Discovery and binding mode of small molecule inhibitors of the apo form of human TDO2 von Lotz-Jenne, Carina, Lange, Roland, Cren, Sylvaine, Bourquin, Geoffroy, Goglia, Laksmei, Kimmerlin, Thierry, Wicki, Micha, Müller, Manon, Artico, Nadia, Ackerknecht, Sabine, Pfaff, Philippe, Joesch, Christoph, Mac Sweeney, Aengus

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The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms von Mac Sweeney, Aengus, Chambovey, Alain, Wicki, Micha, Müller, Manon, Artico, Nadia, Lange, Roland, Bijelic, Aleksandar, Breibeck, Joscha, Rompel, Annette

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Genetic Analysis and Functional Characterization of the Streptococcus pneumoniae vic Operon von WAGNER, Christian, DE SAIZIEU, Antoine, SCHÖNFELD, Hans-Joachim, KAMBER, Markus, LANGE, Roland, THOMPSON, Charles J, PAGE, Malcolm G

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Fragment‐based screening targeting an open form of the SARS‐CoV‐2 main protease binding pocket von Huang, Chia-Ying, Metz, Alexander, Lange, Roland, Artico, Nadia, Potot, Céline, Hazemann, Julien, Müller, Manon, Dos Santos, Marina, Chambovey, Alain, Ritz, Daniel, Eris, Deniz, Meyer, Solange, Bourquin, Geoffroy, Sharpe, May, Mac Sweeney, Aengus

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Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for drug design and computational chemistry approaches von Hazemann, Julien, Kimmerlin, Thierry, Lange, Roland, Sweeney, Aengus Mac, Bourquin, Geoffroy, Ritz, Daniel, Czodrowski, Paul

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Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for de novo drug design and computational chemistry approaches von Hazemann, Julien, Kimmerlin, Thierry, Lange, Roland, Sweeney, Aengus Mac, Bourquin, Geoffroy, Ritz, Daniel, Czodrowski, Paul

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Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria von Surivet, Jean-Philippe, Panchaud, Philippe, Specklin, Jean-Luc, Diethelm, Stefan, Blumstein, Anne-Catherine, Gauvin, Jean-Christophe, Jacob, Loïc, Masse, Florence, Mathieu, Gaëlle, Mirre, Azely, Schmitt, Christine, Lange, Roland, Tidten-Luksch, Naomi, Gnerre, Carmela, Seeland, Swen, Herrmann, Charlyse, Seiler, Peter, Enderlin-Paput, Michel, Mac Sweeney, Aengus, Wicki, Micha, Hubschwerlen, Christian, Ritz, Daniel, Rueedi, Georg

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Optimization of LpxC Inhibitor Lead Compounds Focusing on Efficacy and Formulation for High Dose Intravenous Administration von Panchaud, Philippe, Surivet, Jean-Philippe, Diethelm, Stefan, Blumstein, Anne-Catherine, Gauvin, Jean-Christophe, Jacob, Loïc, Masse, Florence, Mathieu, Gaëlle, Mirre, Azely, Schmitt, Christine, Enderlin-Paput, Michel, Lange, Roland, Gnerre, Carmela, Seeland, Swen, Herrmann, Charlyse, Locher, Hans H, Seiler, Peter, Ritz, Daniel, Rueedi, Georg

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Identification and characterization of stationary phase inducible genes in Escherichia coli von Weichart, Dieter, Lange, Roland, Henneberg, Nicola, Hengge‐Aronis, Regine

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TnTIN and TnTAP: Mini-Transposons for Site-Specific Proteolysis in vivo von Ehrmann, Michael, Bolek, Petra, Mondigler, Martin, Boyd, Dana, Lange, Roland

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The Crystal Structure of E. coli 1-Deoxy- d-xylulose-5-phosphate Reductoisomerase in a Ternary Complex with the Antimalarial Compound Fosmidomycin and NADPH Reveals a Tight-binding... von Mac Sweeney, Aengus, Lange, Roland, Fernandes, Roberta P.M., Schulz, Henk, Dale, Glenn E., Douangamath, Alice, Proteau, Philip J., Oefner, Christian

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Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity von Surivet, Jean-Philippe, Lange, Roland, Hubschwerlen, Christian, Keck, Wolfgang, Specklin, Jean-Luc, Ritz, Daniel, Bur, Daniel, Locher, Hans, Seiler, Peter, Strasser, Daniel Stefan, Prade, Lars, Kohl, Christopher, Schmitt, Christine, Chapoux, Gaëlle, Ilhan, Eser, Ekambaram, Nadia, Athanasiou, Alcibiade, Knezevic, Andreja, Sabato, Daniela, Chambovey, Alain, Gaertner, Mika, Enderlin, Michel, Boehme, Maria, Sippel, Virginie, Wyss, Pierre

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Microarray-based identification of a novel Streptococcus pneumoniae regulon controlled by an autoinduced peptide von de Saizieu, A, Gardès, C, Flint, N, Wagner, C, Kamber, M, Mitchell, T J, Keck, W, Amrein, K E, Lange, R

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The nIpD gene is located in an operon with rpoS on the Escherichia coli chromosome and encodes a novel lipoprotein with a potential function in ceil wall formation von Lange, Roland, Hengge‐Aronis, Regine

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Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae von Lange, Roland, Wagner, Christian, de Saizieu, Antoine, Flint, Nicholas, Molnos, Juliette, Stieger, Martin, Caspers, Patrick, Kamber, Markus, Keck, Wolfgang, Amrein, Kurt E

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ARRANGEMENT COMPRISING A MULTI-LAYER PRINTED CIRCUIT BOARD AND METHOD FOR OPERATING A MULTI-LAYER PRINTED CIRCUIT BOARD von Morstein, Viktor, Lange, Roland

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Forward interior space arrangement for an aircraft von Heidtmann, Andreas, Lange, Roland

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A continuous coupled enzyme assay for bacterial malonyl–CoA:acyl carrier protein transacylase (FabD) von Molnos, Juliette, Gardiner, Rana, Dale, Glenn E, Lange, Roland

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Multiple Heimaten – eine Thüringen-Reise von Lange, Roland, Kolbmüller, Burkhardt, Rothe, Ulrike, Rose, Ulrike, Giller, Hanka, Gründer, Anika, Kirfel, Florian

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Arrangement in a cabin of an aircraft as well as an aircraft having such an arrangement von Heidtmann, Andreas, Lange, Roland

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