MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis von Samson, Andre L., Zhang, Ying, Geoghegan, Niall D., Gavin, Xavier J., Davies, Katherine A., Mlodzianoski, Michael J., Whitehead, Lachlan W., Frank, Daniel, Garnish, Sarah E., Fitzgibbon, Cheree, Hempel, Anne, Young, Samuel N., Jacobsen, Annette V., Cawthorne, Wayne, Petrie, Emma J., Faux, Maree C., Shield-Artin, Kristy, Lalaoui, Najoua, Hildebrand, Joanne M., Silke, John, Rogers, Kelly L., Lessene, Guillaume, Hawkins, Edwin D., Murphy, James M.

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Recent advances in understanding inhibitor of apoptosis proteins [version 1; peer review: 2 approved] von Lalaoui, Najoua, Vaux, David Lawrence

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Relevance of necroptosis in cancer von Lalaoui, Najoua, Brumatti, Gabriela

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MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death von Jaco, Isabel, Annibaldi, Alessandro, Lalaoui, Najoua, Wilson, Rebecca, Tenev, Tencho, Laurien, Lucie, Kim, Chun, Jamal, Kunzah, Wicky John, Sidonie, Liccardi, Gianmaria, Chau, Diep, Murphy, James M., Brumatti, Gabriela, Feltham, Rebecca, Pasparakis, Manolis, Silke, John, Meier, Pascal

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TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice von Rickard, James A, Anderton, Holly, Etemadi, Nima, Nachbur, Ueli, Darding, Maurice, Peltzer, Nieves, Lalaoui, Najoua, Lawlor, Kate E, Vanyai, Hannah, Hall, Cathrine, Bankovacki, Aleks, Gangoda, Lahiru, Wong, Wendy Wei-Lynn, Corbin, Jason, Huang, Chunzi, Mocarski, Edward S, Murphy, James M, Alexander, Warren S, Voss, Anne K, Vaux, David L, Kaiser, William J, Walczak, Henning, Silke, John

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The molecular relationships between apoptosis, autophagy and necroptosis von Lalaoui, Najoua, Lindqvist, Lisa M., Sandow, Jarrod J., Ekert, Paul G.

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The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis von Alvarez-Diaz, Silvia, Dillon, Christopher P., Lalaoui, Najoua, Tanzer, Maria C., Rodriguez, Diego A., Lin, Ann, Lebois, Marion, Hakem, Razq, Josefsson, Emma C., O’Reilly, Lorraine A., Silke, John, Alexander, Warren S., Green, Douglas R., Strasser, Andreas

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PD-L1 and IAPs co-operate to protect tumors from cytotoxic lymphocyte-derived TNF von Kearney, Conor J, Lalaoui, Najoua, Freeman, Andrew J, Ramsbottom, Kelly M, Silke, John, Oliaro, Jane

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Differential Inhibition of TRAIL-Mediated DR5-DISC Formation by Decoy Receptors 1 and 2 von Mérino, Delphine, Lalaoui, Najoua, Morizot, Alexandre, Schneider, Pascal, Solary, Eric, Micheau, Olivier

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cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner von Wong, W. Wei-Lynn, Vince, James E., Lalaoui, Najoua, Lawlor, Kate E., Chau, Diep, Bankovacki, Aleksandra, Anderton, Holly, Metcalf, Donald, O'Reilly, Lorraine, Jost, Philipp J., Murphy, James M., Alexander, Warren S., Strasser, Andreas, Vaux, David L., Silke, John

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Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation von Anderton, Holly, Rickard, James A., Varigos, George A., Lalaoui, Najoua, Silke, John

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Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3 von Petrie, Emma J., Sandow, Jarrod J., Lehmann, Wil I.L., Liang, Lung-Yu, Coursier, Diane, Young, Samuel N., Kersten, Wilhelmus J.A., Fitzgibbon, Cheree, Samson, André L., Jacobsen, Annette V., Lowes, Kym N., Au, Amanda E., Jousset Sabroux, Hélène, Lalaoui, Najoua, Webb, Andrew I., Lessene, Guillaume, Manning, Gerard, Lucet, Isabelle S., Murphy, James M.

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Targeting triple-negative breast cancers with the Smac-mimetic birinapant von Lalaoui, Najoua, Merino, Delphine, Giner, Goknur, Vaillant, François, Chau, Diep, Liu, Lin, Kratina, Tobias, Pal, Bhupinder, Whittle, James R., Etemadi, Nima, Berthelet, Jean, Gräsel, Julius, Hall, Cathrine, Ritchie, Matthew E., Ernst, Matthias, Smyth, Gordon K., Vaux, David L., Visvader, Jane E., Lindeman, Geoffrey J., Silke, John

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The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis von Moujalled, Diane, Gangatirkar, Pradnya, Kauppi, Maria, Corbin, Jason, Lebois, Marion, Murphy, James M., Lalaoui, Najoua, Hildebrand, Joanne M., Silke, John, Alexander, Warren S., Josefsson, Emma C.

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The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues von Vasanthakumar, Ajithkumar, Liao, Yang, Teh, Peggy, Pascutti, Maria F., Oja, Anna E., Garnham, Alexandra L., Gloury, Renee, Tempany, Jessica C., Sidwell, Tom, Cuadrado, Eloy, Tuijnenburg, Paul, Kuijpers, Taco W., Lalaoui, Najoua, Mielke, Lisa A., Bryant, Vanessa L., Hodgkin, Philip D., Silke, John, Smyth, Gordon K., Nolte, Martijn A., Shi, Wei, Kallies, Axel

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25 years of research put RIPK1 in the clinic von Liu, Lin, Lalaoui, Najoua

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Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis von Teh, Charis E., Lalaoui, Najoua, Jain, Reema, Policheni, Antonia N., Heinlein, Melanie, Alvarez-Diaz, Silvia, Sheridan, Julie M., Rieser, Eva, Deuser, Stefanie, Darding, Maurice, Koay, Hui-Fern, Hu, Yifang, Kupresanin, Fiona, O’Reilly, Lorraine A., Godfrey, Dale I., Smyth, Gordon K., Bouillet, Philippe, Strasser, Andreas, Walczak, Henning, Silke, John, Gray, Daniel H. D.

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TRAIL in cancer therapy: present and future challenges von Mérino, Delphine, Lalaoui, Najoua, Morizot, Alexandre, Solary, Eric, Micheau, Olivier

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Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin’s lymphoma B cells von JACQUEMIN, Guillaume, GRANCI, Virginie, GALLOUET, Anne Sophie, LALAOUI, Najoua, MORLE, Aymeric, LESSI, Elisabetta, MORIZOT, Alexandre, GARRIDO, Carmen, GUILLAUDEUX, Thierry, MICHEAU, Olivier

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TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT von Lalaoui, Najoua, Morlé, Aymeric, Mérino, Delphine, Jacquemin, Guillaume, Iessi, Elisabetta, Morizot, Alexandre, Shirley, Sarah, Robert, Bruno, Solary, Eric, Garrido, Carmen, Micheau, Olivier

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