, Leclerc, Jean-Philippe, Lemire, Alexandre, Ly, Cuong, Rudolph, Joachim, Schwarz, Jacob B, Srivastava, Sanjay, Wang, Weiru, Zhao, Liang, Braun, Marie-Gabrielle

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Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia von Varkaris, Andreas, Pazolli, Ermira, Gunaydin, Hakan, Wang, Qi, Pierce, Levi, Boezio, Alessandro A, Bulku, Artemisa, DiPietro, Lucian, Fridrich, Cary, Frost, Adam, Giordanetto, Fabrizio, Hamilton, Erika P, Harris, Katherine, Holliday, Michael, Hunter, Tamieka L, Iskandar, Amanda, Ji, Yongli, Larivée, Alexandre, LaRochelle, Jonathan R, Lescarbeau, André, Llambi, Fabien, Lormil, Brenda, Mader, Mary M, Mar, Brenton G, Martin, Iain, McLean, Thomas H, Michelsen, Klaus, Pechersky, Yakov, Puente-Poushnejad, Erika, Raynor, Kevin, Rogala, Dipali, Samadani, Ramin, Schram, Alison M, Shortsleeves, Kelley, Swaminathan, Sweta, Tajmir, Shahein, Tan, Gege, Tang, Yong, Valverde, Roberto, Wehrenberg, Bryan, Wilbur, Jeremy, Williams, Bret R, Zeng, Hongtao, Zhang, Hanmo, Walters, W Patrick, Wolf, Beni B, Shaw, David E, Bergstrom, Donald A, Watters, James, Fraser, James S, Fortin, Pascal D, Kipp, D Randal

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The Leiodolide B Puzzle von Larivée, Alexandre, Unger, John B., Thomas, Mikaël, Wirtz, Conny, Dubost, Christophe, Handa, Shinya, Fürstner, Alois

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Palladium-Catalyzed Benzylic C−H Insertion of 2-Substituted N-Iminopyridinium Ylides von Mousseau, James J, Larivée, Alexandre, Charette, André B

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Highly Regioselective Intermolecular Arylation of 1,2,3,4-Tetrahydropyridines von Pelletier, Guillaume, Larivée, Alexandre, Charette, André B

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New Methodology Toward Chiral, Non-Racemic 2,5-cis-Substituted Piperidines via Suzuki Cross-Coupling von Larivée, Alexandre, Charette, André B

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Preparation of 3-O-aryl chloramphenicol derivatives via chemoselective copper-catalyzed O-arylation of (1R,2R)-(−)-N-BOC-2-amino-1-(4-nitrophenyl)-1,3-propanediol using triarylbism... von Ahmad, Tabinda, Dansereau, Julien, Hébert, Martin, Grand-Maître, Chantal, Larivée, Alexandre, Siddiqui, Arshad, Gagnon, Alexandre

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Electrolytic Macrocyclizations: Scalable Synthesis of a Diazonamide-Based Drug Development Candidate von Ding, Hui, DeRoy, Patrick L., Perreault, Christian, Larivée, Alexandre, Siddiqui, Arshad, Caldwell, Charles G., Harran, Susan, Harran, Patrick G.

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Enantioselective Addition ofa Trifluoromethyl Anion to Aryl Ketones and Aldehydes von Caron, Stéphane, Do, Nga, Arpin, Patrice, Larivée, Alexandre

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Enantioselective Addition of a Trifluoromethyl Anion to Aryl Ketones and Aldehydes von Caron, Stéphane, Do, Nga M., Arpin, Patrice, Larivée, Alexandre

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Abstract P5-16-10: RLY-2608: The first allosteric mutant- and isoform-selective inhibitor of PI3Kα, is efficacious as a single agent and drives regressions in combination with stan... von Pazolli, Ermira, Kipp, Randy, Boezio, Alessandro, Gunaydin, Hakan, Iskandar, Amanda, Zubrowski, Matthew, Williams, Bret, Shortsleeves, Kelley, Larivee, Alexandre, McLean, Tom, Michelsen, Klaus, Zeng, Hongtao, LaRochelle, Jonathan, Manna, Joe, DiPietro, Lucian, Lescarbeau, Andre, Mader, Mary, Bennet, Bindu, Wilbur, Jeremy, Wang, Qi, Pierce, Levi, Martin, Iain, Watters, James, Fortin, Pascal, Bergstrom, Donald

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FUNCTIONALIZED TETRAHYDROFURAN INTERMEDIATE AND SYNTHESIS THEREOF von SUNCHU, Prabhakar, LEFORT, François Michel, LARIVÉE, Alexandre, ELBAUM, Daniel

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Abstract P251: Discovery and characterization of RLY-2608: The first allosteric, mutant, and isoform-selective inhibitor of PI3Kα von Pazolli, Ermira, Kipp, Randy, Boezio, Alessandro, Gunaydin, Hakan, Iskandar, Amanda, Zubrowski, Matthew, Williams, Bret, Shortsleeves, Kelley, Larivee, Alexandre, McLean, Tom, Michelsen, Klaus, Zeng, Hongtao, LaRochelle, Jonathan, Manna, Joe, DiPietro, Lucian, Mader, Mary, Bennet, Bindu, Wilbur, Jeremy, Wang, Qi, Pierce, Levi, Martin, Iain, Watters, James, Fortin, Pascal, Bergstrom, Donald

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The Leiodolide B Puzzle von Larivée, Alexandre, Unger, John B., Thomas, Mikaël, Wirtz, Conny, Dubost, Christophe, Handa, Shinya, Fürstner, Alois

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