The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy von Gunthorpe, Martin J., Large, Charles H., Sankar, Raman

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Why Is There No Cure for Tinnitus? von McFerran, Don J, Stockdale, David, Holme, Ralph, Large, Charles H, Baguley, David M

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The binding and mechanism of a positive allosteric modulator of Kv3 channels von Liang, Qiansheng, Chi, Gamma, Cirqueira, Leonardo, Zhi, Lianteng, Marasco, Agostino, Pilati, Nadia, Gunthorpe, Martin J., Alvaro, Giuseppe, Large, Charles H., Sauer, David B., Treptow, Werner, Covarrubias, Manuel

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State of the art: Pharmacologic effects on cortical excitability measures tested by transcranial magnetic stimulation von Paulus, Walter, MD, Classen, Joseph, MD, Cohen, Leonardo G., MD, Large, Charles H., PhD, Di Lazzaro, Vincenzo, MD, Nitsche, Michael, MD, Pascual-Leone, Alvaro, MD, PhD, Rosenow, F., MD, Rothwell, John C., PhD, Ziemann, Ulf, MD

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Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating von Zhang, Yalan, Zhang, Xiao-Feng, Fleming, Matthew R., Amiri, Anahita, El-Hassar, Lynda, Surguchev, Alexei A., Hyland, Callen, Jenkins, David P., Desai, Rooma, Brown, Maile R., Gazula, Valeswara-Rao, Waters, Michael F., Large, Charles H., Horvath, Tamas L., Navaratnam, Dhasakumar, Vaccarino, Flora M., Forscher, Paul, Kaczmarek, Leonard K.

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Increased spontaneous firing rates in auditory midbrain following noise exposure are specifically abolished by a Kv3 channel modulator von Anderson, Lucy A., Hesse, Lara L., Pilati, Nadia, Bakay, Warren M.H., Alvaro, Giuseppe, Large, Charles H., McAlpine, David, Schaette, Roland, Linden, Jennifer F.

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Differential Effects of Antipsychotic and Glutamatergic Agents on the phMRI Response to Phencyclidine von Gozzi, Alessandro, Large, Charles H, Schwarz, Adam, Bertani, Simone, Crestan, Valerio, Bifone, Angelo

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The spectrum of anticonvulsant efficacy of retigabine (ezogabine) in animal models: Implications for clinical use von Large, Charles H., Sokal, David M., Nehlig, Astrid, Gunthorpe, Martin J., Sankar, Raman, Crean, Christopher S., VanLandingham, Kevan E., White, H. Steve

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Mechanisms contributing to central excitability changes during hearing loss von Pilati, Nadia, Ison, Matias J, Barker, Matthew, Mulheran, Mike, Large, Charles H, Forsythe, Ian D, Matthias, John, Hamann, Martine

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Effects of lamotrigine on PCP-evoked elevations in monoamine levels in the medial prefrontal cortex of freely moving rats von Quarta, Davide, Large, Charles H

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Modulators of Kv3 Potassium Channels Rescue the Auditory Function of Fragile X Mice von El-Hassar, Lynda, Song, Lei, Tan, Winston J T, Large, Charles H, Alvaro, Giuseppe, Santos-Sacchi, Joseph, Kaczmarek, Leonard K

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Pharmacological modulation of Kv3 voltage-gated potassium channels regulates fear discrimination and expression in a response-dependent manner von Stubbendorff, Christine, Hale, Ed, Day, Harriet L.L., Smith, Jessica, Alvaro, Giuseppe S., Large, Charles H., Stevenson, Carl W.

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Kv3 K+ currents contribute to spike-timing in dorsal cochlear nucleus principal cells von Olsen, Timothy, Capurro, Alberto, Pilati, Nadia, Large, Charles H., Hamann, Martine

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Do NMDA receptor antagonist models of schizophrenia predict the clinical efficacy of antipsychotic drugs? von Large, Charles H.

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Pharmacological modulation of Kv3.1 mitigates auditory midbrain temporal processing deficits following auditory nerve damage von Chambers, Anna R., Pilati, Nadia, Balaram, Pooja, Large, Charles H., Kaczmarek, Leonard K., Polley, Daniel B.

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A balanced randomised placebo controlled blinded phase IIa multi-centre study to investigate the efficacy and safety of AUT00063 versus placebo in subjective tinnitus: The QUIET-1... von Hall, Deborah A., Ray, Jaydip, Watson, Jeannette, Sharman, Alice, Hutchison, John, Harris, Peter, Daniel, Matija, Millar, Bonnie, Large, Charles H.

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Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brain stem neurons von Brown, Maile R, El-Hassar, Lynda, Zhang, Yalan, Alvaro, Giuseppe, Large, Charles H, Kaczmarek, Leonard K

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A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons von Rosato-Siri, Marcelo D, Zambello, Erika, Mutinelli, Chiara, Garbati, Nicoletta, Benedetti, Roberto, Aldegheri, Laura, Graziani, Francesca, Virginio, Caterina, Alvaro, Giuseppe, Large, Charles H

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Effect of Kv3 channel modulators on auditory temporal resolution in aged Fischer 344 rats von Rybalko, Natalia, Popelář, Jiří, Šuta, Daniel, Svobodová Burianová, Jana, Alvaro, Giuseppe S., Large, Charles H., Syka, Josef

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Antimanic Efficacy of a Novel Kv3 Potassium Channel Modulator von Parekh, Puja K, Sidor, Michelle M, Gillman, Andrea, Becker-Krail, Darius, Bettelini, Letizia, Arban, Roberto, Alvaro, Giuseppe S, Zambello, Erika, Mutinelli, Chiara, Huang, Yanhua, Large, Charles H, McClung, Colleen A

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