Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers von De Felice, Fernanda G, Vieira, Marcelo N.N, Bomfim, Theresa R, Decker, Helena, Velasco, Pauline T, Lambert, Mary P, Viola, Kirsten L, Zhao, Wei-Qin, Ferreira, Sergio T, Klein, William L

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Alzheimer's Disease-Affected Brain: Presence of Oligomeric Aβ Ligands (ADDLs) Suggests a Molecular Basis for Reversible Memory Loss von Gong, Yuesong, Chang, Lei, Viola, Kirsten L., Lacor, Pascale N., Lambert, Mary P., Finch, Caleb E., Krafft, Grant A., Klein, William L.

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Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo von Umeda, Tomohiro, Tomiyama, Takami, Sakama, Naomi, Tanaka, Saya, Lambert, Mary P., Klein, William L., Mori, Hiroshi

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A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo von Tomiyama, Takami, Matsuyama, Shogo, Iso, Hiroyuki, Umeda, Tomohiro, Takuma, Hiroshi, Ohnishi, Kiyouhisa, Ishibashi, Kenichi, Teraoka, Rie, Sakama, Naomi, Yamashita, Takenari, Nishitsuji, Kazuchika, Ito, Kazuhiro, Shimada, Hiroyuki, Lambert, Mary P, Klein, William L, Mori, Hiroshi

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Aβ Oligomers Induce Neuronal Oxidative Stress through an N-Methyl-D-aspartate Receptor-dependent Mechanism That Is Blocked by the Alzheimer Drug Memantine von De Felice, Fernanda G., Velasco, Pauline T., Lambert, Mary P., Viola, Kirsten, Fernandez, Sara J., Ferreira, Sergio T., Klein, William L.

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Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans von Wu, Yanjue, Wu, Zhixin, Butko, Peter, Christen, Yves, Lambert, Mary P, Klein, William L, Link, Christopher D, Luo, Yuan

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Amyloid beta oligomers induce impairment of neuronal insulin receptors von Zhao, Wei-Qin, De Felice, Fernanda G, Fernandez, Sara, Chen, Hui, Lambert, Mary P, Quon, Michael J, Krafft, Grant A, Klein, William L

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Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers von De Felice, Fernanda G, Wu, Diana, Lambert, Mary P, Fernandez, Sara J, Velasco, Pauline T, Lacor, Pascale N, Bigio, Eileen H, Jerecic, Jasna, Acton, Paul J, Shughrue, Paul J, Chen-Dodson, Elizabeth, Kinney, Gene G, Klein, William L

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Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer's disease model mice von Umeda, Tomohiro, Tomiyama, Takami, Kitajima, Erika, Idomoto, Toshiki, Nomura, Sachiko, Lambert, Mary P., Klein, William L., Mori, Hiroshi

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Temporal Profile of Amyloid- beta (A beta ) Oligomerization in an in Vivo Model of Alzheimer Disease: A LINK BETWEEN A beta AND TAU PATHOLOGY von Oddo, Salvatore, Caccamo, Antonella, Tran, Levina, Lambert, Mary P, Glabe, Charles G, Klein, William L, LaFerla, Frank M

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Synaptic targeting by Alzheimer's-related amyloid beta oligomers von Lacor, Pascale N, Buniel, Maria C, Chang, Lei, Fernandez, Sara J, Gong, Yuesong, Viola, Kirsten L, Lambert, Mary P, Velasco, Pauline T, Bigio, Eileen H, Finch, Caleb E, Krafft, Grant A, Klein, William L

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Insulin Receptor Dysfunction Impairs Cellular Clearance of Neurotoxic Oligomeric Aβ von Zhao, Wei-Qin, Lacor, Pascale N., Chen, Hui, Lambert, Mary P., Quon, Michael J., Krafft, Grant A., Klein, William L.

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The E693Δ Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid β Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Ce... von Nishitsuji, Kazuchika, Tomiyama, Takami, Ishibashi, Kenichi, Ito, Kazuhiro, Teraoka, Rie, Lambert, Mary P, Klein, William L, Mori, Hiroshi

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Monoclonal antibodies that target pathological assemblies of Aβ von Lambert, Mary P, Velasco, Pauline T, Chang, Lei, Viola, Kirsten L, Fernandez, Sara, Lacor, Pascale N, Khuon, Daliya, Gong, Yuesong, Bigio, Eileen H, Shaw, Pamela, De Felice, Fernanda G, Krafft, Grant A, Klein, William L

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CCL2 Accelerates Microglia-Mediated Aβ Oligomer Formation and Progression of Neurocognitive Dysfunction von Kiyota, Tomomi, Yamamoto, Masaru, Xiong, Huangui, Lambert, Mary P., Klein, William L., Gendelman, Howard E., Ransohoff, Richard M., Ikezu, Tsuneya

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Self-Assembly of Aβ1 - 42 into Globular Neurotoxins von Chromy, Brett A, Nowak, Richard J, Lambert, Mary P, Viola, Kirsten L, Chang, Lei, Velasco, Pauline T, Jones, Bryan W, Fernandez, Sara J, Lacor, Pascale N, Horowitz, Peleg, Finch, Caleb E, Krafft, Grant A, Klein, William L

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Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus von Wang, Hai-Wei, Pasternak, Joseph F, Kuo, Helen, Ristic, Helen, Lambert, Mary P, Chromy, Brett, Viola, Kirsten L, Klein, William L, Stine, W.Blaine, Krafft, Grant A, Trommer, Barbara L

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Vaccination with soluble Aβ oligomers generates toxicity‐neutralizing antibodies von Lambert, Mary P., Viola, Kirsten L., Chromy, Brett A., Chang, Lei, Morgan, Todd E., Yu, Jiaxin, Venton, Duane L., Krafft, Grant A., Finch, Caleb E., Klein, William L.

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AAV1/2-mediated CNS Gene Delivery of Dominant-negative CCL2 Mutant Suppresses Gliosis, β-amyloidosis, and Learning Impairment of APP/PS1 Mice von Kiyota, Tomomi, Yamamoto, Masaru, Schroder, Bryce, Jacobsen, Michael T, Swan, Russell J, Lambert, Mary P, Klein, William L, Gendelman, Howard E, Ransohoff, Richard M, Ikezu, Tsuneya

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Detection and Identification of Bioanalytes with High Resolution LSPR Spectroscopy and MALDI Mass Spectrometry von Anker, Jeffrey N, Hall, W. Paige, Lambert, Mary P, Velasco, Pauline T, Mrksich, Milan, Klein, William L, Van Duyne, Richard P

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