Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants von Savelieva, Katerina V, Zhao, Shulei, Pogorelov, Vladimir M, Rajan, Indrani, Yang, Qi, Cullinan, Emily, Lanthorn, Thomas H

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Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain von Kostich, Walter, Hamman, Brian D, Li, Yu-Wen, Naidu, Sreenivasulu, Dandapani, Kumaran, Feng, Jianlin, Easton, Amy, Bourin, Clotilde, Baker, Kevin, Allen, Jason, Savelieva, Katerina, Louis, Justin V, Dokania, Manoj, Elavazhagan, Saravanan, Vattikundala, Pradeep, Sharma, Vivek, Das, Manish Lal, Shankar, Ganesh, Kumar, Anoop, Holenarsipur, Vinay K, Gulianello, Michael, Molski, Ted, Brown, Jeffrey M, Lewis, Martin, Huang, Yanling, Lu, Yifeng, Pieschl, Rick, O'Malley, Kevin, Lippy, Jonathan, Nouraldeen, Amr, Lanthorn, Thomas H, Ye, Guilan, Wilson, Alan, Balakrishnan, Anand, Denton, Rex, Grace, James E, Lentz, Kimberley A, Santone, Kenneth S, Bi, Yingzhi, Main, Alan, Swaffield, Jon, Carson, Ken, Mandlekar, Sandhya, Vikramadithyan, Reeba K, Nara, Susheel J, Dzierba, Carolyn, Bronson, Joanne, Macor, John E, Zaczek, Robert, Westphal, Ryan, Kiss, Laszlo, Bristow, Linda, Conway, Charles M, Zambrowicz, Brian, Albright, Charles F

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Ligation of mouse L4 and L5 spinal nerves produces robust allodynia without major motor function deficit von Ye, Gui-Lan, Savelieva, Katerina V, Vogel, Peter, Baker, Kevin B, Mason, Sara, Lanthorn, Thomas H, Rajan, Indrani

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Loss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone development von Rajan, Indrani, Savelieva, Katerina V, Ye, Gui-Lan, Wang, Ching-Yun, Malbari, Murtaza M, Friddle, Carl, Lanthorn, Thomas H, Zhang, Wandong

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Transmembrane and ubiquitin-like domain containing 1 (Tmub1) regulates locomotor activity and wakefulness in mice and interacts with CAMLG von Zhang, Wandong, Savelieva, Katerina V, Suwanichkul, Adisak, Small, Daniel L, Kirkpatrick, Laura L, Xu, Nianhua, Lanthorn, Thomas H, Ye, Gui-Lan

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Characterization of PTPRG in knockdown and phosphatase-inactive mutant mice and substrate trapping analysis of PTPRG in mammalian cells von Zhang, Wandong, Savelieva, Katerina V, Tran, David T, Pogorelov, Vladimir M, Cullinan, Emily B, Baker, Kevin B, Platt, Kenneth A, Hu, Sean, Rajan, Indrani, Xu, Nianhua, Lanthorn, Thomas H

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Diacylglycerol Lipase α Knockout Mice Demonstrate Metabolic and Behavioral Phenotypes Similar to Those of Cannabinoid Receptor 1 Knockout Mice von Powell, David R, Gay, Jason P, Wilganowski, Nathaniel, Doree, Deon, Savelieva, Katerina V, Lanthorn, Thomas H, Read, Robert, Vogel, Peter, Hansen, Gwenn M, Brommage, Robert, Ding, Zhi-Ming, Desai, Urvi, Zambrowicz, Brian

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Loss of the Putative Catalytic Domain of HDAC4 Leads to Reduced Thermal Nociception and Seizures while Allowing Normal None Development von Rajan, Indrani, Savelieva, Katerina V, Ye, Gui-Lan, Wang, Ching-yun, Malbari, Murtaza M, Friddle, Carl, Lanthorn, Thomas H, Zhang, Wandong, Chapouthier, Georges

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Novel inhibitors of the high-affinity l-proline transporter as potential therapeutic agents for the treatment of cognitive disorders von Zipp, G. Greg, Barbosa, Joseph, Green, Michael A., Terranova, Kristen M., Fink, Cynthia, Yu, Xuan-Chuan, Nouraldeen, Amr, Wilson, Alan, Savelieva, Katerina, Lanthorn, Thomas H., David Kimball, S.

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Learning and memory impairment in Eph receptor A6 knockout mice von Savelieva, Katerina V., Rajan, Indrani, Baker, Kevin B., Vogel, Peter, Jarman, Wendy, Allen, Margaret, Lanthorn, Thomas H.

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Differential sensitivity to SSRI and tricyclic antidepressants in juvenile and adult mice of three strains von Mason, Sara S., Baker, Kevin B., Davis, Kristina W., Pogorelov, Vladimir M., Malbari, Murtaza M., Ritter, Ruth, Wray, Stephen P., Gerhardt, Brenda, Lanthorn, Thomas H., Savelieva, Katerina V.

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Diacylglycerol lipase a knockout mice demonstrate metabolic and behavioral phenotypes similar to those of cannabinoid receptor 1 knockout mice von David R Powell, Jason P Gay, Nathaniel eWilganowski, Deon eDoree, Katerina V Savelieva, Thomas H Lanthorn, Robert eRead, Peter eVogel, Gwenn M Hansen, Robert eBrommage, Zhi-Ming eDing, Urvi eDesai, Brian eZambrowicz

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Discovery and characterization of potent small molecule inhibitors of the high affinity proline transporter von Yu, Xuan-Chuan, Zhang, Wandong, Oldham, Arian, Buxton, Eric, Patel, Shiv, Nghi, Nguyen, Tran, David, Lanthorn, Thomas H., Bomont, Catherine, Shi, Zhi-Cai, Liu, Qingyun

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Use of a platform in an automated open-field to enhance assessment of anxiety-like behaviors in mice von Pogorelov, Vladimir M., Lanthorn, Thomas H., Savelieva, Katerina V.

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A High-Throughput Screen for Receptor Protein Tyrosine Phosphatase–γ Selective Inhibitors von Appiah, Kingsley K., Kostich, Walter A., Gerritz, Samuel W., Huang, Yanling, Hamman, Brian D., Allen, Jason, Zhang, Wandong, Lanthorn, Thomas H., Albright, Charles F., Westphal, Ryan, Banks, Martyn N., O’Connell, Jonathan C.

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Viable mouse gene ablations that robustly alter brain Aβ levels are rare von Toyn, Jeremy H, Lin, Xu-Alan, Thompson, Mark W, Guss, Valerie, Meredith, Jr, Jere E, Sankaranarayanan, Sethu, Barrezueta, Nestor, Corradi, John, Majumdar, Antara, Small, Daniel L, Hansard, Melissa, Lanthorn, Thomas, Westphal, Ryan S, Albright, Charles F

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Diacylglycerol Lipase α Knockout Mice Demonstrate Metabolic and Behavioral Phenotypes Similar to Those of Cannabinoid Receptor 1 Knockout Mice von Powell, David R., Gay, Jason P., Wilganowski, Nathaniel, Doree, Deon, Savelieva, Katerina V., Lanthorn, Thomas H., Read, Robert, Vogel, Peter, Hansen, Gwenn M., Brommage, Robert, Ding, Zhi-Ming, Desai, Urvi, Zambrowicz, Brian

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Nicotinic agonists competitively antagonize serotonin at mouse 5-HT3 receptors expressed in Xenopus oocytes von GURLEY, D. A, LANTHORN, T. H

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Distinct ATP-activated currents in different types of neurons dissociated from rat dorsal root ganglion von Li, Chaoying, Peoples, Robert W, Lanthorn, Thomas H, Li, Zhi-Wang, Weight, Forrest F

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Ligation of mouse L4 and L5 spinal nerves produces robust allodynia without major motor function deficit: Neuropsychiatric Spectra von YE, Gui-Lan, SAVELIEVA, Katerina V, VOGEL, Peter, BAKER, Kevin B, MASON, Sara, LANTHORN, Thomas H, RAJAN, Indrani

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