A general protocol for the generation of Nanobodies for structural biology von Pardon, Els, Laeremans, Toon, Triest, Sarah, Rasmussen, Søren G F, Wohlkönig, Alexandre, Ruf, Armin, Muyldermans, Serge, Hol, Wim G J, Kobilka, Brian K, Steyaert, Jan

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A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action von Stoeber, Miriam, Jullié, Damien, Lobingier, Braden T., Laeremans, Toon, Steyaert, Jan, Schiller, Peter W., Manglik, Aashish, von Zastrow, Mark

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Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor von Peyrassol, Xavier, Laeremans, Toon, Gouwy, Mieke, Lahura, Vannessa, Debulpaep, Maja, Van Damme, Jo, Steyaert, Jan, Parmentier, Marc, Langer, Ingrid

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Structural basis of μ-opioid receptor targeting by a nanobody antagonist von Yu, Jun, Kumar, Amit, Zhang, Xuefeng, Martin, Charlotte, Van holsbeeck, Kevin, Raia, Pierre, Koehl, Antoine, Laeremans, Toon, Steyaert, Jan, Manglik, Aashish, Ballet, Steven, Boland, Andreas, Stoeber, Miriam

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A topological switch in CFTR modulates channel activity and sensitivity to unfolding von Scholl, Daniel, Sigoillot, Maud, Overtus, Marie, Martinez, Rafael Colomer, Martens, Chloé, Wang, Yiting, Pardon, Els, Laeremans, Toon, Garcia-Pino, Abel, Steyaert, Jan, Sheppard, David N., Hendrix, Jelle, Govaerts, Cédric

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Structure elucidation of a human melanocortin-4 receptor specific orthosteric nanobody agonist von Fontaine, Thomas, Busch, Andreas, Laeremans, Toon, De Cesco, Stéphane, Liang, Yi-Lynn, Jaakola, Veli-Pekka, Sands, Zara, Triest, Sarah, Masiulis, Simonas, Dekeyzer, Lies, Samyn, Noor, Loeys, Nicolas, Perneel, Lisa, Debaere, Melanie, Martini, Murielle, Vantieghem, Charlotte, Virmani, Richa, Skieterska, Kamila, Staelens, Stephanie, Barroco, Rosa, Van Roy, Maarten, Menet, Christel

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Domain-interface dynamics of CFTR revealed by stabilizing nanobodies von Sigoillot, Maud, Overtus, Marie, Grodecka, Magdalena, Scholl, Daniel, Garcia-Pino, Abel, Laeremans, Toon, He, Lihua, Pardon, Els, Hildebrandt, Ellen, Urbatsch, Ina, Steyaert, Jan, Riordan, John R., Govaerts, Cedric

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Structure of a bacterial type IV secretion core complex at subnanometre resolution von Rivera-Calzada, Angel, Fronzes, Rémi, Savva, Christos G, Chandran, Vidya, Lian, Pei W, Laeremans, Toon, Pardon, Els, Steyaert, Jan, Remaut, Han, Waksman, Gabriel, Orlova, Elena V

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Improved tumor targeting of anti–epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology von Tijink, Bernard M, Laeremans, Toon, Budde, Marianne, Stigter-van Walsum, Marijke, Dreier, Torsten, de Haard, Hans J, Leemans, C René, van Dongen, Guus A M S

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The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B von D'Uonnolo, Giulia, Reynders, Nathan, Meyrath, Max, Abboud, Dayana, Uchański, Tomasz, Laeremans, Toon, Volkman, Brian F, Janji, Bassam, Hanson, Julien, Szpakowska, Martyna, Chevigné, Andy

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Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs von Laeremans, Toon, Sands, Zara A, Claes, Pieter, De Blieck, Ann, De Cesco, Stephane, Triest, Sarah, Busch, Andreas, Felix, David, Kumar, Abhinav, Jaakola, Veli-Pekka, Menet, Christel

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Development by Genetic Immunization of Monovalent Antibodies Against Human Vasoactive Intestinal Peptide Receptor 1 (VPAC1), New Innovative, and Versatile Tools to Study VPAC1 Rece... von Peyrassol, Xavier, Laeremans, Toon, Lahura, Vannessa, Debulpaep, Maja, El Hassan, Hassan, Steyaert, Jan, Parmentier, Marc, Langer, Ingrid

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Modular Integrated Secretory System Engineering in Pichia pastoris To Enhance G‑Protein Coupled Receptor Expression von Claes, Katrien, Vandewalle, Kristof, Laukens, Bram, Laeremans, Toon, Vosters, Olivier, Langer, Ingrid, Parmentier, Marc, Steyaert, Jan, Callewaert, Nico

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Crystal Structure of the Intrinsically Flexible Addiction Antidote MazE von Loris, Remy, Marianovsky, Irina, Lah, Jurij, Laeremans, Toon, Engelberg-Kulka, Hanna, Glaser, Gad, Muyldermans, Serge, Wyns, Lode

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Structural insights into the activation of metabotropic glutamate receptors von Koehl, Antoine, Hu, Hongli, Feng, Dan, Sun, Bingfa, Zhang, Yan, Robertson, Michael J., Chu, Matthew, Kobilka, Tong Sun, Laeremans, Toon, Steyaert, Jan, Tarrasch, Jeffrey, Dutta, Somnath, Fonseca, Rasmus, Weis, William I., Mathiesen, Jesper M., Skiniotis, Georgios, Kobilka, Brian K.

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Propagation of conformational changes during μ-opioid receptor activation von Sounier, Rémy, Mas, Camille, Steyaert, Jan, Laeremans, Toon, Manglik, Aashish, Huang, Weijiao, Kobilka, Brian K., Déméné, Héléne, Granier, Sébastien

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Nanobody‐Enabled Reverse Pharmacology on G‐Protein‐Coupled Receptors von Pardon, Els, Betti, Cecilia, Laeremans, Toon, Chevillard, Florent, Guillemyn, Karel, Kolb, Peter, Ballet, Steven, Steyaert, Jan

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Structural insights into µ-opioid receptor activation von Huang, Weijiao, Manglik, Aashish, Venkatakrishnan, A. J., Laeremans, Toon, Feinberg, Evan N., Sanborn, Adrian L., Kato, Hideaki E., Livingston, Kathryn E., Thorsen, Thor S., Kling, Ralf C., Granier, Sébastien, Gmeiner, Peter, Husbands, Stephen M., Traynor, John R., Weis, William I., Steyaert, Jan, Dror, Ron O., Kobilka, Brian K.

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Development of Generic G Protein Peptidomimetics Able to Stabilize Active State G(s) Protein-Coupled Receptors for Application in Drug Discovery von Mannes, Morgane, Martin, Charlotte, Triest, Sarah, Pia Dimmito, Marilisa, Mollica, Adriano, Laeremans, Toon, Menet, Christel J., Ballet, Steven

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Development of Generic G Protein Peptidomimetics Able to Stabilize Active State Gs Protein‐Coupled Receptors for Application in Drug Discovery von Mannes, Morgane, Martin, Charlotte, Triest, Sarah, Pia Dimmito, Marilisa, Mollica, Adriano, Laeremans, Toon, Menet, Christel J., Ballet, Steven

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