FT-4202, a selective pyruvate kinase R activator for sickle cell disease von Ericsson, Anna, Richard, David J., Wilker, Erik, Lancia, David R., Fessler, Shawn, Troccolo, Paul, Zheng, Xiaozhang, Toms, Angela, Dinsmore, Christopher, Yao, Lili, Kuypers, Frans A., Larkin, Sandra, Marcotte, Douglas, Fulzele, Keertik, Ribadeneira, Maria, Guichard, Sylvie M., Marshall, Gary

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The Impact of Variable Selection Coverage on Detection of Ligands from a DNA-Encoded Library Screen von McCarthy, Kelly A., Franklin, G. Joseph, Lancia, Jr, David R., Olbrot, Martin, Pardo, Eneida, O’Connell, Jonathan C., Kollmann, Christopher S.

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Synthesis of Multifunctional 2‑Aminobenzimidazoles on DNA via Iodine-Promoted Cyclization von Su, Liqiang, Feng, Jing, Peng, Ting, Wan, Jinqiao, Fan, Jing, Li, Jin, O’Connell, Jonathan, Lancia, David R, Franklin, G. Joseph, Liu, Guansai

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Quantitative Comparison of Enrichment from DNA-Encoded Chemical Library Selections von Faver, John C, Riehle, Kevin, Lancia, David R, Milbank, Jared B. J, Kollmann, Christopher S, Simmons, Nicholas, Yu, Zhifeng, Matzuk, Martin M

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Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11 von Martin, Matthew W., Lee, Jennifer Y., Lancia, David R., Ng, Pui Yee, Han, Bingsong, Thomason, Jennifer R., Lynes, Maureen S., Marshall, C. Gary, Conti, Chiara, Collis, Alan, Morales, Monica Alvarez, Doshi, Kshama, Rudnitskaya, Aleksandra, Yao, Lili, Zheng, Xiaozhang

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Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors von Lin, Jian, Lu, Wei, Caravella, Justin A, Campbell, Ann Marie, Diebold, R. Bruce, Ericsson, Anna, Fritzen, Edward, Gustafson, Gary R, Lancia, David R, Shelekhin, Tatiana, Wang, Zhongguo, Castro, Jennifer, Clarke, Andrea, Gotur, Deepali, Josephine, Helen R, Katz, Marie, Diep, Hien, Kershaw, Mark, Yao, Lili, Kauffman, Goss, Hubbs, Stephen E, Luke, George P, Toms, Angela V, Wang, Liann, Bair, Kenneth W, Barr, Kenneth J, Dinsmore, Christopher, Walker, Duncan, Ashwell, Susan

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Identification of Hot Spots within Druggable Binding Regions by Computational Solvent Mapping of Proteins von Landon, Melissa R, Lancia, David R, Yu, Jessamin, Thiel, Spencer C, Vajda, Sandor

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Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN) von Martin, Matthew W., Lancia, David R., Li, Hongbin, Schiller, Shawn E.R., Toms, Angela V., Wang, Zhongguo, Bair, Kenneth W., Castro, Jennifer, Fessler, Shawn, Gotur, Deepali, Hubbs, Stephen E., Kauffman, Goss S., Kershaw, Mark, Luke, George P., McKinnon, Crystal, Yao, Lili, Lu, Wei, Millan, David S.

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PRECISE: a Database of Predicted and Consensus Interaction Sites in Enzymes von Sheu, Shu-Hsien, Lancia, David R., Clodfelter, Karl H., Landon, Melissa R., Vajda, Sandor

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Clustering of domains of functionally related enzymes in the interaction database PRECISE by the generation of primary sequence patterns von Landon, Melissa R., Lancia, David R., Clodfelter, Karl H., Vajda, Sandor

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Activating pyruvate kinase R von Gustafson, Gary, Lin, Jian, Mitchell, Lorna, Richard, David, Lancia, Jr., David R, Ericsson, Anna, Green, Neal, Shelekhin, Tatiana, Zheng, Xiaozhang

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ACTIVATING PYRUVATE KINASE R von SHELEKHIN, Tatiana, LIN, Jian, LANCIA, David, R. Jr, GREEN, Neal, ERICSSON, Anna, MITCHELL, Lorna, GUSTAFSON, Gary, RICHARD, David, ZHENG, Xiaozhang

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ACTIVATING PYRUVATE KINASE R von SHELEKHIN, Tatiana, LIN, Jian, LANCIA, David, R. Jr, GREEN, Neal, ERICSSON, Anna, MITCHELL, Lorna, GUSTAFSON, Gary, RICHARD, David, ZHENG, Xiaozhang

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Bicyclic [4,6,0] hydroxamic acids as HDAC inhibitors von Lancia, Jr., David R, Ng, Pui Yee, Rudnitskaya, Aleksandra, Zheng, Xiaozhang

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Activating pyruvate kinase R von Gustafson, Gary, Marshall, Gary, Mitchell, Lorna, Richard, David, Lancia, Jr., David R, Ericsson, Anna, Green, Neal, Wang, Zhongguo

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Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators von Gustafson, Gary, Han, Bingsong, Smith, Chase C, Mitchell, Lorna, Richard, David, Lancia, Jr., David R, Ericsson, Anna, Green, Neal, Shelekhin, Tatiana, Wang, Zhongguo, Zheng, Xiaozhang

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Treating sickle cell disease with a pyruvate kinase R activating compound von Gustafson, Gary, Han, Bingsong, Smith, Chase C, Mitchell, Lorna, Richard, David, Lancia, Jr., David R, Ericsson, Anna, Green, Neal, Wang, Zhongguo, Shelekhin, Tatiana, Zheng, Xiaozhang

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Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors von Talbot, Adam Charles, Campbell, Ann-Marie, Buckmelter, Alexandre Joseph, Wang, Minghua, Lancia, Jr., David R, Follows, Bruce, Ioannidis, Stephanos

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Treating sickle cell disease with a pyruvate kinase R activating compound von Gustafson, Gary, Han, Bingsong, Smith, Chase C, Mitchell, Lorna, Richard, David, Lancia, Jr., David R, Ericsson, Anna, Green, Neal, Shelekhin, Tatiana, Wang, Zhongguo, Zheng, Xiaozhang

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Compositions for activating pyruvate kinase von Gustafson, Gary, Mitchell, Lorna, Lancia, Jr., David R, Green, Neal, Shelekhin, Tatiana, Zheng, Xiaozhang

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