Phase I dose-escalation study of F60008, a novel apoptosis inducer, in patients with advanced solid tumours von Kitzen, J.J.E.M, de Jonge, M.J.A, Lamers, C.H.J, Eskens, F.A.L.M, van der Biessen, D, van Doorn, L, ter Steeg, J, Brandely, M, Puozzo, Ch, Verweij, J

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Retroviral vectors for clinical immunogene therapy are stable for up to 9 years von Lamers, C H J, van Elzakker, P, Luider, B A, van Steenbergen, S C L, Sleijfer, S, Debets, R, Gratama, J W

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T-lymphocyte reconstitution following rigorously T-cell-depleted versus unmodified autologous stem cell transplants von TE BOEKHORST, P. A. W, LAMERS, C. H. J, SCHIPPERUS, M. R, HINTZEN, R. Q, VAN DER HOLT, B, CORNELISSEN, J. J, LÖWENBERG, B, GRATAMA, J. W

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Bone-marrow transplantation fails to halt intrathecal lymphocyte activation in multiple sclerosis von Mondria, T, Lamers, C H J, Boekhorst, P A W te, Gratama, J W, Hintzen, R Q

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Parallel detection of transduced T lymphocytes after immunogene therapy of renal cell cancer by flow cytometry and real-time polymerase chain reaction : Implications for loss of tr... von LAMERS, C. H. J, GRATAMA, J. W, POUW, N. M. C, LANGEVELD, S. C. L, VAN KRIMPEN, B. A, KRAAN, J, STOTER, G, DEBETS, R

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Process validation and clinical evaluation of a protocol to generate gene-modified T lymphocytes for imunogene therapy for metastatic renal cell carcinoma: GMP-controlled transduct... von Lamers, C.H.J., van Elzakker, P., Langeveld, S.C.L., Sleijfer, S., Gratama, J.W.

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Retronectin® -assisted retroviral transduction of primary human T lymphocytes under good manufacturing practice conditions: tissue culture bag critically determines cell yield von Lamers, C.H.J., PhD, van Elzakker, P, van Steenbergen, S.C.L, Sleijfer, S, Debets, R, Gratama, J.W

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Phoenix-ampho outperforms PG13 as retroviral packaging cells to transduce human T cells with tumor-specific receptors: implications for clinical immunogene therapy of cancer von Lamers, C H J, Willemsen, R A, van Elzakker, P, van Krimpen, B A, Gratama, J W, Debets, R

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mRNA levels of CD31, CD144, CD146 and von Willebrand factor do not serve as surrogate markers for circulating endothelial cells von Strijbos, Michiel H., van Krimpen, Brigitte A., Debets, Reno, Kraan, Jaco, Sleijfer, Stefan, Gratama, Jan Willem, Lamers, Cor H. J. J.

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Three sensitive assays do not provide evidence for circulating HuD-specific T cells in the blood of patients with paraneoplastic neurological syndromes with anti-Hu antibodies von de Jongste, Adriaan H C, de Graaf, Marieke T, Martinuzzi, Emanuela, van den Broek, Patricia D M, Kraan, Jaco, Lamers, Cor H J, Mallone, Roberto, Gratama, Jan W, Sillevis Smitt, Peter A E

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Antigen localization in the lymphoid organs of carp (Cyprinus carpio) von LAMERS, C. H. J, DE HAAS, M. J. H

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Activation of the immune system of cancer patients by continuous i.v. recombinant IL‐2 (rIL‐2) therapy is dependent on dose and schedule of rIL‐2 von GRATAMA, J. W., BRUIN, R. J., LAMERS, C. H. J., OOSTEROM, R., BRAAKMAN, E., STOTER, G., BOLHUIS, R. L. H.

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Effect of Elimination of Acid Reflux on Epithelial Cell Proliferative Activity of Barrett Esophagus von PETERS, F. T. M, GANESH, S, KUIPERS, E. J, SLUITER, W. J, KARRENBELD, A, DE JAGER-KRIKKEN, A, KLINKENBERG-KNOL, E. C, LAMERS, C. B. H. W, KLEIBEUKER, J. H

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Increased levels of soluble CD27 in the cerebrospinal fluid are not diagnostic for leptomeningeal involvement by lymphoid malignancies von VAN DEN BENT, M. J, LAMERS, C. H. J, VAN'T VEER, M. B, SMITT, P. A. E. Sillevis, BOLHUIS, R. L. H, GRATAMA, J. W

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Optimization of culture conditions for activation and large‐scale expansion of human T lymphocytes for bispecific antibody‐directed cellular immunotherapy von Lamers, C. H. J., van de Griend, R. J., Braakman, E., Ronteltap, C. P. M., Bénard, J., Stoter, G., Gratama, J. W., Bolhuis, R. L. H.

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Phase I Study of Subcutaneously Administered Recombinant Human Interleukin 12 in Patients with Advanced Renal Cell Cancer von PORTIELJE, J. E. A, KRUIT, W. H. J, AULITZKY, W. E, SCHULER, M, BECK, J, LAMERS, C. H. J, STOTER, G, HUBER, C, DE BOER-DENNERT, M, RAKHIT, A, BOLHUIS, R. L. H

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Regression of advanced ovarian carcinoma by intraperitoneal treatment with autologous T lymphocytes retargeted by a bispecific monoclonal antibody von CANEVARI, S, STOTER, G, NOOY, M. A, PARMIANI, G, RASPAGLIESI, F, RAVAGNANI, F, SCARFONE, G, TRIMBOS, J. B, WARNAAR, S. O, BOLHUIS, R. L. H, ARIENTI, F, BOLIS, G, COLNAGHI, M. I, DI RE, E. M, EGGERMONT, A. M. M, GOEY, S. H, GRATAMA, J. W, LAMERS, C. H. J

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Bone-marrow transplantation fails to halt intrathecal lymphocyte activation in multiple sclerosis von MONDRIA, T, LAMERS, C. H. J, TE BOEKHORST, P. A. W, GRATAMA, J. W, HINTZEN, R. Q

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Inhibition of bispecific monoclonal antibody (bsAb)‐targeted cytolysis by human anti‐mouse antibodies in ovarian carcinoma patients treated with bsAb‐targeted activated T‐lymphocyt... von Lamers, Cor H. J., Gratama, Jan W., Warnaar, Sven O., Stoter, Gerrit, Bolhuis, Reinder L. H.

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T-lymphocyte reconstitution following rigorously T-cell-depleted versus unmodified autologous stem cell transplants: Post-Transplant Events von te Boekhorst, P A W, Lamers, C H J, Schipperus, M R, Hintzen, R Q, van der Holt, B, Cornelissen, J J, Löwenberg, B, Gratama, J W

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